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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2005 1
2007 2
2008 1
2010 3
2011 2
2012 1
2013 1
2015 2
2016 1
2017 7
2018 4
2019 5
2020 4
2021 4
2022 9
2023 5
2024 6

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55 results

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Page 1
Berberine for gastric cancer prevention and treatment: Multi-step actions on the Correa's cascade underlie its therapeutic effects.
Liu Q, Tang J, Chen S, Hu S, Shen C, Xiang J, Chen N, Wang J, Ma X, Zhang Y, Zeng J. Liu Q, et al. Pharmacol Res. 2022 Oct;184:106440. doi: 10.1016/j.phrs.2022.106440. Epub 2022 Sep 13. Pharmacol Res. 2022. PMID: 36108874 Review.
BBR exerted multi-step actions on the Correa's cascade, thereby halting and even reversing gastric carcinogenesis in some cases. Thus, BBR could be used to prevent and treat GC. ...
BBR exerted multi-step actions on the Correa's cascade, thereby halting and even reversing gastric carcinogenesis in some cases. Thus …
Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar-Artery Occlusion.
Jovin TG, Li C, Wu L, Wu C, Chen J, Jiang C, Shi Z, Gao Z, Song C, Chen W, Peng Y, Yao C, Wei M, Li T, Wei L, Xiao G, Yang H, Ren M, Duan J, Liu X, Yang Q, Liu Y, Zhu Q, Shi W, Zhu Q, Li X, Guo Z, Yang Q, Hou C, Zhao W, Ma Q, Zhang Y, Jiao L, Zhang H, Liebeskind DS, Liang H, Jadhav AP, Wen C, Brown S, Zhu L, Ye H, Ribo M, Chang M, Song H, Chen J, Ji X; BAOCHE Investigators. Jovin TG, et al. N Engl J Med. 2022 Oct 13;387(15):1373-1384. doi: 10.1056/NEJMoa2207576. N Engl J Med. 2022. PMID: 36239645 Clinical Trial.
RESULTS: A total of 217 patients (110 in the thrombectomy group and 107 in the control group) were included in the analysis; randomization occurred at a median of 663 minutes after symptom onset. Enrollment was halted at a prespecified interim analysis because of the super …
RESULTS: A total of 217 patients (110 in the thrombectomy group and 107 in the control group) were included in the analysis; randomization o …
Shen Qi Wan attenuates renal interstitial fibrosis through upregulating AQP1.
Lin Y, Wei J, Zhang Y, Huang J, Wang S, Luo Q, Yu H, Ji L, Zhou X, Li C. Lin Y, et al. Chin J Nat Med. 2023 May;21(5):359-370. doi: 10.1016/S1875-5364(23)60453-4. Chin J Nat Med. 2023. PMID: 37245874
Renal interstitial fibrosis (RIF) is the crucial pathway in chronic kidney disease (CKD) leading to the end-stage renal failure. However, the underlying mechanism of Shen Qi Wan (SQW) on RIF is not fully understood. In the current study, we investigated the role of Aquapor …
Renal interstitial fibrosis (RIF) is the crucial pathway in chronic kidney disease (CKD) leading to the end-stage renal failure. However, th …
Photobiomodulation for Neurodegenerative Diseases: A Scoping Review.
Shen Q, Guo H, Yan Y. Shen Q, et al. Int J Mol Sci. 2024 Jan 28;25(3):1625. doi: 10.3390/ijms25031625. Int J Mol Sci. 2024. PMID: 38338901 Free PMC article. Review.
Neurodegenerative diseases involve the progressive dysfunction and loss of neurons in the central nervous system and thus present a significant challenge due to the absence of effective therapies for halting or reversing their progression. Based on the characteristics of n …
Neurodegenerative diseases involve the progressive dysfunction and loss of neurons in the central nervous system and thus present a signific …
Tubular epithelial cells-derived small extracellular vesicle-VEGF-A promotes peritubular capillary repair in ischemic kidney injury.
Zhong X, Tang TT, Shen AR, Cao JY, Jing J, Wang C, Zhu XX, Wen Y, Li ZL, Wang B, Qin SF, Liu BC, Lv LL. Zhong X, et al. NPJ Regen Med. 2022 Dec 17;7(1):73. doi: 10.1038/s41536-022-00268-x. NPJ Regen Med. 2022. PMID: 36528739 Free PMC article.
Importantly, taking advantage of the newly recognized endogenous repair response of PTCs, exogenous supplementation of VEGF-A + sEV efficiently recused PTC rarefaction, improved renal perfusion, and halted the AKI to CKD transition. Taken together, our study uncovered a no …
Importantly, taking advantage of the newly recognized endogenous repair response of PTCs, exogenous supplementation of VEGF-A + sEV efficien …
DNA Damage-Induced, S-Phase Specific Phosphorylation of Orc6 is Critical for the Maintenance of Genome Stability.
