Phytoantitoxin resveratrol, which belongs to polyphenol, is a kind of phytoestrogen, and protects the cardiovascular system against ischemic-reperfusion injury and promotion of vasorelaxation, protects and maintains the intact endothelium, exhibits antiatherosclerotic properties inhibits the LDL oxidation, suppress the platelet aggregation and exhibits estrogen like action. The purpose of this article is to review the mechanisms of about mentioned effects. (Ref. 30.).