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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 2
1997 1
1999 1
2000 1
2001 1
2002 1
2004 1
2005 1
2006 1
2007 1
2008 2
2009 8
2010 7
2011 6
2012 7
2013 12
2014 12
2015 12
2016 18
2017 20
2018 20
2019 27
2020 31
2021 36
2022 34
2023 32
2024 19

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280 results

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Page 1
Dexmedetomidine attenuates myocardial ischemia/reperfusion-induced ferroptosis via AMPK/GSK-3β/Nrf2 axis.
Wang Z, Yao M, Jiang L, Wang L, Yang Y, Wang Q, Qian X, Zhao Y, Qian J. Wang Z, et al. Biomed Pharmacother. 2022 Oct;154:113572. doi: 10.1016/j.biopha.2022.113572. Epub 2022 Aug 18. Biomed Pharmacother. 2022. PMID: 35988428 Free article.
Dex significantly increased the expression levels of Nrf2, SLC7A11, and GPX4. However, inhibition of Nrf2 by ML385 blunted the protective effect of Dex in HR-treated H9c2 cells. Inhibition of AMPK with a specific inhibitor or siRNA decreased the expression levels of …
Dex significantly increased the expression levels of Nrf2, SLC7A11, and GPX4. However, inhibition of Nrf2 by ML385 blunted the protec …
The Role and Mechanism of SIRT1 in Resveratrol-regulated Osteoblast Autophagy in Osteoporosis Rats.
Yang X, Jiang T, Wang Y, Guo L. Yang X, et al. Sci Rep. 2019 Dec 5;9(1):18424. doi: 10.1038/s41598-019-44766-3. Sci Rep. 2019. PMID: 31804494 Free PMC article.
On the other hand, resveratrol treatment increased the SIRT1 activity, LC3 and Beclin-1 mRNA expression in the dexamethasone (DEX)-treated osteoblasts. More mitophagosomes were observed in the DEX-treated osteoblasts with resveratrol. Meanwhile, the TOM20, Hsp60, p- …
On the other hand, resveratrol treatment increased the SIRT1 activity, LC3 and Beclin-1 mRNA expression in the dexamethasone (DEX)-tr …
Targeting BCL-2 with venetoclax and dexamethasone in patients with relapsed/refractory t(11;14) multiple myeloma.
Kaufman JL, Gasparetto C, Schjesvold FH, Moreau P, Touzeau C, Facon T, Boise LH, Jiang Y, Yang X, Dunbar F, Vishwamitra D, Unger S, Macartney T, Pesko J, Yu Y, Salem AH, Ross JA, Hong WJ, Maciag PC, Pauff JM, Kumar S. Kaufman JL, et al. Am J Hematol. 2021 Apr 1;96(4):418-427. doi: 10.1002/ajh.26083. Epub 2021 Jan 19. Am J Hematol. 2021. PMID: 33368455 Free PMC article. Clinical Trial.
Patients in both phases received VenDex (oral Ven 800 mg/day + oral Dex 40 mg [20 mg for patients 75 years] on days 1, 8, and 15, per 21-day cycle). ...
Patients in both phases received VenDex (oral Ven 800 mg/day + oral Dex 40 mg [20 mg for patients 75 years] on days 1, 8, and 15, per …
Dexamethasone induces ferroptosis via P53/SLC7A11/GPX4 pathway in glucocorticoid-induced osteonecrosis of the femoral head.
Sun F, Zhou JL, Liu ZL, Jiang ZW, Peng H. Sun F, et al. Biochem Biophys Res Commun. 2022 Apr 30;602:149-155. doi: 10.1016/j.bbrc.2022.02.112. Epub 2022 Mar 1. Biochem Biophys Res Commun. 2022. PMID: 35276555
The results in vitro experiments show that Dex can induce MC3T3-E1 cells ferroptosis by down-regulating SLC7A11. ...Thus, this study demonstrated that Dex induces MC3T3-E1cells ferroptosis via p53/SLC7A11/GPX4 pathway. ...
The results in vitro experiments show that Dex can induce MC3T3-E1 cells ferroptosis by down-regulating SLC7A11. ...Thus, this study …
Perioperative dexmedetomidine administration to prevent delirium in adults after non-cardiac surgery: A systematic review and meta-analysis.
Qin C, Jiang Y, Lin C, Li A, Liu J. Qin C, et al. J Clin Anesth. 2021 Oct;73:110308. doi: 10.1016/j.jclinane.2021.110308. Epub 2021 Apr 28. J Clin Anesth. 2021. PMID: 33930679 Review.
