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1975 1
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Page 1
Microwave-assisted synthesis of HYNIC protected analogue for 99mTc labeled antibody.
García MF, Calzada V, Camacho X, Goicochea E, Gambini JP, Quinn TP, Porcal W, Cabral P. García MF, et al. Curr Radiopharm. 2014;7(2):84-90. doi: 10.2174/1874471007666141128160449. Curr Radiopharm. 2014. PMID: 25429778 Review.
We described herein a simple and efficient microwave assisted synthesis of HYNIC analogues. Two different activated esters of HYNIC, the hydrazine protected with a trifluoroacetyl group (5) and the free hydrazine (6) were conjugated to the monoclonal antibody Nimotuzumab. …
We described herein a simple and efficient microwave assisted synthesis of HYNIC analogues. Two different activated esters of HYNIC, …
177Lu-DOTA-Bevacizumab: Radioimmunotherapy Agent for Melanoma.
Camacho X, Calzada V, Fernandez M, Alonso O, Chammas R, Riva E, Gambini JP, Cabral P. Camacho X, et al. Curr Radiopharm. 2017;10(1):21-28. doi: 10.2174/1874471009666161010155246. Curr Radiopharm. 2017. PMID: 27748184
OBJECTIVE: To radiolabel Bevacizumab with 177-Lutetium as a potential radioimmunotherapy agent for melanoma. METHODS: Bevacizumab was derivatized with DOTA-NHS-ester at 4 C for 18 h. DOTABevacizumab was radiolabeled with 177LuCl3 (15 MBq/mg) at 37 C for 1 h. ...
OBJECTIVE: To radiolabel Bevacizumab with 177-Lutetium as a potential radioimmunotherapy agent for melanoma. METHODS: Bevacizumab was deriva …
Chain Cleavage of Bioinspired Bacterial Membranes Photoinduced by Eosin Decyl Ester.
Moreira LG, Almeida AM Jr, Camacho SA, Estevão BM, Oliveira ON Jr, Aoki PHB. Moreira LG, et al. Langmuir. 2020 Aug 18;36(32):9578-9585. doi: 10.1021/acs.langmuir.0c01600. Epub 2020 Aug 4. Langmuir. 2020. PMID: 32672975
Photoinduced damage in the lipid envelope may already induce microbial inactivation, which requires PS capable of easily penetrating into the membrane. Herein, we report on the insertion of the PS eosin decyl ester (EosDec) into Langmuir films of 1,2-dioleoyl-sn-glycero-3- …
Photoinduced damage in the lipid envelope may already induce microbial inactivation, which requires PS capable of easily penetrating into th …
Carboxyl ester hydrolases production and growth of a halophilic archaeon, Halobacterium sp. NRC-1.
Camacho RM, Mateos-Díaz JC, Diaz-Montaño DM, González-Reynoso O, Córdova J. Camacho RM, et al. Extremophiles. 2010 Jan;14(1):99-106. doi: 10.1007/s00792-009-0291-x. Epub 2009 Dec 2. Extremophiles. 2010. PMID: 19957092
The haloarchaeon synthesized a carboxyl ester hydrolase, confirming the genomic prediction. This enzymatic activity was intracellularly produced as a growth-associated metabolite. Esterase activity was assayed using different p-nitrophenyl-esters and triacyl-glyceri …
The haloarchaeon synthesized a carboxyl ester hydrolase, confirming the genomic prediction. This enzymatic activity was intracellular …
Modulating photochemical reactions in Langmuir monolayers of Escherichia coli lipid extract with the binding mechanisms of eosin decyl ester and toluidine blue-O photosensitizers.
Moreira LG, Almeida AM Jr, Nield T, Camacho SA, Aoki PHB. Moreira LG, et al. J Photochem Photobiol B. 2021 May;218:112173. doi: 10.1016/j.jphotobiol.2021.112173. Epub 2021 Mar 11. J Photochem Photobiol B. 2021. PMID: 33799010
Herein, Langmuir monolayers of Escherichia coli lipid extract were built to determine the binding mechanisms and oxidation outcomes induced by eosin decyl ester (EosDEC) and toluidine blue-O (TBO) PSs. Surface-pressure isotherms of the E. coli monolayers were expanded upon …
Herein, Langmuir monolayers of Escherichia coli lipid extract were built to determine the binding mechanisms and oxidation outcomes induced …
Development of a rapid assay for β-etherase activity using a novel chromogenic substrate.
Romero-Soto IC, Rodríguez JA, Armenta-Pérez VP, Martínez-Pérez RB, Camacho-Ruiz RM, Alencar Menezes LR, Sassaki GL, Santana-Filho A, Camacho-Ruiz MA. Romero-Soto IC, et al. Talanta. 2024 Apr 1;270:125501. doi: 10.1016/j.talanta.2023.125501. Epub 2023 Dec 3. Talanta. 2024. PMID: 38091749
A novel method for quantifying beta-etherase activity was developed based on the beta-ester bond formation between a chromophore and acetovainillone. The chromogenic substrate beta-(rho-nitrophenoxy)-alpha-acetovanillone (PNPAV), was chemically synthesized. ...
A novel method for quantifying beta-etherase activity was developed based on the beta-ester bond formation between a chromophore and …
Technetium-99m- or Cy7-Labeled Rituximab as an Imaging Agent for Non-Hodgkin Lymphoma.
Camacho X, Machado CL, García MF, Gambini JP, Banchero A, Fernández M, Oddone N, Bertolini Zanatta D, Rosal C, Buchpiguel CA, Chammas R, Riva E, Cabral P. Camacho X, et al. Oncology. 2017;92(4):229-242. doi: 10.1159/000452419. Epub 2017 Feb 15. Oncology. 2017. PMID: 28196364
METHODS: Rituximab was derivatized with the trifluoroacetyl hydrazino protected form of succinimidyl ester of HYNIC and radiolabeled with 99mTc. Radiochemical stability and in vitro cell assays were evaluated. ...
METHODS: Rituximab was derivatized with the trifluoroacetyl hydrazino protected form of succinimidyl ester of HYNIC and radiolabeled …
Solid-state NMR spectroscopy identifies three classes of lipids in Cryptococcus neoformans melanized cell walls and whole fungal cells.
Chrissian C, Camacho E, Kelly JE, Wang H, Casadevall A, Stark RE. Chrissian C, et al. J Biol Chem. 2020 Oct 30;295(44):15083-15096. doi: 10.1074/jbc.RA120.015201. Epub 2020 Aug 28. J Biol Chem. 2020. PMID: 32859751 Free PMC article.
The lipid profiles were remarkably similar in whole C. neoformans cells, grown under either melanizing or nonmelanizing conditions; triglycerides (TGs), sterol esters (SEs), and polyisoprenoids (PPs) were the major constituents. ...
The lipid profiles were remarkably similar in whole C. neoformans cells, grown under either melanizing or nonmelanizing conditions; triglyce …
Purification of a carboxypeptidase B-like enzyme from the starfish Dermasterias imbricata.
Ferrell RE, Camacho Z, Kitto GB. Ferrell RE, et al. Biochim Biophys Acta. 1975 Mar 28;386(1):260-9. doi: 10.1016/0005-2795(75)90267-6. Biochim Biophys Acta. 1975. PMID: 236021
A carboxypeptidase B-like enzyme which catalyses the hydrolysis of synthetic esters of lysine and arginine has been isolated from the starfish Dermasterias imbricata. ...
A carboxypeptidase B-like enzyme which catalyses the hydrolysis of synthetic esters of lysine and arginine has been isolated from the …
22 results