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Year Number of Results
1996 1
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2019 2
2020 1
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Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export.
Heybrock S, Kanerva K, Meng Y, Ing C, Liang A, Xiong ZJ, Weng X, Ah Kim Y, Collins R, Trimble W, Pomès R, Privé GG, Annaert W, Schwake M, Heeren J, Lüllmann-Rauch R, Grinstein S, Ikonen E, Saftig P, Neculai D. Heybrock S, et al. Among authors: heeren j. Nat Commun. 2019 Aug 6;10(1):3521. doi: 10.1038/s41467-019-11425-0. Nat Commun. 2019. PMID: 31387993 Free PMC article.
Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells.
Meneses-Salas E, García-Melero A, Kanerva K, Blanco-Muñoz P, Morales-Paytuvi F, Bonjoch J, Casas J, Egert A, Beevi SS, Jose J, Llorente-Cortés V, Rye KA, Heeren J, Lu A, Pol A, Tebar F, Ikonen E, Grewal T, Enrich C, Rentero C. Meneses-Salas E, et al. Among authors: heeren j. Cell Mol Life Sci. 2020 Jul;77(14):2839-2857. doi: 10.1007/s00018-019-03330-y. Epub 2019 Oct 29. Cell Mol Life Sci. 2020. PMID: 31664461 Free PMC article.
Cholesterol regulates Syntaxin 6 trafficking at trans-Golgi network endosomal boundaries.
Reverter M, Rentero C, Garcia-Melero A, Hoque M, Vilà de Muga S, Alvarez-Guaita A, Conway JR, Wood P, Cairns R, Lykopoulou L, Grinberg D, Vilageliu L, Bosch M, Heeren J, Blasi J, Timpson P, Pol A, Tebar F, Murray RZ, Grewal T, Enrich C. Reverter M, et al. Among authors: heeren j. Cell Rep. 2014 May 8;7(3):883-97. doi: 10.1016/j.celrep.2014.03.043. Epub 2014 Apr 17. Cell Rep. 2014. PMID: 24746815 Free article.
Inhibition of cholesterol export from late endosomes causes cellular cholesterol imbalance, including cholesterol depletion in the trans-Golgi network (TGN). Here, using Chinese hamster ovary (CHO) Niemann-Pick type C1 (NPC1) mutant cell lines and human NPC1 mutant fibrobl …
Inhibition of cholesterol export from late endosomes causes cellular cholesterol imbalance, including cholesterol depletion in the trans-Gol …
Inhibition of mitogen-activated protein kinase Erk1/2 promotes protein degradation of ATP binding cassette transporters A1 and G1 in CHO and HuH7 cells.
Mulay V, Wood P, Manetsch M, Darabi M, Cairns R, Hoque M, Chan KC, Reverter M, Alvarez-Guaita A, Rye KA, Rentero C, Heeren J, Enrich C, Grewal T. Mulay V, et al. Among authors: heeren j. PLoS One. 2013 Apr 25;8(4):e62667. doi: 10.1371/journal.pone.0062667. Print 2013. PLoS One. 2013. PMID: 23634230 Free PMC article.
Here we investigated if Ras/MAPK signaling could alter expression and activity of ABCA1 and ABCG1 in steroidogenic and hepatic cell lines. We demonstrate that in Chinese Hamster Ovary (CHO) cells and human hepatic HuH7 cells, extracellular signal-regulated kinase 1/2 (Erk1 …
Here we investigated if Ras/MAPK signaling could alter expression and activity of ABCA1 and ABCG1 in steroidogenic and hepatic cell lines. W …
Ras/mitogen-activated protein kinase (MAPK) signaling modulates protein stability and cell surface expression of scavenger receptor SR-BI.
Wood P, Mulay V, Darabi M, Chan KC, Heeren J, Pol A, Lambert G, Rye KA, Enrich C, Grewal T. Wood P, et al. Among authors: heeren j. J Biol Chem. 2011 Jul 1;286(26):23077-92. doi: 10.1074/jbc.M111.236398. Epub 2011 Apr 27. J Biol Chem. 2011. PMID: 21525007 Free PMC article.
Here, we investigated if the Ras-Raf-Mek-Erk1/2 signaling cascade could affect reverse cholesterol transport via modulation of scavenger receptor class BI (SR-BI) levels. We demonstrate that in Chinese hamster ovary (CHO) and human embryonic kidney (HEK293) cells, Mek1/2 i …
Here, we investigated if the Ras-Raf-Mek-Erk1/2 signaling cascade could affect reverse cholesterol transport via modulation of scavenger rec …
Cholesterol modulates the membrane binding and intracellular distribution of annexin 6.
de Diego I, Schwartz F, Siegfried H, Dauterstedt P, Heeren J, Beisiegel U, Enrich C, Grewal T. de Diego I, et al. Among authors: heeren j. J Biol Chem. 2002 Aug 30;277(35):32187-94. doi: 10.1074/jbc.M205499200. Epub 2002 Jun 17. J Biol Chem. 2002. PMID: 12070178 Free article.
We demonstrated that annexin 6 translocates to the late endocytic compartment in low density lipoprotein-loaded CHO cells. This prompted us to investigate whether cholesterol, one of the major constituents of low density lipoprotein, could influence the membrane binding af …
We demonstrated that annexin 6 translocates to the late endocytic compartment in low density lipoprotein-loaded CHO cells. This promp …
11 results