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Hemin enhances the cardioprotective effects of mesenchymal stem cell-derived exosomes against infarction via amelioration of cardiomyocyte senescence.
Zheng H, Liang X, Han Q, Shao Z, Zhang Y, Shi L, Hong Y, Li W, Mai C, Mo Q, Fu Q, Ma X, Lin F, Li M, Hu B, Li X, Zhang Y. Zheng H, et al. J Nanobiotechnology. 2021 Oct 21;19(1):332. doi: 10.1186/s12951-021-01077-y. J Nanobiotechnology. 2021. PMID: 34674708 Free PMC article.
This study aimed to investigate the therapeutic effects of EXO derived from hemin-pretreated MSCs (Hemin-MSC-EXO) in MI and explore the potential mechanisms. METHODS: MSC-EXO and Hemin-MSC-EXO were collected and characterized. MSC-EXO and Hemin-MSC-EXO …
This study aimed to investigate the therapeutic effects of EXO derived from hemin-pretreated MSCs (Hemin-MSC-EXO) in MI and ex …
Inhibition of CCR2 attenuates neuroinflammation and neuronal apoptosis after subarachnoid hemorrhage through the PI3K/Akt pathway.
Tian Q, Guo Y, Feng S, Liu C, He P, Wang J, Han W, Yang C, Zhang Z, Li M. Tian Q, et al. J Neuroinflammation. 2022 Dec 25;19(1):312. doi: 10.1186/s12974-022-02676-8. J Neuroinflammation. 2022. PMID: 36566220 Free PMC article.
SAH grading, neurological scoring, brain water content and blood-brain barrier (BBB) permeability determination, enzyme-linked immunosorbent assay (ELISA), western blotting, and immunofluorescence were performed. An in vitro model of SAH was induced in H22 cells by hemin t …
SAH grading, neurological scoring, brain water content and blood-brain barrier (BBB) permeability determination, enzyme-linked immunosorbent …
Hemin enhances radiosensitivity of lung cancer cells through ferroptosis.
Almahi WA, Yu KN, Mohammed F, Kong P, Han W. Almahi WA, et al. Exp Cell Res. 2022 Jan 1;410(1):112946. doi: 10.1016/j.yexcr.2021.112946. Epub 2021 Nov 24. Exp Cell Res. 2022. PMID: 34826424
It was found that the presence of Hemin in irradiated lung cancer cells enhanced the productivity of initial ROS, resulting in lipid peroxidation and subsequent ferroptosis. We observed that application of Hemin as a co-treatment increased the activity of GPx4 degra …
It was found that the presence of Hemin in irradiated lung cancer cells enhanced the productivity of initial ROS, resulting in lipid …
Electrospinning of n-hemin/PAN Nanocomposite Membranes and Its Photo-Enhanced Enzyme-like Catalysis.
Han X, Tao Y, Xu C, Deng Y, Meng Z, Dou Z, Wang P, Feng Q. Han X, et al. Polymers (Basel). 2022 Nov 25;14(23):5135. doi: 10.3390/polym14235135. Polymers (Basel). 2022. PMID: 36501529 Free PMC article.
Around 42% RhB could be adsorbed in the dark, while 91% RhB decolorized under xenon lamp irradiation in 110 min, suggesting the catalytic performance of n-hemin/PAN was greatly driven by light irradiation. Differing from the axial coordinated hemin complexes, n-h
Around 42% RhB could be adsorbed in the dark, while 91% RhB decolorized under xenon lamp irradiation in 110 min, suggesting the catalytic pe …
Hemin ameliorates influenza pneumonia by attenuating lung injury and regulating the immune response.
Wang C, Zhang Y, Han L, Guo L, Zhong H, Wang J. Wang C, et al. Int J Antimicrob Agents. 2017 Jan;49(1):45-52. doi: 10.1016/j.ijantimicag.2016.09.030. Epub 2016 Nov 16. Int J Antimicrob Agents. 2017. PMID: 27884416
The human lung carcinoma cell line A549 was used to evaluate the in vitro effect of hemin on influenza A virus (IAV) replication. A mouse model was used to examine the in vivo activity of hemin. ...Pathological examination showed that hemin significantly atte …
The human lung carcinoma cell line A549 was used to evaluate the in vitro effect of hemin on influenza A virus (IAV) replication. A m …
Hemin-incorporated nanoflowers as enzyme mimics for colorimetric detection of foodborne pathogenic bacteria.
