Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2007 2
2008 2
2010 1
2012 1
2013 1
2017 2
2019 1
2020 1
2022 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

12 results

Results by year

Filters applied: . Clear all
Page 1
Crystal structure of the Ate1 arginyl-tRNA-protein transferase and arginylation of N-degron substrates.
Kim BH, Kim MK, Oh SJ, Nguyen KT, Kim JH, Varshavsky A, Hwang CS, Song HK. Kim BH, et al. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2209597119. doi: 10.1073/pnas.2209597119. Epub 2022 Jul 25. Proc Natl Acad Sci U S A. 2022. PMID: 35878037 Free PMC article.
We also analyzed the inhibition of Nt-arginylation activity of Ate1 by hemin (Fe(3+)-heme), and found that hemin induced the previously undescribed disulfide-mediated oligomerization of Ate1. ...
We also analyzed the inhibition of Nt-arginylation activity of Ate1 by hemin (Fe(3+)-heme), and found that hemin induced the p …
Colorimetric biosensor using dual-amplification of enzyme-free reaction through universal hybridization chain reaction system.
Park CR, Rhee WJ, Kim KW, Hwang BH. Park CR, et al. Biotechnol Bioeng. 2019 Jul;116(7):1567-1574. doi: 10.1002/bit.26978. Epub 2019 Apr 17. Biotechnol Bioeng. 2019. PMID: 30934117
Here, we developed a novel genetic biosensor on the basis of enzyme-free dual-amplification of universal hybridization chain reaction (uHCR) and hemin/G-quadruplex horseradish peroxidase (HRP)-mimicking DNAzyme. ...
Here, we developed a novel genetic biosensor on the basis of enzyme-free dual-amplification of universal hybridization chain reaction (uHCR) …
Heme regulates exocrine peptidase precursor genes in zebrafish.
Wang H, Zhou Q, Kesinger JW, Norris C, Valdez C. Wang H, et al. Exp Biol Med (Maywood). 2007 Oct;232(9):1170-80. doi: 10.3181/0703-RM-77. Exp Biol Med (Maywood). 2007. PMID: 17895525 Free article.
We also found that ptf1a, a transcription factor regulating exocrine zymogens, is downregulated in both yquem/urod (-/-) and sau/alas2 (-/-) larvae. Further, hemin treatment rescues expression of ptf1a and these six zymogens in both yquem/urod (-/-) and sauternes/alas2 (-/ …
We also found that ptf1a, a transcription factor regulating exocrine zymogens, is downregulated in both yquem/urod (-/-) and sau/alas2 (-/-) …
Heme oxygenase-1 (HO-1)/carbon monoxide (CO) axis suppresses RANKL-induced osteoclastic differentiation by inhibiting redox-sensitive NF-κB activation.
Bak SU, Kim S, Hwang HJ, Yun JA, Kim WS, Won MH, Kim JY, Ha KS, Kwon YG, Kim YM. Bak SU, et al. BMB Rep. 2017 Feb;50(2):103-108. doi: 10.5483/bmbrep.2017.50.2.220. BMB Rep. 2017. PMID: 28088947 Free PMC article.
CORM-2 also inhibited RANKLinduced osteoclastogenesis and osteoclastic resorption activity in marrow-derived macrophages. Treatment with hemin, a HO-1 inducer, strongly inhibited RANKL-induced osteoclastogenesis in wild-type macrophages, but was ineffective in HO-1+/- cell …
CORM-2 also inhibited RANKLinduced osteoclastogenesis and osteoclastic resorption activity in marrow-derived macrophages. Treatment with …
Hemin Improves Insulin Sensitivity and Lipid Metabolism in Cultured Hepatocytes and Mice Fed a High-Fat Diet.
Luan Y, Zhang F, Cheng Y, Liu J, Huang R, Yan M, Wang Y, He Z, Lai H, Wang H, Ying H, Guo F, Zhai Q. Luan Y, et al. Nutrients. 2017 Jul 26;9(8):805. doi: 10.3390/nu9080805. Nutrients. 2017. PMID: 28933767 Free PMC article.
Hemin is a breakdown product of hemoglobin. It has been reported that the injection of hemin improves lipid metabolism and insulin sensitivity in various genetic models. However, the effect of hemin supplementation in food on lipid metabolism and insulin sens …
Hemin is a breakdown product of hemoglobin. It has been reported that the injection of hemin improves lipid metabolism and ins …
Heme oxygenase-1 attenuates epithelial-to-mesenchymal transition of human peritoneal mesothelial cells.
Bang K, Jeong J, Shin JH, Kang JH, Kim CN, Yeom HJ, Yoon MO, Yang J, Ahn C, Hwang JI, Park MY, Kim JH, Lee KW. Bang K, et al. Clin Exp Nephrol. 2013 Apr;17(2):284-93. doi: 10.1007/s10157-012-0699-y. Epub 2012 Nov 14. Clin Exp Nephrol. 2013. PMID: 23150184
We treated the human peritoneal mesothelial cells (HPMCs) with high glucose solution and HO-1 inducer (hemin, 10 mumol/L). To further investigate the pure effect of HO-1 on EMT of mesothelium, gene transfer of recombinant Adenovirus-harboring human HO-1 (Adv-HO-1 gene) to …
We treated the human peritoneal mesothelial cells (HPMCs) with high glucose solution and HO-1 inducer (hemin, 10 mumol/L). To further …
Hemin inhibits cyclin D1 and IGF-1 expression via STAT5b under hypoxia in ERalpha-negative MDA-MB 231 breast cancer cells.
Lim EJ, Joung YH, Jung SM, Park SH, Park JH, Kim SY, Hwang TS, Hong DY, Chung SC, Ye SK, Moon ES, Park EU, Park T, Chung IM, Yang YM. Lim EJ, et al. Int J Oncol. 2010 May;36(5):1243-51. doi: 10.3892/ijo_00000608. Int J Oncol. 2010. PMID: 20372799
EMSA studies showed that STAT5 binding activity to the IGF-1 and cyclin D1 promoter was distinctly decreased by hemin in STAT5b-transfected COS-7 or MDA-MB 231 cells. IGF-1 gene expression was also decreased by hemin in mammary epithelial cells. ...These data indica …
EMSA studies showed that STAT5 binding activity to the IGF-1 and cyclin D1 promoter was distinctly decreased by hemin in STAT5b-trans …
Heme oxygenase-1 mediates cytoprotection against nitric oxide-induced cytotoxicity via the cGMP pathway in human pulp cells.
Min KS, Hwang YH, Ju HJ, Chang HS, Kang KH, Pi SH, Lee SK, Lee SK, Kim EC. Min KS, et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Dec;102(6):803-8. doi: 10.1016/j.tripleo.2005.11.036. Epub 2006 May 11. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006. PMID: 17138185
RESULTS: S-nitroso-N-acetyl-D,L-penicillamine decreased cell viability, but increased HO-1 expression in a concentration- and time-dependent manner in human pulp cells. NO-induced cytotoxicity was inhibited in the presence of hemin (inducer of HO-1), whereas it was enhance …
RESULTS: S-nitroso-N-acetyl-D,L-penicillamine decreased cell viability, but increased HO-1 expression in a concentration- and time-dependent …
12 results