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Phosphine-induced oxidative damage in rats: attenuation by melatonin.
Hsu C, Han B, Liu M, Yeh C, Casida JE. Hsu C, et al. Free Radic Biol Med. 2000 Feb 15;28(4):636-42. doi: 10.1016/s0891-5849(99)00277-4. Free Radic Biol Med. 2000. PMID: 10719245
Thirty min later the brain, liver, and lung were analyzed for glutathione (GSH) levels and lipid peroxidation (as malondialdehyde and 4-hydroxyalkenals) and brain and lung for 8-hydroxydeoxyguanosine (8-OH-dGuo) in DNA. PH(3) caused a significant decrease in GSH concentrat …
Thirty min later the brain, liver, and lung were analyzed for glutathione (GSH) levels and lipid peroxidation (as malondialdehyde and 4-hydr …
Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis in A/J mice by green tea and its major polyphenol as antioxidants.
Xu Y, Ho CT, Amin SG, Han C, Chung FL. Xu Y, et al. Cancer Res. 1992 Jul 15;52(14):3875-9. Cancer Res. 1992. PMID: 1617663
While green tea and EGCG exerted little effect on the formation of O6-methylguanine, a critical DNA lesion in NNK lung tumorigenesis, both treatments suppressed the increase of 8-OH-dGuo levels in mouse lung DNA. The inhibition of 8-OH-dGuo formation in lung DNA by …
While green tea and EGCG exerted little effect on the formation of O6-methylguanine, a critical DNA lesion in NNK lung tumorigenesis, both t …