Lin YC, Liu D, Chakraborty A, Macias V, Brister E, Sonalkar J, Shen L, Mitra J, Ha T, Kajdacsy-Balla A, Prasanth KV, Prasanth SG. Lin YC, et al. Mol Cell Biol. 2023;43(4):143-156. doi: 10.1080/10985549.2023.2196204. Epub 2023 Apr 25. Mol Cell Biol. 2023. PMID: 37096556 Free PMC article.
Based on these results, we propose that DNA-damage-induced hOrc6-pThr229 phosphorylation during S-phase facilitates ATR signaling in the S-phase, halts fork progression, and enables assembly of repair factors to mediate efficient repair to prevent tumorigenesis. ...
Based on these results, we propose that DNA-damage-induced hOrc6-pThr229 phosphorylation during S-phase facilitates ATR signaling in the S-p …
Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival.
Kudryashova TV, Dabral S, Nayakanti S, Ray A, Goncharov DA, Avolio T, Shen Y, Rode A, Pena A, Jiang L, Lin D, Baust J, Bachman TN, Graumann J, Ruppert C, Guenther A, Schmoranzer M, Grobs Y, Eve Lemay S, Tremblay E, Breuils-Bonnet S, Boucherat O, Mora AL, DeLisser H, Zhao J, Zhao Y, Bonnet S, Seeger W, Pullamsetti SS, Goncharova EA. Kudryashova TV, et al. Circ Res. 2022 Mar 4;130(5):760-778. doi: 10.1161/CIRCRESAHA.121.319100. Epub 2022 Feb 7. Circ Res. 2022. PMID: 35124974 Free PMC article.
Supporting our in vitro observations, smooth muscle-specific Mst1/2 knockdown halted upregulation of Akt-mTORC1 in small muscular PAs of mice with SU5416/hypoxia-induced pulmonary hypertension. ...
Supporting our in vitro observations, smooth muscle-specific Mst1/2 knockdown halted upregulation of Akt-mTORC1 in small muscular PAs …
Towards retinal ganglion cell regeneration.
Gao H, Zhang HL, Shou J, Chen L, Shen Y, Tang Q, Huang J, Zhu J. Gao H, et al. Regen Med. 2012 Nov;7(6):865-75. doi: 10.2217/rme.12.97. Regen Med. 2012. PMID: 23164085 Review.
What is worse, neither pharmacological nor surgical interventions are significantly effective in reversing or halting the progression of vision loss. Advances in cell biology offer some hope for the victims of optic nerve damage and subsequent partial or complete visual lo …
What is worse, neither pharmacological nor surgical interventions are significantly effective in reversing or halting the progression …
(-)-Asarinin alleviates gastric precancerous lesions by promoting mitochondrial ROS accumulation and inhibiting the STAT3 signaling pathway.
Zhao M, Wen Y, Yang Y, Pan H, Xie S, Shen C, Liao W, Chen N, Zheng Q, Zhang G, Li Y, Gong D, Tang J, Zhao Z, Zeng J. Zhao M, et al. Phytomedicine. 2024 Apr;126:155348. doi: 10.1016/j.phymed.2024.155348. Epub 2024 Jan 17. Phytomedicine. 2024. PMID: 38335913
In vivo, asarinin induced ROS accumulation and inhibited the STAT3 pathway in gastric mucosa of mice, thereby halting and even reversing the development of GPL. CONCLUSION: Asarinin induces apoptosis and delays the progression of GPL by promoting mitochondrial ROS producti …
In vivo, asarinin induced ROS accumulation and inhibited the STAT3 pathway in gastric mucosa of mice, thereby halting and even revers …
REV-ERBα ameliorates heart failure through transcription repression.
Zhang L, Zhang R, Tien CL, Chan RE, Sugi K, Fu C, Griffin AC, Shen Y, Burris TP, Liao X, Jain MK. Zhang L, et al. JCI Insight. 2017 Sep 7;2(17):e95177. doi: 10.1172/jci.insight.95177. eCollection 2017 Sep 7. JCI Insight. 2017. PMID: 28878135 Free PMC article.
In vivo, REV-ERBalpha activation prevents development of cardiac hypertrophy, reduces fibrosis, and halts progression of advanced heart failure in mouse models. Thus, to our knowledge, modulation of gene networks by targeting REV-ERBalpha represents a novel approach to hea …
In vivo, REV-ERBalpha activation prevents development of cardiac hypertrophy, reduces fibrosis, and halts progression of advanced hea …
55 results