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Recent Advance in Small Molecules Targeting RhlR of Pseudomonas aeruginosa.
Lim T, Ham SY, Nam S, Kim M, Lee KY, Park HD, Byun Y. Lim T, et al. Antibiotics (Basel). 2022 Feb 19;11(2):274. doi: 10.3390/antibiotics11020274. Antibiotics (Basel). 2022. PMID: 35203876 Free PMC article. Review.
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic gram-negative pathogen that can cause various infections, particularly in patients with compromised host defenses. ...
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic gram-negative pathogen that can cause various infections, particu …
Risk factors for resistant gram-positive bacteremia in febrile neutropenic patients with cancer.
Lee M, Lee CM, Byun JM, Shin DY, Koh Y, Hong J, Choe PG, Park WB, Kim NJ, Yoon SS, Oh MD, Kang CK, Kim I. Lee M, et al. J Infect Chemother. 2024 Mar 20:S1341-321X(24)00097-7. doi: 10.1016/j.jiac.2024.03.013. Online ahead of print. J Infect Chemother. 2024. PMID: 38518846
BACKGROUND: Gram-positive bacteria are frequently resistant to empirical beta-lactams in febrile neutropenic patients with cancer. ...Episodes were compared to identify independent risk factors for resistant Gram-positive bacteremia. RESULTS: Of 225 episodes, 78 (34 …
BACKGROUND: Gram-positive bacteria are frequently resistant to empirical beta-lactams in febrile neutropenic patients with cancer. .. …
Sterile Pyometra in Two Dogs.
Yoon HY, Byun JY, Park KH, Min BS, Kim JH. Yoon HY, et al. Immune Netw. 2017 Apr;17(2):128-131. doi: 10.4110/in.2017.17.2.128. Epub 2017 Apr 20. Immune Netw. 2017. PMID: 28458625 Free PMC article.
Two young dogs were referred to the Veterinary Medical Teaching Hospital of Konkuk University, one for examination of vaginal discharge and the other after being hit by a car. Dog 1 exhibited a high neutrophil count on Gram-stained vaginal smears, marked leukocytosis on a …
Two young dogs were referred to the Veterinary Medical Teaching Hospital of Konkuk University, one for examination of vaginal discharge and …
An Intestinal Bacillus velezensis Isolate Displays Broad-Spectrum Antibacterial Activity and Prevents Infection of Both Gram-Positive and Gram-Negative Pathogens In Vivo.
Byun H, Brockett MR, Pu Q, Hrycko AJ, Beld J, Zhu J. Byun H, et al. J Bacteriol. 2023 Jun 27;205(6):e0013323. doi: 10.1128/jb.00133-23. Epub 2023 May 17. J Bacteriol. 2023. PMID: 37195186 Free PMC article.
In addition to showing that this killing effect occurred through the action of secreted antimicrobial peptides (AMPs), we demonstrate that BVM7 vegetative cells and spores can be used to treat infections of both Gram-positive and Gram-negative pathogens in vivo. By …
In addition to showing that this killing effect occurred through the action of secreted antimicrobial peptides (AMPs), we demonstrate that B …
Establishment of Experimental Murine Peritonitis Model with Hog Gastric Mucin for Carbapenem-Resistant Gram-Negative Bacteria.
Park JY, Park C, Chun HS, Byun JH, Cho SY, Lee DG. Park JY, et al. Infect Chemother. 2017 Mar;49(1):57-61. doi: 10.3947/ic.2017.49.1.57. Epub 2017 Mar 6. Infect Chemother. 2017. PMID: 28271653 Free PMC article.
This method was found to be efficient and readily applicable for investigation of carbapenem-resisant Gram-negative pathogens (e.g., Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii) detected in Korea....
This method was found to be efficient and readily applicable for investigation of carbapenem-resisant Gram-negative pathogens (e.g., …
Parabacteroides leei sp. nov., isolated from human blood.
