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Impaired catabolism of free oligosaccharides due to MAN2C1 variants causes a neurodevelopmental disorder.
Maia N, Potelle S, Yildirim H, Duvet S, Akula SK, Schulz C, Wiame E, Gheldof A, O'Kane K, Lai A, Sermon K, Proisy M, Loget P, Attié-Bitach T, Quelin C, Fortuna AM, Soares AR, de Brouwer APM, Van Schaftingen E, Nassogne MC, Walsh CA, Stouffs K, Jorge P, Jansen AC, Foulquier F. Maia N, et al. Am J Hum Genet. 2022 Feb 3;109(2):345-360. doi: 10.1016/j.ajhg.2021.12.010. Epub 2022 Jan 18. Am J Hum Genet. 2022. PMID: 35045343 Free PMC article.
Free oligosaccharides (fOSs) are soluble oligosaccharide species generated during N-glycosylation of proteins. ...We further demonstrate that MAN2C1 variants lead to accumulation and delay in the processing of fOSs in proband-derived cells. These results emphasize t …
Free oligosaccharides (fOSs) are soluble oligosaccharide species generated during N-glycosylation of proteins. ...We further demonstr …
Discovery and Enzymatic Screening of Genome-Mined Microbial Levanases to Produce Second-Generation β-(2,6)-Fructooligosaccharides: Catalytic Properties.
Chen L, Hill A, Petit JL, Mariage A, de Berardinis V, Karboune S. Chen L, et al. ACS Chem Biol. 2023 Mar 17;18(3):465-475. doi: 10.1021/acschembio.2c00728. Epub 2023 Feb 24. ACS Chem Biol. 2023. PMID: 36826427
Evidence suggests that beta-(2,6)-levan-type fructooligosaccharides (FOSs) possess higher prebiotic potential and selectivity than their beta-(2,1)-inulin-type counterparts. ...The identification of these novel levanases is expected to contribute to the production of levan …
Evidence suggests that beta-(2,6)-levan-type fructooligosaccharides (FOSs) possess higher prebiotic potential and selectivity than th …
Ontogenetic effects of diet during early development on growth performance, myosin mRNA expression and metabolic enzyme activity in Atlantic cod juveniles reared at different salinities.
Koedijk RM, Le François NR, Blier PU, Foss A, Folkvord A, Ditlecadet D, Lamarre SG, Stefansson SO, Imsland AK. Koedijk RM, et al. Comp Biochem Physiol A Mol Integr Physiol. 2010 May;156(1):102-9. doi: 10.1016/j.cbpa.2010.01.007. Epub 2010 Jan 20. Comp Biochem Physiol A Mol Integr Physiol. 2010. PMID: 20096365