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An overview of peptide toxins from the venom of the Chinese bird spider Selenocosmia huwena Wang [=Ornithoctonus huwena (Wang)].
Liang S. Liang S. Toxicon. 2004 Apr;43(5):575-85. doi: 10.1016/j.toxicon.2004.02.005. Toxicon. 2004. PMID: 15066414 Review.
The bird spider Selenocosmia huwena Wang [=Ornithoctonus huwena (Wang)] is one of the most venomous spiders in China. ...Eight cDNAs encoding seven toxins, HWTX-I, -II, -III, -IIIa, -IV -V, and, -VII and one lectin, S. huwena lectin-I (SHL-I), h …
The bird spider Selenocosmia huwena Wang [=Ornithoctonus huwena (Wang)] is one of the most venomous spiders in C …
Purification and characterization of a neurotoxic peptide huwentoxin-III and a natural inactive mutant from the venom of the spider Selenocosmia huwena Wang (Ornithoctonus huwena Wang).
Huang RH, Liu ZH, Liang SP. Huang RH, et al. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003 Nov;35(11):976-80. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003. PMID: 14614533 Free article.
A novel neurotoxic peptide, named huwentoxin-III, and a natural mutant have been isolated from the venom of the spider Selenocosmia huwena Wang (Ornithoctonus huwena Wang). The average molecular weights of the two peptides were determined as 3853.35 an …
A novel neurotoxic peptide, named huwentoxin-III, and a natural mutant have been isolated from the venom of the spider Selenocosmia huwen …
Proteomic and peptidomic characterization of the venom from the Chinese bird spider, Ornithoctonus huwena Wang.
Yuan C, Jin Q, Tang X, Hu W, Cao R, Yang S, Xiong J, Xie C, Xie J, Liang S. Yuan C, et al. J Proteome Res. 2007 Jul;6(7):2792-801. doi: 10.1021/pr0700192. Epub 2007 Jun 14. J Proteome Res. 2007. PMID: 17567163
The bird spider Ornithoctonus huwena Wang is a very venomous spider in China. Several compounds with different types of biological activities have been identified previously from the venom of this spider. ...The peptides display structural and pharmacological divers …
The bird spider Ornithoctonus huwena Wang is a very venomous spider in China. Several compounds with different types of biolog …
The Venom of Ornithoctonus huwena affect the electrophysiological stability of neonatal rat ventricular myocytes by inhibiting sodium, potassium and calcium current.
Yan S, Huang P, Wang Y, Zeng X, Zhang Y. Yan S, et al. Channels (Austin). 2018 Jan 1;12(1):109-118. doi: 10.1080/19336950.2018.1449497. Channels (Austin). 2018. PMID: 29532737 Free PMC article.
Spider venoms are known to contain various toxins that are used as an effective means to capture their prey or to defend themselves against predators. An investigation of the properties of Ornithoctonus huwena (O.huwena) crude venom found that the venom can block ne …
Spider venoms are known to contain various toxins that are used as an effective means to capture their prey or to defend themselves against …
Characterization of ion channels on subesophageal ganglion neurons from Chinese tarantula Ornithoctonus huwena: Exploring the myth of the spider insensitive to its venom.
Deng M, Hu Z, Cai T, Liu K, Wu W, Luo X, Jiang L, Wang M, Yang J, Xiao Y, Liang S. Deng M, et al. Toxicon. 2016 Sep 15;120:61-8. doi: 10.1016/j.toxicon.2016.07.011. Epub 2016 Jul 21. Toxicon. 2016. PMID: 27452932
Chinese tarantula Ornithoctonus huwena is one of the most venomous spiders distributing in the hilly areas of southern China. ...Huwentoxin-I and huwentoxin-IV are two abundant toxic components in the venom of Ornithoctonus huwena. Interestingly, although in our pre …
Chinese tarantula Ornithoctonus huwena is one of the most venomous spiders distributing in the hilly areas of southern China. ...Huwe …
Anti-Toxoplasma gondii effect of two spider venoms in vitro and in vivo.
Hou S, Liu Y, Tang Y, Wu M, Guan J, Li X, Wang Z, Jiang J, Deng M, Duan Z, Tang X, Han X, Jiang L. Hou S, et al. Toxicon. 2019 Aug;166:9-14. doi: 10.1016/j.toxicon.2019.05.003. Epub 2019 May 16. Toxicon. 2019. PMID: 31103717
This study was carried out to evaluate the anti-parasitic effect of spider venoms from Ornitoctonus huwena (HWVM) and Chilobrachys jingzhao (JZVM) against T. gondii tachyzoites in vitro and in vivo. ...
This study was carried out to evaluate the anti-parasitic effect of spider venoms from Ornitoctonus huwena (HWVM) and Chilobrachys ji …
Antinociceptive effects of intrathecally administered huwentoxin-I, a selective N-type calcium channel blocker, in the formalin test in conscious rats.
Chen JQ, Zhang YQ, Dai J, Luo ZM, Liang SP. Chen JQ, et al. Toxicon. 2005 Jan;45(1):15-20. doi: 10.1016/j.toxicon.2004.08.018. Toxicon. 2005. PMID: 15581678
The present study was undertaken to elucidate the antinociceptive effect of intrathecal administration of huwentoxin-I (HWTX-I), a N-type calcium channel blocker from the venom of the Chinese bird spider Ornithoctonus huwena (Wang) [=Selenocosmia huwena wa …
The present study was undertaken to elucidate the antinociceptive effect of intrathecal administration of huwentoxin-I (HWTX-I), a N-type ca …
Synthesis and characterization of huwentoxin-IV, a neurotoxin inhibiting central neuronal sodium channels.
Xiao Y, Luo X, Kuang F, Deng M, Wang M, Zeng X, Liang S. Xiao Y, et al. Toxicon. 2008 Feb;51(2):230-9. doi: 10.1016/j.toxicon.2007.09.008. Epub 2007 Sep 29. Toxicon. 2008. PMID: 18054060
Our previous work demonstrated that huwentoxin-IV was an inhibitor cystine knot peptide from Chinese tarantula Ornithoctonus huwena venom that blocked tetrodotoxin-sensitive voltage-gated sodium channels from mammalian sensory neurons [Peng, K., Shu, Q., Liu, Z., Liang, S. …
Our previous work demonstrated that huwentoxin-IV was an inhibitor cystine knot peptide from Chinese tarantula Ornithoctonus huwena v …
The cross channel activities of spider neurotoxin huwentoxin-I on rat dorsal root ganglion neurons.
Wang M, Guan X, Liang S. Wang M, et al. Biochem Biophys Res Commun. 2007 Jun 8;357(3):579-83. doi: 10.1016/j.bbrc.2007.02.168. Epub 2007 Apr 9. Biochem Biophys Res Commun. 2007. PMID: 17451655
In this paper, we investigated the action of huwentoxin-I (HWTX-I) purified from the venom of the Chinese bird spider Ornithoctonus huwena on Ca(2+), Na(+) channels of adult rat dorsal root ganglion (DRG) neurons. ...HWTX-I is the first discovered toxin with the cross chan …
In this paper, we investigated the action of huwentoxin-I (HWTX-I) purified from the venom of the Chinese bird spider Ornithoctonus huwen …
19 results