VMAT structures reveal exciting targets for drug development.
Schuldiner S, Forrest LR.
Schuldiner S, et al.
Trends Pharmacol Sci. 2024 May;45(5):385-387. doi: 10.1016/j.tips.2024.02.004. Epub 2024 Feb 29.
Trends Pharmacol Sci. 2024.
PMID: 38429134
Review.
Vesicular monoamine transporter (VMAT)-2 has a crucial role in the neurotransmission of biogenic amines. Recently, Dalton et al., Pidathala et al., Wu et al., and Wang et al. individually reported cryo-electron microscopy (EM) structures of human VMAT2, offering opportunit …
Vesicular monoamine transporter (VMAT)-2 has a crucial role in the neurotransmission of biogenic amines. Recently, Dalton et al., Pidathala …