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2003 1
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2008 3
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2014 1
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2016 5
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2023 16
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68 results

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Page 1
Risk prediction of hepatobiliary and pancreatic cancers in elderly Chinese: The Dongfeng-Tongji cohort.
Lyu J, Guan X, Zhou Y, Guo H, Cheng S, Wang C. Lyu J, et al. J Evid Based Med. 2023 Mar;16(1):39-49. doi: 10.1111/jebm.12516. Epub 2023 Mar 7. J Evid Based Med. 2023. PMID: 36880416
The objective of the study is to build cost-effective models to identify high-risk individuals for early diagnosis and substantially to reduce the burden of HBP cancers. METHODS: Based on the prospective Dongfeng-Tongji cohort with 6 years follow-up, we identified 162 inci …
The objective of the study is to build cost-effective models to identify high-risk individuals for early diagnosis and substantially to redu …
Associations between multiple metals exposure and biological aging: Evidence from the Dongfeng-Tongji cohort.
Wang C, Hong S, Guan X, Xiao Y, Fu M, Meng H, Feng Y, Zhou Y, Cao Q, Yuan F, Liu C, Zhong G, You Y, Wu T, Yang H, Zhang X, He M, Wu T, Guo H. Wang C, et al. Sci Total Environ. 2023 Feb 25;861:160596. doi: 10.1016/j.scitotenv.2022.160596. Epub 2022 Dec 2. Sci Total Environ. 2023. PMID: 36464054
Metal exposures are linked with many health effects, but have poorly understood associations with aging. In this study, a total of 33,916 participants from the Dongfeng-Tongji cohort were included to establish biological age (BA) predictors by using recent advanced algorit …
Metal exposures are linked with many health effects, but have poorly understood associations with aging. In this study, a total of 33,916 pa …
Circulating white blood cells and lung function impairment: the observational studies and Mendelian randomization analysis.
Wu X, Wang C, Li H, Meng H, Jie J, Fu M, Bai Y, Li G, Wei W, Feng Y, Li M, Guan X, He M, Zhang X, Guo H. Wu X, et al. Ann Med. 2021 Dec;53(1):1118-1128. doi: 10.1080/07853890.2021.1948603. Ann Med. 2021. PMID: 34259107 Free PMC article.
METHODS: The 19,159 participants from NHANES 2011-2012 (n = 3570), coke-oven workers (COW, n = 1762) and Dongfeng-Tongji (DFTJ, n = 13,827) cohorts were included in the observational studies. ...
METHODS: The 19,159 participants from NHANES 2011-2012 (n = 3570), coke-oven workers (COW, n = 1762) and Dongfeng-Tongji (DFTJ, n = 1 …
DNA methylation aging signatures of multiple metals exposure and their mediation effects in metal-associated mortality: Evidence from the Dongfeng-Tongji cohort study.
Wang C, Zhong G, Liu C, Hong S, Guan X, Xiao Y, Fu M, Zhou Y, You Y, Wu T, Zhao H, Wang Y, Chen S, Zhang Y, Wang C, Guo H. Wang C, et al. J Hazard Mater. 2024 Mar 5;465:133200. doi: 10.1016/j.jhazmat.2023.133200. Epub 2023 Dec 10. J Hazard Mater. 2024. PMID: 38113735
Humans were exposed to multiple metals, but the impact of metals on DNA methylation-age (DNAm-age), a well-recognized aging measure, remains inconclusive. This study included 2942 participants from the Dongfeng-Tongji cohort. We detected their plasma concentrations of 23 m …
Humans were exposed to multiple metals, but the impact of metals on DNA methylation-age (DNAm-age), a well-recognized aging measure, remains …
A machine learning-based biological aging prediction and its associations with healthy lifestyles: the Dongfeng-Tongji cohort.
Wang C, Guan X, Bai Y, Feng Y, Wei W, Li H, Li G, Meng H, Li M, Jie J, Fu M, Wu X, He M, Zhang X, Yang H, Lu Y, Guo H. Wang C, et al. Ann N Y Acad Sci. 2022 Jan;1507(1):108-120. doi: 10.1111/nyas.14685. Epub 2021 Sep 3. Ann N Y Acad Sci. 2022. PMID: 34480349
The 14,848 participants with the available information of multisystem measurements from the Dongfeng-Tongji cohort were used to estimate BA. We developed a composite BA predictor showing a high correlation with chronological age (CA) (r = 0.82) by using an extreme gradient …
The 14,848 participants with the available information of multisystem measurements from the Dongfeng-Tongji cohort were used to estim …
Aberrant JAK-STAT signaling-mediated chromatin remodeling impairs the sensitivity of NK/T-cell lymphoma to chidamide.
Chen J, Zuo Z, Gao Y, Yao X, Guan P, Wang Y, Li Z, Liu Z, Hong JH, Deng P, Chan JY, Cheah DMZ, Lim J, Chai KXY, Chia BKH, Pang JWL, Koh J, Huang D, He H, Sun Y, Liu L, Liu S, Huang Y, Wang X, You H, Saraf SA, Grigoropoulos NF, Li X, Bei J, Kang T, Lim ST, Teh BT, Huang H, Ong CK, Tan J. Chen J, et al. Clin Epigenetics. 2023 Feb 6;15(1):19. doi: 10.1186/s13148-023-01436-6. Clin Epigenetics. 2023. PMID: 36740715 Free PMC article. Clinical Trial.
Multiple metals exposure and blood mitochondrial DNA copy number: A cross-sectional study from the Dongfeng-Tongji cohort.
Fu M, Wang C, Hong S, Guan X, Meng H, Feng Y, Xiao Y, Zhou Y, Liu C, Zhong G, You Y, Wu T, Yang H, Zhang X, He M, Guo H. Fu M, et al. Environ Res. 2023 Jan 1;216(Pt 1):114509. doi: 10.1016/j.envres.2022.114509. Epub 2022 Oct 5. Environ Res. 2023. PMID: 36208786
METHODS: This study involved 1399 randomly selected subcohort participants from the Dongfeng-Tongji cohort. The blood mtDNAcn and plasma levels of 23 metals were determined by using quantitative real-time polymerase chain reaction (qPCR) and inductively coupled plasma mass …
METHODS: This study involved 1399 randomly selected subcohort participants from the Dongfeng-Tongji cohort. The blood mtDNAcn and pla …
68 results