Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2008 1
2011 1
2012 3
2015 2
2016 5
2017 1
2018 1
2019 2
2020 2
2021 2
2022 1
2023 2
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

24 results

Results by year

Filters applied: . Clear all
Page 1
Cascade Ring-Opening/Cyclization Reaction of Spiro(nitrocyclopropane)oxindoles with Huisgen Zwitterions and Synthesis of Pyrazolo[3,4-b]indoles.
Tang T, Wang Q, Cao S, Yang CJ, He Z. Tang T, et al. J Org Chem. 2022 Dec 16;87(24):16707-16721. doi: 10.1021/acs.joc.2c02375. Epub 2022 Dec 6. J Org Chem. 2022. PMID: 36473167
Herein, we report a ring-opening/cyclization cascade reaction of spiro(nitrocyclopropane)oxindoles with in situ generated Huisgen zwitterions (HZs) from PPh(3) and azodicarboxylates. This reaction provides an array of polyfunctionalized pyrazolo[3,4-b]indole derivatives in …
Herein, we report a ring-opening/cyclization cascade reaction of spiro(nitrocyclopropane)oxindoles with in situ generated Huisgen zwi …
Copper-catalyzed Huisgen and oxidative Huisgen coupling reactions controlled by polysiloxane-supported amines (AFPs) for the divergent synthesis of triazoles and bistriazoles.
Zheng ZJ, Ye F, Zheng LS, Yang KF, Lai GQ, Xu LW. Zheng ZJ, et al. Chemistry. 2012 Oct 29;18(44):14094-9. doi: 10.1002/chem.201202472. Epub 2012 Sep 27. Chemistry. 2012. PMID: 23018981
In this manuscript, we demonstrate the remarkable ability of the secondary amine-functional polysiloxane to induce oxidative coupling in the copper-mediated Huisgen reactions of azides and alkynes, thereby achieving good yields and selectivities. ...Comparably, it is also …
In this manuscript, we demonstrate the remarkable ability of the secondary amine-functional polysiloxane to induce oxidative coupling in the …
Sequential annulation and isomerisation reaction of 3-acylmethylidene oxindoles with Huisgen zwitterions and synthesis of 5-(3-oxindolyl)oxazoles.
Xue F, Yang CJ, Tang T, He Z. Xue F, et al. Org Biomol Chem. 2023 Oct 18;21(40):8176-8181. doi: 10.1039/d3ob01199b. Org Biomol Chem. 2023. PMID: 37786314
Herein, we report a facile synthesis of 5-(3-oxindolyl)oxazole derivatives via a sequential annulation and isomerisation reaction of 3-acylmethylidene oxindoles with in situ generated Huisgen zwitterions (HZs) from PPh(3) and azodicarboxylates. This reaction exhibits good …
Herein, we report a facile synthesis of 5-(3-oxindolyl)oxazole derivatives via a sequential annulation and isomerisation reaction of 3-acylm …
Annulation Reaction of 3-Acylmethylidene Oxindoles with Huisgen Zwitterions and Its Applications in the Syntheses of Pyrrolo[4,3,2-de]quinolinones and Marine Alkaloids Ammosamides.
Yang C, Chen X, Tang T, He Z. Yang C, et al. Org Lett. 2016 Mar 18;18(6):1486-9. doi: 10.1021/acs.orglett.6b00456. Epub 2016 Mar 3. Org Lett. 2016. PMID: 26938739
A novel annulation reaction of 3-acylmethylidene oxindoles with Huisgen zwitterions is unveiled that leads to an unprecedented synthetic method for complex pyrrolo[4,3,2-de]quinolinones and marine alkaloids ammosamides A-C. ...
A novel annulation reaction of 3-acylmethylidene oxindoles with Huisgen zwitterions is unveiled that leads to an unprecedented synthe …
Ether Naphthotube Host-Guest Complexes and [2]Rotaxanes with Dications.
Zheng LS, Wang SM, Jiang W, Wang LL, Yang LP. Zheng LS, et al. Chemistry. 2024 Apr 2:e202401079. doi: 10.1002/chem.202401079. Online ahead of print. Chemistry. 2024. PMID: 38563628
Based on the host-guest complexes composed of ether naphthotube and organic cations, two interlocked [2]rotaxanes were prepared by cationization reaction and Huisgen cycloaddition between the cations and the stopper components. ...
Based on the host-guest complexes composed of ether naphthotube and organic cations, two interlocked [2]rotaxanes were prepared by cationiza …
Jump-seq: Genome-Wide Capture and Amplification of 5-Hydroxymethylcytosine Sites.
Hu L, Liu Y, Han S, Yang L, Cui X, Gao Y, Dai Q, Lu X, Kou X, Zhao Y, Sheng W, Gao S, He X, He C. Hu L, et al. J Am Chem Soc. 2019 Jun 5;141(22):8694-8697. doi: 10.1021/jacs.9b02512. Epub 2019 May 23. J Am Chem Soc. 2019. PMID: 31117646 Free PMC article.
The principle of this method is to label 5hmC by the 6- N3-glucose moiety and connect a hairpin DNA oligonucleotide carrying an alkyne group to the azide-modified 5hmC via Huisgen cycloaddition (click) chemistry. Primer extension starts from the hairpin motif to the modifi …
The principle of this method is to label 5hmC by the 6- N3-glucose moiety and connect a hairpin DNA oligonucleotide carrying an alkyne group …
Hollow organic/inorganic hybrid nanoparticles from dextran-block-polypeptide copolymer: Double click reaction synthesis and properties.
Yang H, Zhang LM. Yang H, et al. Int J Biol Macromol. 2021 Jun 30;181:1243-1253. doi: 10.1016/j.ijbiomac.2021.05.101. Epub 2021 May 20. Int J Biol Macromol. 2021. PMID: 34022305
First, a polysaccharide block polypeptide diblock copolymer, dextran-block-poly(gamma-allyl-L-glutamate) (Dex-b-PALG) bearing allyl side-groups, has been synthesized by the combination of ring-opening polymerization and alkyne-azide [2 + 3] Huisgen's cycloaddition. …
First, a polysaccharide block polypeptide diblock copolymer, dextran-block-poly(gamma-allyl-L-glutamate) (Dex-b-PALG) bearing allyl side-gro …
Isatin 1,2,3-triazoles as potent inhibitors against caspase-3.
Jiang Y, Hansen TV. Jiang Y, et al. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1626-9. doi: 10.1016/j.bmcl.2011.01.110. Epub 2011 Jan 31. Bioorg Med Chem Lett. 2011. PMID: 21324681
Sixteen disubstituted 1,2,3-triazoles were prepared using the Huisgen cycloaddition reaction and evaluated as inhibitors against caspase-3. ...
Sixteen disubstituted 1,2,3-triazoles were prepared using the Huisgen cycloaddition reaction and evaluated as inhibitors against casp …
24 results