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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1994 1
1997 1
1999 4
2002 3
2003 2
2004 3
2005 3
2006 3
2007 5
2008 7
2009 5
2010 5
2011 13
2012 11
2013 16
2014 12
2015 26
2016 21
2017 31
2018 46
2019 52
2020 53
2021 65
2022 96
2023 101
2024 47

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564 results

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Page 1
An integrated encyclopedia of DNA elements in the human genome.
ENCODE Project Consortium. ENCODE Project Consortium. Nature. 2012 Sep 6;489(7414):57-74. doi: 10.1038/nature11247. Nature. 2012. PMID: 22955616 Free PMC article.
The newly identified elements also show a statistical correspondence to sequence variants linked to human disease, and can thereby guide interpretation of this variation. Overall, the project provides new insights into the organization and regulation of our genes and genom …
The newly identified elements also show a statistical correspondence to sequence variants linked to human disease, and can thereby guide
The role of lactate in cardiovascular diseases.
Ouyang J, Wang H, Huang J. Ouyang J, et al. Cell Commun Signal. 2023 Nov 3;21(1):317. doi: 10.1186/s12964-023-01350-7. Cell Commun Signal. 2023. PMID: 37924124 Free PMC article. Review.
The purpose of this review is to integrate relevant clinical and basic research on the role of lactate in the pathophysiological process of cardiovascular disease in recent years to clarify the important role of lactate in cardiovascular disease and to guide further studie …
The purpose of this review is to integrate relevant clinical and basic research on the role of lactate in the pathophysiological process of …
Osteoclast-targeted delivery of anti-miRNA oligonucleotides by red blood cell extracellular vesicles.
Xu L, Xu X, Liang Y, Wen C, Ouyang K, Huang J, Xiao Y, Deng X, Xia J, Duan L. Xu L, et al. J Control Release. 2023 Jun;358:259-272. doi: 10.1016/j.jconrel.2023.04.043. Epub 2023 May 5. J Control Release. 2023. PMID: 37121514
A bi-functional peptide, TBP-CP05, which binds to both the CD63 on RBCEVs and receptors on osteoclasts, acts as the guide. TBP-CP05 binds with RBCEVs through CP05, displays the TRAP-binding peptide (TBP) on the surface of EVs, and endows RBCEVs with osteoclast-targeting ca …
A bi-functional peptide, TBP-CP05, which binds to both the CD63 on RBCEVs and receptors on osteoclasts, acts as the guide. TBP-CP05 b …
ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy.
Wang M, Ran X, Leung W, Kawale A, Saxena S, Ouyang J, Patel PS, Dong Y, Yin T, Shu J, Manguso RT, Lan L, Wang XF, Lawrence MS, Zou L. Wang M, et al. Genes Dev. 2023 Oct 1;37(19-20):929-943. doi: 10.1101/gad.351084.123. Epub 2023 Nov 6. Genes Dev. 2023. PMID: 37932012 Free PMC article.
Thus, ATRi selectively targets MMR-d tumor cells by inducing synthetic lethality and enhancing antitumor immunity, providing a promising strategy to complement and augment MMR deficiency-guided immunotherapy....
Thus, ATRi selectively targets MMR-d tumor cells by inducing synthetic lethality and enhancing antitumor immunity, providing a promising str …
Blinded, randomized trial of sonographer versus AI cardiac function assessment.
He B, Kwan AC, Cho JH, Yuan N, Pollick C, Shiota T, Ebinger J, Bello NA, Wei J, Josan K, Duffy G, Jujjavarapu M, Siegel R, Cheng S, Zou JY, Ouyang D. He B, et al. Nature. 2023 Apr;616(7957):520-524. doi: 10.1038/s41586-023-05947-3. Epub 2023 Apr 5. Nature. 2023. PMID: 37020027 Free PMC article. Clinical Trial.

The mean absolute difference between final cardiologist assessment and independent previous cardiologist assessment was 6.29% in the AI group and 7.23% in the sonographer group (difference of -0.96%, 95% confidence interval: -1.34% to -0.54%, P < 0.001 for superiority). The AI

The mean absolute difference between final cardiologist assessment and independent previous cardiologist assessment was 6.29% in the AI grou …
Autophagy and pulmonary disease.
Liao SX, Sun PP, Gu YH, Rao XM, Zhang LY, Ou-Yang Y. Liao SX, et al. Ther Adv Respir Dis. 2019 Jan-Dec;13:1753466619890538. doi: 10.1177/1753466619890538. Ther Adv Respir Dis. 2019. PMID: 31771432 Free PMC article. Review.
Using recent literature on the signal transduction mechanisms of autophagy and the effects of autophagy signalling on lung diseases, this review intends to clarify the mechanisms of lung disease to guide the treatment of related diseases. The reviews of this paper are avai …
Using recent literature on the signal transduction mechanisms of autophagy and the effects of autophagy signalling on lung diseases, this re …
A framework for designing delivery systems.
Poon W, Kingston BR, Ouyang B, Ngo W, Chan WCW. Poon W, et al. Nat Nanotechnol. 2020 Oct;15(10):819-829. doi: 10.1038/s41565-020-0759-5. Epub 2020 Sep 7. Nat Nanotechnol. 2020. PMID: 32895522 Review.
We propose developing a framework for building optimal delivery systems that uses nanoparticle-biological interaction data and computational analyses to guide future nanomaterial designs and delivery strategies....
We propose developing a framework for building optimal delivery systems that uses nanoparticle-biological interaction data and computational …
Radiomics and dosiomics for predicting radiation-induced hypothyroidism and guiding intensity-modulated radiotherapy.
Yang SS, Peng QH, Wu AQ, Zhang BY, Liu ZQ, Chen EN, Xie FY, OuYang PY, Chen CY. Yang SS, et al. iScience. 2023 Nov 4;26(12):108394. doi: 10.1016/j.isci.2023.108394. eCollection 2023 Dec 15. iScience. 2023. PMID: 38047064 Free PMC article.
To guide individualized intensity-modulated radiotherapy (IMRT), we developed and prospectively validated a multiview radiomics risk model for predicting radiation-induced hypothyroidism in patients with nasopharyngeal carcinoma. ...The multiview radiomics risk model was a …
To guide individualized intensity-modulated radiotherapy (IMRT), we developed and prospectively validated a multiview radiomics risk …
Dendrimer-Based Nanogels for Cancer Nanomedicine Applications.
Mekuria SL, Ouyang Z, Song C, Rodrigues J, Shen M, Shi X. Mekuria SL, et al. Bioconjug Chem. 2022 Jan 19;33(1):87-96. doi: 10.1021/acs.bioconjchem.1c00587. Epub 2021 Dec 30. Bioconjug Chem. 2022. PMID: 34967608
In this review, we concisely surveyed the synthesis of dendrimer-based NGs synthesized via different methods including covalent conjugation, inverse nanoprecipitation, physical cross-linking, or self-assembly for various cancer nanomedicine applications, particularly for drug del …
In this review, we concisely surveyed the synthesis of dendrimer-based NGs synthesized via different methods including covalent conjugation, …
564 results