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Characterization of human beta-interferon-binding sites on human cells.
Thompson MR, Zhang Z, Fournier A, Tan YH. Thompson MR, et al. J Biol Chem. 1985 Jan 10;260(1):563-7. J Biol Chem. 1985. PMID: 2578128 Free article.
We propose the existence of at least two binding sites for HuIFN beta in Daudi cells, one site recognizing both HuIFN beta and HuIFN gamma, the other site recognizing both HuIFN beta and HuIFN alpha. Each site is capable of recognizing only H …
We propose the existence of at least two binding sites for HuIFN beta in Daudi cells, one site recognizing both HuIFN beta and …
In situ effects of interferon on human glioma protein kinase C-alpha and -beta ultrastructural localization.
Acevedo-Duncan M, Collins J, Zhang R, Haller E, Chalfant CE, Cooper DR. Acevedo-Duncan M, et al. Cell Growth Differ. 1995 Nov;6(11):1353-65. Cell Growth Differ. 1995. PMID: 8562473
In confluent cells, incubation with HuIFN alpha-2b for 2 min significantly decreased cytoplasmic PKC-beta immunoreactivity by 37%, and no change was observed in nuclear PKC-beta labeling. ...In confluent cells, cytoplasmic PKC-alpha labeling decreased 59% at 1 min, 61% at …
In confluent cells, incubation with HuIFN alpha-2b for 2 min significantly decreased cytoplasmic PKC-beta immunoreactivity by 37%, an …
Involvement of heat shock protein 27 in the susceptibility of KT human breast cancer cells to UVC and interferon lethality.
Tong XB, Kita K, Chen SP, Jiang X, Sugaya S, Jing WL, Zhang SF, Suzuki N. Tong XB, et al. Exp Ther Med. 2012 Nov;4(5):913-917. doi: 10.3892/etm.2012.696. Epub 2012 Sep 4. Exp Ther Med. 2012. PMID: 23226748 Free PMC article.
In the present study, the human breast cancer cell lines KT and MCF-7 were examined for GRP78 and HSP27 expression following exposure to UVC and human interferon-beta (HuIFN-beta). The KT cells demonstrated a higher sensitivity to both UVC and HuIFN-beta lethality t …
In the present study, the human breast cancer cell lines KT and MCF-7 were examined for GRP78 and HSP27 expression following exposure to UVC …
mRNA secondary structure at start AUG codon is a key limiting factor for human protein expression in Escherichia coli.
Zhang W, Xiao W, Wei H, Zhang J, Tian Z. Zhang W, et al. Biochem Biophys Res Commun. 2006 Oct 13;349(1):69-78. doi: 10.1016/j.bbrc.2006.07.209. Epub 2006 Aug 11. Biochem Biophys Res Commun. 2006. PMID: 16930549
However, high level expression of human protein in E. coli is still a challenge that virtually depends upon each individual target genes. Using human interleukin 10 (huIL-10) and interferon alpha (huIFN-alpha) coding sequences, we systematically analyzed the influence of s …
However, high level expression of human protein in E. coli is still a challenge that virtually depends upon each individual target genes. Us …
Effects of interferon and PKC modulators on human glioma protein kinase C, cell proliferation, and cell cycle.
Acevedo-Duncan M, Zhang R, Cooper DR, Greenberg HM. Acevedo-Duncan M, et al. Neurochem Res. 1997 Jul;22(7):775-84. doi: 10.1023/a:1022071407268. Neurochem Res. 1997. PMID: 9232628
HuIFN alpha-2b and TPA increased PKC activity, elevated the number of cells in DNA synthesis (S) phase and decreased cell proliferation by similar magnitudes. ...The response produced by HuIFN alpha-2b is similar to TPA (potent PKC activation and S phase arrest)....
HuIFN alpha-2b and TPA increased PKC activity, elevated the number of cells in DNA synthesis (S) phase and decreased cell proliferati …