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Baseline clinical characteristics and disease burden in patients with paroxysmal nocturnal hemoglobinuria (PNH): updated analysis from the International PNH Registry.
Schrezenmeier H, Röth A, Araten DJ, Kanakura Y, Larratt L, Shammo JM, Wilson A, Shayan G, Maciejewski JP. Schrezenmeier H, et al. Ann Hematol. 2020 Jul;99(7):1505-1514. doi: 10.1007/s00277-020-04052-z. Epub 2020 May 10. Ann Hematol. 2020. PMID: 32390114 Free PMC article.
All patients were untreated with eculizumab at baseline, defined as date of eculizumab initiation or date of Registry enrollment (if never treated with eculizumab). Outcomes assessed in the current analysis included proportions of patients with high disease activity (HDA), …
All patients were untreated with eculizumab at baseline, defined as date of eculizumab initiation or date of Registry enrollment (if never t …
Expert opinion document: "Electrical impedance tomography: applications from the intensive care unit and beyond".
Rauseo M, Spinelli E, Sella N, Slobod D, Spadaro S, Longhini F, Giarratano A, Gilda C, Mauri T, Navalesi P; SIAARTI Study Group. Rauseo M, et al. J Anesth Analg Crit Care. 2022 Jun 21;2(1):28. doi: 10.1186/s44158-022-00055-6. J Anesth Analg Crit Care. 2022. PMID: 37386674 Free PMC article. Review.
Mechanical ventilation is a life-saving technology, but it can also inadvertently induce lung injury and increase morbidity and mortality. Currently, there is no easy method of assessing the impact that ventilator settings have on the degree of lung inssflation. ...
Mechanical ventilation is a life-saving technology, but it can also inadvertently induce lung injury and increase morbidity and mortality. …
Cardiovascular Toxicity of Immune Checkpoint Inhibitors: Clinical Risk Factors.
Pirozzi F, Poto R, Aran L, Cuomo A, Galdiero MR, Spadaro G, Abete P, Bonaduce D, Marone G, Tocchetti CG, Varricchi G, Mercurio V. Pirozzi F, et al. Curr Oncol Rep. 2021 Jan 7;23(2):13. doi: 10.1007/s11912-020-01002-w. Curr Oncol Rep. 2021. PMID: 33415405 Free PMC article. Review.
PURPOSE OF REVIEW: Immune checkpoint inhibitors, such as monoclonal antibodies targeting CTLA-4, PD-1, and PD-L1, have improved the outcome of many malignancies, but serious immune-related cardiovascular adverse events have been observed. Patients' risk factors for these toxiciti …
PURPOSE OF REVIEW: Immune checkpoint inhibitors, such as monoclonal antibodies targeting CTLA-4, PD-1, and PD-L1, have improved the outcome …
Host and Viral Proteins Modulating Ebola and Marburg Virus Egress.
Gordon TB, Hayward JA, Marsh GA, Baker ML, Tachedjian G. Gordon TB, et al. Viruses. 2019 Jan 3;11(1):25. doi: 10.3390/v11010025. Viruses. 2019. PMID: 30609802 Free PMC article. Review.
The replication cycles of these viruses are comprised of numerous complex molecular processes and interactions with their human host, with one key feature being the means by which nascent virions exit host cells to spread to new cells and ultimately to a new host. This review foc …
The replication cycles of these viruses are comprised of numerous complex molecular processes and interactions with their human host, with o …
EGFR gene status in cytological samples of nonsmall cell lung carcinoma: controversies and opportunities.
da Cunha Santos G, Saieg MA, Geddie W, Leighl N. da Cunha Santos G, et al. Cancer Cytopathol. 2011 Apr 25;119(2):80-91. doi: 10.1002/cncy.20150. Epub 2011 Mar 11. Cancer Cytopathol. 2011. PMID: 21400669 Free article. Review.
BACKGROUND: In nonsmall cell lung cancer (NSCLC), the development and clinical application of tyrosine kinase inhibitors (TKIs) targeting the epidermal growth factor receptor (EGFR) has required the investigation of EGFR status by gene copy number and/or mutation analysis. This r …
BACKGROUND: In nonsmall cell lung cancer (NSCLC), the development and clinical application of tyrosine kinase inhibitors (TKIs) targeting th …
Re-engineering Survivorship Care Plans to Support Primary Care Needs and Workflow: Results From an Engineering, Primary Care and Oncology Collaborative for Survivorship Health (EPOCH).
