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Year Number of Results
2009 1
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2012 4
2013 2
2014 8
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2023 19
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Page 1
An analytical framework for decoding cell type-specific genetic variation of gene regulation.
Xiao Y, Wang J, Li J, Zhang P, Li J, Zhou Y, Zhou Q, Chen M, Sheng X, Liu Z, Han X, Guo G. Xiao Y, et al. Nat Commun. 2023 Jun 30;14(1):3884. doi: 10.1038/s41467-023-39538-7. Nat Commun. 2023. PMID: 37391400 Free PMC article.
We apply Huatuo to generate a comprehensive cell type-specific genetic variation landscape across human tissues and further evaluate their potential roles in complex diseases and traits. Finally, we show that Huatuo's inferences permit prioritizations of driver cell …
We apply Huatuo to generate a comprehensive cell type-specific genetic variation landscape across human tissues and further evaluate …
Huatuo Zaizao pill ameliorates cognitive impairment of APP/PS1 transgenic mice by improving synaptic plasticity and reducing Abeta deposition.
Zhang JH, Yu LJ, Yang H, Hui Z, Jiang S, Chen L, Zhao Y, Wang SL, Liu Y, Xu Y. Zhang JH, et al. BMC Complement Altern Med. 2018 May 29;18(1):167. doi: 10.1186/s12906-018-2237-2. BMC Complement Altern Med. 2018. PMID: 29843688 Free PMC article.
Amyloid-beta (Abeta) deposition and synaptic dysfunction play important roles in the pathophysiology of Alzheimer's disease (AD). The Huatuo Zaizao pill (HT) is a Traditional Chinese Medicine (TCM) that has been used clinically for many years in China, mainly for post-stro …
Amyloid-beta (Abeta) deposition and synaptic dysfunction play important roles in the pathophysiology of Alzheimer's disease (AD). The Hua …
A study on inhibition of the Abeta(1-42)-induced inflammatory response by the Huatuo Zaizao pill through the NF-kappaB signaling pathway.
Jiang S, Yu LJ, Yang H, Jin Y, Chen J, Zhang JH, Liu Y, Xu Y. Jiang S, et al. Arch Med Sci. 2020 Oct 21;19(4):1136-1144. doi: 10.5114/aoms.2020.99427. eCollection 2023. Arch Med Sci. 2020. PMID: 37560736 Free PMC article.
INTRODUCTION: The pathology of Alzheimer's disease (AD) includes beta-amyloid (Abeta) (plaques) and neurofibrillary tangles (NFTs). This study aimed to explore the efficacy of Huatuo Zaizao pill (HTZP) in an AD mouse model induced by injecting Abeta(1-42), and the neuropro …
INTRODUCTION: The pathology of Alzheimer's disease (AD) includes beta-amyloid (Abeta) (plaques) and neurofibrillary tangles (NFTs). This stu …
77 results