Wang KY, Bu SJ, Ju CJ, Li CT, Li ZY, Han Y, Ma CY, Wang CY, Hao Z, Liu WS, Wan JY. Wang KY, et al. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3802-3807. doi: 10.1016/j.bmcl.2018.07.017. Epub 2018 Jul 10. Bioorg Med Chem Lett. 2018. PMID: 30392778
Rapid, sensitive and point-of-care detection of foodborne pathogenic bacteria is essential for food safety. In this study, we found that hemin-concanavalin A hybrid nanoflowers (HCH nanoflowers), as solid mimic peroxidase, could catalyze oxidation of 2,2'-azino-bis (3-ethy …
Rapid, sensitive and point-of-care detection of foodborne pathogenic bacteria is essential for food safety. In this study, we found that …
A novel metal-organic framework of Co-hemin for portable and visual colorimetric detection of 2,4-dichlorophenoxyacetic acid.
Yi J, Han X, Zhu Q, Wu L, Wang Y, Xue J, Lai X, Zhou H. Yi J, et al. Anal Methods. 2022 Dec 22;15(1):63-69. doi: 10.1039/d2ay01694j. Anal Methods. 2022. PMID: 36477090
The Co-hemin biosensor exhibited a relatively low detection limit of 33 ng mL(-1) for 2,4-D by the UV method. ...Also, the Co-hemin based colorimetric biosensor showed good selectivity and specificity. ...
The Co-hemin biosensor exhibited a relatively low detection limit of 33 ng mL(-1) for 2,4-D by the UV method. ...Also, the Co-hemi
A novel metal-organic framework of Ba-hemin with enhanced cascade activity for sensitive glucose detection.
Yi J, Han X, Gao F, Cai L, Chen Y, Deng X, Li X, Xue J, Zhou H. Yi J, et al. RSC Adv. 2022 Jul 15;12(32):20544-20549. doi: 10.1039/d2ra02778j. eCollection 2022 Jul 14. RSC Adv. 2022. PMID: 35919131 Free PMC article.
Herein, we report a facile one-step biomineralization method by simply mixing aqueous solutions of hemin and barium nitrate with glucose oxidase (GOX) to form Ba-hemin@GOX composites. ...Moreover, the Ba-hemin@GOX-based colorimetric biosensor showed good sele …
Herein, we report a facile one-step biomineralization method by simply mixing aqueous solutions of hemin and barium nitrate with gluc …
Upregulation of Heme Oxygenase-1 by Hemin Alleviates Sepsis-Induced Muscle Wasting in Mice.
Yu X, Han W, Wang C, Sui D, Bian J, Bo L, Deng X. Yu X, et al. Oxid Med Cell Longev. 2018 Nov 8;2018:8927104. doi: 10.1155/2018/8927104. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 30533176 Free PMC article.
Hemin, an inducer of heme oxygenase-1 (HO-1), can enhance the activation of HO-1. ...The objective of this study was to investigate the effects of hemin on sepsis-induced skeletal muscle wasting and to explore the mechanisms by which hemin exerts its effects.
Hemin, an inducer of heme oxygenase-1 (HO-1), can enhance the activation of HO-1. ...The objective of this study was to investigate t
Hemin supports the survival of photoreceptors injured by N-Methyl-N-nitrosourea: The contributory role of neuroglobin in photoreceptor degeneration.
Tao Y, Ma Z, Liu B, Fang W, Qin L, Huang YF, Wang L, Gao Y. Tao Y, et al. Brain Res. 2018 Jan 1;1678:47-55. doi: 10.1016/j.brainres.2017.10.007. Epub 2017 Oct 13. Brain Res. 2018. PMID: 29038003
Optokinetic behavioral tests and Electroretinogram (ERG) examination suggested that the Hemin treatment could improve the visual function of MNU administered mice. ...Moreover, immunostaining experiments showed the cone photoreceptors in the MNU administered mice were also …
Optokinetic behavioral tests and Electroretinogram (ERG) examination suggested that the Hemin treatment could improve the visual func …
95 results