Impaired neutralizing antibody efficacy of tixagevimab-cilgavimab 150+150 mg as pre-exposure prophylaxis against Omicron BA.5. A real-world experience in booster vaccinated immunocompromised patients.
Schiaroli E, Gidari A, Brachelente G, Bicchieraro G, Spaccapelo R, Bastianelli S, Pierucci S, Busti C, Pallotto C, Malincarne L, Camilloni B, Falcinelli F, De Socio GV, Villa A, Mencacci A, Francisci D.
Schiaroli E, et al.
J Clin Virol. 2023 Nov;168:105584. doi: 10.1016/j.jcv.2023.105584. Epub 2023 Sep 17.
J Clin Virol. 2023.
PMID: 37778220
Free article.
RESULTS: At baseline, 35.2%, 37.02%, and 32.5% of booster vaccinated patients exhibited undetectable levels of anti-S and anti-RBD IgG antibodies such as NT(90)-Abs titres against A20.EU1. ...Four patients (7.5%) had a severe acute respiratory syndrome coronavirus 2 (SARS- …
RESULTS: At baseline, 35.2%, 37.02%, and 32.5% of booster vaccinated patients exhibited undetectable levels of anti-S and anti-RBD Ig …