STUDY OBJECTIVE: To evaluate the efficacy of perioperative dexmedetomidine (DEX) administration for preventing delirium in adults after non-cardiac surgery. ...In addition, perioperative DEX administration was associated with an elevated risk of bradycardia and hypo …
STUDY OBJECTIVE: To evaluate the efficacy of perioperative dexmedetomidine (DEX) administration for preventing delirium in adults aft …
Dendrobium offificinale polysaccharides prevents glucocorticoids-induced osteoporosis by destabilizing KEAP1-NRF2 interaction.
Wang Y, Jiang Z, Deng L, Zhang G, Xu X, Alonge E, Zhang H, Guo C. Wang Y, et al. Int J Biol Macromol. 2023 Dec 31;253(Pt 1):126600. doi: 10.1016/j.ijbiomac.2023.126600. Epub 2023 Aug 29. Int J Biol Macromol. 2023. PMID: 37652317
Importantly, we found that DOP treatment significantly inhibited DEX-induced osteoporosis in two in vivo models, zebrafish and mice, while boosting osteogenic differentiation of hBMSCs exposed to DEX. ...Taken together, these results illuminate that DOP stimulates o …
Importantly, we found that DOP treatment significantly inhibited DEX-induced osteoporosis in two in vivo models, zebrafish and mice, …
PON2 blockade overcomes dexamethasone resistance in acute lymphoblastic leukemia.
Hui PY, Chen YH, Qin J, Jiang XH. Hui PY, et al. Hematology. 2022 Dec;27(1):32-42. doi: 10.1080/16078454.2021.2009643. Hematology. 2022. PMID: 34957927
RESULTS: This study was designed to identify GC resistance-associated genes by means of the transcriptome chip from the public Gene Expression Omnibus database, and preliminarily investigation of dexamethasone (DEX)-resistance mechanism in ALL. We disclosed that PON2 expre …
RESULTS: This study was designed to identify GC resistance-associated genes by means of the transcriptome chip from the public Gene Expressi …
Effects of Puerarin-Loaded Tetrahedral Framework Nucleic Acids on Osteonecrosis of the Femoral Head.
Zhao Y, Li S, Feng M, Zhang M, Liu Z, Yao Y, Zhang T, Jiang Y, Lin Y, Cai X. Zhao Y, et al. Small. 2023 Oct;19(41):e2302326. doi: 10.1002/smll.202302326. Epub 2023 Jun 14. Small. 2023. PMID: 37317020
In this study, tFNAs as Pue carriers is used and synthesized a tFNA/Pue complex (TPC) that exhibited better stability, biocompatibility, and tissue utilization than free Pue. A dexamethasone (DEX)-treated BMSC model in vitro and a methylprednisolone (MPS)-induced ONFH mode …
In this study, tFNAs as Pue carriers is used and synthesized a tFNA/Pue complex (TPC) that exhibited better stability, biocompatibility, and …
Dexamethasone and MicroRNA-204 Inhibit Corneal Neovascularization.
Zhang X, Wang G, Wang Q, Jiang R BS. Zhang X, et al. Mil Med. 2024 Jan 23;189(1-2):374-378. doi: 10.1093/milmed/usac260. Mil Med. 2024. PMID: 36043264
The mice were randomly divided into five groups: normal control (Ctrl), alkali burn-induced corneal injury (Alkali), alkali burn + Dex (Dex), alkali burn + negative control (NTC), and alkali burn + miR-204 agomir (miR-204). Subconjunctival injection of NTC, Dex …
The mice were randomly divided into five groups: normal control (Ctrl), alkali burn-induced corneal injury (Alkali), alkali burn + Dex …
Tetrahedral Framework Nucleic Acids Inhibit Muscular Mitochondria-Mediated Apoptosis and Ameliorate Muscle Atrophy in Sarcopenia.
Yu X, Wang Y, Ran L, Jiang Y, Chen M, Du H, Zhang Y, Wu D, Xiang X, Zhang J, Jiang N, He H, Song Y, Xiang Z, He C, Zhou Z, Zeng J, Xiang Y, Huang SS, Lin Y. Yu X, et al. Nano Lett. 2023 Sep 27;23(18):8816-8826. doi: 10.1021/acs.nanolett.3c01502. Epub 2023 Jul 17. Nano Lett. 2023. PMID: 37459451
Results from muscular biophysiological characteristics demonstrated significant improvement in muscle function and endurance in the aged mouse model, and histologic examinations also showed beneficial morphological changes in muscle fibers. In vitro, DEX-induced sarcopenic …
Results from muscular biophysiological characteristics demonstrated significant improvement in muscle function and endurance in the aged mou …
280 results