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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1912 2
1913 1
1914 1
1919 7
1920 5
1921 5
1922 1
1923 4
1924 1
1926 1
1927 2
1928 2
1929 1
1930 1
1931 3
1932 7
1933 6
1934 2
1935 4
1936 4
1937 3
1938 1
1939 3
1940 1
1941 1
1942 4
1943 3
1944 5
1945 11
1946 29
1947 33
1948 38
1949 16
1950 21
1951 24
1952 18
1953 25
1954 22
1955 24
1956 35
1957 26
1958 44
1959 33
1960 43
1961 52
1962 52
1963 81
1964 225
1965 264
1966 400
1967 594
1968 937
1969 1164
1970 1340
1971 1675
1972 1855
1973 2096
1974 2596
1975 2806
1976 3059
1977 3236
1978 3604
1979 3927
1980 4249
1981 4607
1982 5402
1983 6430
1984 7380
1985 8410
1986 9714
1987 11831
1988 13346
1989 15705
1990 17484
1991 19111
1992 20782
1993 23661
1994 25817
1995 27598
1996 28385
1997 30044
1998 31852
1999 33413
2000 37178
2001 38836
2002 40381
2003 42974
2004 47183
2005 50099
2006 53342
2007 55638
2008 57721
2009 58988
2010 62943
2011 66944
2012 71283
2013 73454
2014 76060
2015 78072
2016 79060
2017 77966
2018 80500
2019 86392
2020 94224
2021 102605
2022 102226
2023 95908
2024 36799