Tevaarwerk AJ, Zhang X, Haine J, Norslien K, Henningfield MF, Stietz C, Hahn D, Sesto ME. Tevaarwerk AJ, et al. J Cancer Educ. 2022 Dec;37(6):1654-1661. doi: 10.1007/s13187-021-02008-z. Epub 2021 Apr 26. J Cancer Educ. 2022. PMID: 33904117 Free PMC article.
Primary care clinicians have been acknowledged as important recipients of survivorship care plans (SCPs); however, current SCP templates have not been evaluated for usefulness in the primary care context. ...
Primary care clinicians have been acknowledged as important recipients of survivorship care plans (SCPs); however, current SCP templa …
Primary peritoneal carcinoma after prophylactic oophorectomy in women with a family history of ovarian cancer. A report of the Gilda Radner Familial Ovarian Cancer Registry.
Piver MS, Jishi MF, Tsukada Y, Nava G. Piver MS, et al. Cancer. 1993 May 1;71(9):2751-5. doi: 10.1002/1097-0142(19930501)71:9<2751::aid-cncr2820710911>3.0.co;2-j. Cancer. 1993. PMID: 8467455
RESULTS: From 1981 through July 1992, the Gilda Radner Familial Ovarian Cancer Registry accessioned 931 families (a total of 2221 cases of familial ovarian cancer). Currently, 324 women in these families have undergone prophylactic oophorectomy as a preventive measu …
RESULTS: From 1981 through July 1992, the Gilda Radner Familial Ovarian Cancer Registry accessioned 931 families (a total of 2221 cas …
Using the community health assessment to screen for continued driving.
Morris JN, Howard EP, Fries BE, Berkowitz R, Goldman B, David D. Morris JN, et al. Accid Anal Prev. 2014 Feb;63:104-10. doi: 10.1016/j.aap.2013.10.030. Epub 2013 Nov 2. Accid Anal Prev. 2014. PMID: 24280459 Free article.
This project used the interRAI based, community health assessment (CHA) to develop a model for identifying current elder drivers whose driving behavior should be reviewed. The assessments were completed by independent housing sites in COLLAGE, a non-profit, national senior …
This project used the interRAI based, community health assessment (CHA) to develop a model for identifying current elder drivers whos …
ERK and mTORC1 Inhibitors Enhance the Anti-Cancer Capacity of the Octpep-1 Venom-Derived Peptide in Melanoma BRAF(V600E) Mutations.
Moral-Sanz J, Fernandez-Rojo MA, Potriquet J, Mukhopadhyay P, Brust A, Wilhelm P, Smallwood TB, Clark RJ, Fry BG, Alewood PF, Waddell N, Miles JJ, Mulvenna JP, Ikonomopoulou MP. Moral-Sanz J, et al. Toxins (Basel). 2021 Feb 14;13(2):146. doi: 10.3390/toxins13020146. Toxins (Basel). 2021. PMID: 33672955 Free PMC article.
Melanoma is the main cause of skin cancer deaths, with special emphasis in those cases carrying BRAF mutations that trigger the mitogen-activated protein kinases (MAPK) signaling and unrestrained cell proliferation in the absence of mitogens. Current therapies targeting MA …
Melanoma is the main cause of skin cancer deaths, with special emphasis in those cases carrying BRAF mutations that trigger the mitogen-acti …
Can Joan of Arc Serve as an Enduring Model of Empowerment for Women With a Cancer Diagnosis?
Roseman JL. Roseman JL. Adv Mind Body Med. 2016 Winter;30(1):23-7. Adv Mind Body Med. 2016. PMID: 26878679
PARTICIPANTS: Participants were 10 female survivors of cancer who were members of the Gilda's Club. INTERVENTION: Participants took part in a 6-wk workshop. The workshop included arts-based medicine and meditations, based on a book written by the current author. OUT …
PARTICIPANTS: Participants were 10 female survivors of cancer who were members of the Gilda's Club. INTERVENTION: Participants took p …
19 results