Byun JH, Cho HW, Lee H, Lee WK, Yong D. Byun JH, et al. Int J Syst Evol Microbiol. 2023 Nov;73(11). doi: 10.1099/ijsem.0.006187. Int J Syst Evol Microbiol. 2023. PMID: 37999940
An obligate anaerobic, Gram-negative, rod-shaped and non-spore-forming bacterium, designated as strain GYB001(T), was isolated from the blood of a patient with a sigmoid colon perforation. ...
An obligate anaerobic, Gram-negative, rod-shaped and non-spore-forming bacterium, designated as strain GYB001(T), was isolated from t …
Transition-Metal-Free Alkylation and Acylation of Benzoxazinones with 1,4-Dihydropyridines.
Byun Y, Moon J, An W, Mishra NK, Kim HS, Ghosh P, Kim IS. Byun Y, et al. J Org Chem. 2021 Sep 3;86(17):12247-12256. doi: 10.1021/acs.joc.1c01558. Epub 2021 Aug 18. J Org Chem. 2021. PMID: 34406002
Excellent functional group compatibility and a broad substrate scope were attained. Gram-scale reaction and transformations of the synthesized adducts via Suzuki coupling with heteroaryl boronic acids demonstrated the synthetic potential of the developed protocol....
Excellent functional group compatibility and a broad substrate scope were attained. Gram-scale reaction and transformations of the sy …
Clinical and Laboratory Findings of Nosocomial Sepsis in Extremely Low Birth Weight Infants According to Causative Organisms.
Park KH, Park SJ, Bae MH, Jeong SH, Jeong MH, Lee N, Han YM, Byun SY. Park KH, et al. J Clin Med. 2022 Jan 4;11(1):260. doi: 10.3390/jcm11010260. J Clin Med. 2022. PMID: 35012001 Free PMC article.
We classified them into four groups according to blood culture results (gram positive, gram negative, fungal, and negative culture groups) and compared them. RESULTS: a total of 158 patients were included after using the exclusion criteria, with 45 (29%) in the g …
We classified them into four groups according to blood culture results (gram positive, gram negative, fungal, and negative cul …
Early Bactericidal Activity of Delpazolid (LCB01-0371) in Patients with Pulmonary Tuberculosis.
Kim JS, Kim YH, Lee SH, Kim YH, Kim JW, Kang JY, Kim SK, Kim SJ, Kang YS, Kim TH, Mok J, Byun MK, Park HJ, Joh JS, Park YB, Lim HS, Choi H, Lee SH, Kim H, Yang J, Kim H, Shen X, Alsultan A, Cho I, Geiter L, Shim TS. Kim JS, et al. Antimicrob Agents Chemother. 2022 Feb 15;66(2):e0168421. doi: 10.1128/AAC.01684-21. Epub 2021 Dec 6. Antimicrob Agents Chemother. 2022. PMID: 34871098 Free PMC article. Clinical Trial.
Delpazolid, an oxazolidinone, has been studied in non-clinical studies of efficacy and toxicity and Phase 1 clinical studies. Delpazolid has in vitro activity against Gram-positive bacteria, including Mycobacterium tuberculosis. This study evaluated the bactericidal activi …
Delpazolid, an oxazolidinone, has been studied in non-clinical studies of efficacy and toxicity and Phase 1 clinical studies. Delpazolid has …
Veillonella rogosae sp. nov., an anaerobic, Gram-negative coccus isolated from dental plaque.
Arif N, Do T, Byun R, Sheehy E, Clark D, Gilbert SC, Beighton D. Arif N, et al. Int J Syst Evol Microbiol. 2008 Mar;58(Pt 3):581-4. doi: 10.1099/ijs.0.65093-0. Int J Syst Evol Microbiol. 2008. PMID: 18319459 Free PMC article.
Strains of a novel anaerobic, Gram-negative coccus were isolated from the supra-gingival plaque of children. ...
Strains of a novel anaerobic, Gram-negative coccus were isolated from the supra-gingival plaque of children. ...
52 results