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Search Results

1,870,023 results

Results by year

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Page 1
Genome-wide analysis of somatic noncoding mutation patterns in cancer.
Dietlein F, Wang AB, Fagre C, Tang A, Besselink NJM, Cuppen E, Li C, Sunyaev SR, Neal JT, Van Allen EM. Dietlein F, et al. Science. 2022 Apr 8;376(6589):eabg5601. doi: 10.1126/science.abg5601. Epub 2022 Apr 8. Science. 2022. PMID: 35389777 Free PMC article.
Noncoding events in regulatory promoter and enhancer regions frequently involved cancer-relevant genes such as BCL6, FGFR2, RAD51B, SMC6, TERT, and XBP1 and represent possible drivers. Unlike most noncoding regulatory events, XBP1 mutations primarily accumulated outside th …
Noncoding events in regulatory promoter and enhancer regions frequently involved cancer-relevant genes such as BCL6, FGFR2, RAD51B, S …
Selection of Fusarium Trichothecene Toxin Genes for Molecular Detection Depends on TRI Gene Cluster Organization and Gene Function.
Villafana RT, Ramdass AC, Rampersad SN. Villafana RT, et al. Toxins (Basel). 2019 Jan 14;11(1):36. doi: 10.3390/toxins11010036. Toxins (Basel). 2019. PMID: 30646506 Free PMC article. Review.
Due to the challenges of inducing trichothecene production by Fusarium isolates in vitro for subsequent chemical analysis, PCR assays using gene-specific primers, either singly or in combination, designed against specific genes of the trichothecene gene cluster of multiple …
Due to the challenges of inducing trichothecene production by Fusarium isolates in vitro for subsequent chemical analysis, PCR assays using …
Strong Constraint on Human Genes Escaping X-Inactivation Is Modulated by their Expression Level and Breadth in Both Sexes.
Slavney A, Arbiza L, Clark AG, Keinan A. Slavney A, et al. Mol Biol Evol. 2016 Feb;33(2):384-93. doi: 10.1093/molbev/msv225. Epub 2015 Oct 22. Mol Biol Evol. 2016. PMID: 26494842 Free PMC article.
Another potential driver of this signal is selection for high and/or broad gene expression in both sexes, which are strong predictors of reduced nucleotide substitution rates in mammalian genes. Here, we compared purifying selection and gene expression patterns of human XC …
Another potential driver of this signal is selection for high and/or broad gene expression in both sexes, which are strong predictors of red …
Identifying novel genes contributing to asthma pathogenesis.
Holloway JW, Koppelman GH. Holloway JW, et al. Curr Opin Allergy Clin Immunol. 2007 Feb;7(1):69-74. doi: 10.1097/ACI.0b013e328013d51b. Curr Opin Allergy Clin Immunol. 2007. PMID: 17218814 Review.
RECENT FINDINGS: Many hundreds of studies have been published investigating the association of genetic polymorphisms in candidate genes with asthma. These genes were selected on the basis of the gene's product known involvement in the disease process. …
RECENT FINDINGS: Many hundreds of studies have been published investigating the association of genetic polymorphisms in candidate genes …
Trade-offs among transcription elongation rate, number, and duration of ubiquitous pauses on highly transcribed bacterial genes.
Gedeon T, Davis L, Weber K, Thorenson J. Gedeon T, et al. J Bioinform Comput Biol. 2021 Oct;19(5):2150020. doi: 10.1142/S0219720021500207. Epub 2021 Aug 5. J Bioinform Comput Biol. 2021. PMID: 34353243
These effects are especially pronounced in highly transcribed genes such as ribosomal genes (rrn) in fast growing bacteria. Our model indicates that the quantity and duration of pauses reported for protein-coding genes is incompatible with the average elongat …
These effects are especially pronounced in highly transcribed genes such as ribosomal genes (rrn) in fast growing bacteria. Ou …
Regulating specificity in enhancer-promoter communication.
Galouzis CC, Furlong EEM. Galouzis CC, et al. Curr Opin Cell Biol. 2022 Apr;75:102065. doi: 10.1016/j.ceb.2022.01.010. Epub 2022 Feb 28. Curr Opin Cell Biol. 2022. PMID: 35240372 Review.
Enhancers are cis-regulatory elements that can activate transcription remotely to regulate a specific pattern of a gene's expression. Genes typically have many enhancers that are often intermingled in the loci of other genes. ...
Enhancers are cis-regulatory elements that can activate transcription remotely to regulate a specific pattern of a gene's expr …
RNA Transcript Diversity in Neuromuscular Research.
Lim WF, Rinaldi C. Lim WF, et al. J Neuromuscul Dis. 2023;10(4):473-482. doi: 10.3233/JND-221601. J Neuromuscul Dis. 2023. PMID: 37182892 Free PMC article. Review.
Three decades since the Human Genome Project began, scientists have now identified more then 25,000 protein coding genes in the human genome. The vast majority of the protein coding genes (> 90%) are multi-exonic, with the coding DNA being interrupted by intronic …
Three decades since the Human Genome Project began, scientists have now identified more then 25,000 protein coding genes in the human …
Phylogenetic analysis of achaete-scute complex genes in metazoans.
Wang Y, Wang GD, He QL, Luo ZP, Yang L, Yao Q, Chen KP. Wang Y, et al. Mol Genet Genomics. 2020 May;295(3):591-606. doi: 10.1007/s00438-020-01648-y. Epub 2020 Jan 31. Mol Genet Genomics. 2020. PMID: 32006176
Various metazoan species have greatly different numbers of genes in ASCa, ASCb and ASCc families. To explore evolutionary mechanisms of metazoan ASC genes, Blast (basic local alignment search tool) searches and phylogenetic analyses were conducted to identify ASC …
Various metazoan species have greatly different numbers of genes in ASCa, ASCb and ASCc families. To explore evolutionary mechanisms …
Assembling seed dormancy genes into a system identified their effects on seedbank longevity in weedy rice.
Pipatpongpinyo W, Korkmaz U, Wu H, Kena A, Ye H, Feng J, Gu XY. Pipatpongpinyo W, et al. Heredity (Edinb). 2020 Jan;124(1):135-145. doi: 10.1038/s41437-019-0253-8. Epub 2019 Aug 7. Heredity (Edinb). 2020. PMID: 31391557 Free PMC article.
SD7-1 (identical to the pericarp color gene Rc) played a major role in regulating seedbank longevity when interacted with the other SD gene(s). This research provided evidence that natural genes controlling SD are involved in regulation of soil seedbank longe …
SD7-1 (identical to the pericarp color gene Rc) played a major role in regulating seedbank longevity when interacted with the other SD ge …
XA4C: eXplainable representation learning via Autoencoders revealing Critical genes.
Li Q, Yu Y, Kossinna P, Lun T, Liao W, Zhang Q. Li Q, et al. PLoS Comput Biol. 2023 Oct 2;19(10):e1011476. doi: 10.1371/journal.pcbi.1011476. eCollection 2023 Oct. PLoS Comput Biol. 2023. PMID: 37782668 Free PMC article.
., the "latent variables" in an autoencoder, are difficult to interpret, not to mention prioritizing essential genes for functional follow-up. In contrast, in traditional analyses, one may identify important genes such as Differentially Expressed (DiffEx), Different …
., the "latent variables" in an autoencoder, are difficult to interpret, not to mention prioritizing essential genes for functional f …
1,870,023 results
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