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Danhong Injection and Trimetazidine Protect Cardiomyocytes and Enhance Calcium Handling after Myocardial Infarction.
Zhang J, Shi X, Gao J, Zhou R, Guo F, Zhang Y, Fan F, Zhai Q, Sun M, Yang H. Zhang J, et al. Evid Based Complement Alternat Med. 2021 Jan 15;2021:2480465. doi: 10.1155/2021/2480465. eCollection 2021. Evid Based Complement Alternat Med. 2021. PMID: 33510801 Free PMC article.
However, there is no effective treatment for MI. In this study, trimetazidine (TMZ) and Danhong injection (DHI), representing western medicine and traditional Chinese medicine for MI, were used as tools to identify vital processes in alleviating MI injury. ...
However, there is no effective treatment for MI. In this study, trimetazidine (TMZ) and Danhong injection (DHI), representing western …
Effects of Danhong Injection on platelet aggregation in hyperlipidemia rats.
Fan H, Li M, Yu L, Jin W, Yang J, Zhang Y, Wan H. Fan H, et al. J Ethnopharmacol. 2018 Feb 15;212:67-73. doi: 10.1016/j.jep.2017.10.017. Epub 2017 Oct 21. J Ethnopharmacol. 2018. PMID: 29066405
ETHNOPHARMACOLOGICAL RELEVANCE: Danhong Injection (DHI), a Chinese medical product extracted from Radix et Rhizoma Salviae Miltiorrhizae (Salvia miltiorrhiza Bge., Labiatae, Danshen in Chinese) and Flos Carthami (Carthamus tinctorius L., Compositae, Honghua in Chinese), ha …
ETHNOPHARMACOLOGICAL RELEVANCE: Danhong Injection (DHI), a Chinese medical product extracted from Radix et Rhizoma Salviae Miltiorrhi …
Danhong injection reduces vascular remodeling and up-regulates the Kallikrein-kinin system in spontaneously hypertensive rats.
Yang X, Orgah J, Wang D, Fan G, Jingyang H, Han J, Qin G, Gao X, Zhu Y. Yang X, et al. Sci Rep. 2017 Jun 27;7(1):4308. doi: 10.1038/s41598-017-04661-1. Sci Rep. 2017. PMID: 28655904 Free PMC article.
Although Danhong injection (DHI) is one of the most prescribed cardiovascular medicines in China, its therapeutic indications and mechanisms remain partially defined. ...
Although Danhong injection (DHI) is one of the most prescribed cardiovascular medicines in China, its therapeutic indications and mec …
Danhong Injection Reversed Cardiac Abnormality in Brain-Heart Syndrome via Local and Remote beta-Adrenergic Receptor Signaling.
Orgah JO, Yu J, Zhao T, Wang L, Yang M, Zhang Y, Fan G, Zhu Y. Orgah JO, et al. Front Pharmacol. 2018 Jul 3;9:692. doi: 10.3389/fphar.2018.00692. eCollection 2018. Front Pharmacol. 2018. PMID: 30018549 Free PMC article.
We hypothesize that considering the established efficacy for both ischemic stroke and myocardial infarction (MI), Danhong injection (DHI), a multicomponent Chinese patent medicine, may have a dual pharmacological potential for treating the brain-heart syndrome caused by ce …
We hypothesize that considering the established efficacy for both ischemic stroke and myocardial infarction (MI), Danhong injection ( …
Danhong Injection Enhances the Therapeutic Efficacy of Mesenchymal Stem Cells in Myocardial Infarction by Promoting Angiogenesis.
Chen J, Wei J, Huang Y, Ma Y, Ni J, Li M, Zhu Y, Gao X, Fan G. Chen J, et al. Front Physiol. 2018 Jul 26;9:991. doi: 10.3389/fphys.2018.00991. eCollection 2018. Front Physiol. 2018. PMID: 30093864 Free PMC article.
Surrounding the myocardial infarct area, we performed a multi-point MSC transplantation and administered in conjunction with Danhong injection, which is mainly used for the treatment of MI. Our results showed that the MSC survival rate and cardiac function were improved si …
Surrounding the myocardial infarct area, we performed a multi-point MSC transplantation and administered in conjunction with Danhong …
Danhong Injection Protects Against Hypertension-Induced Renal Injury Via Down-Regulation of Myoglobin Expression in Spontaneously Hypertensive Rats.
Owoicho Orgah J, Wang M, Yang X, Wang Z, Wang D, Zhang Q, Fan G, Han J, Qin G, Gao X, Zhu Y. Owoicho Orgah J, et al. Kidney Blood Press Res. 2018;43(1):12-24. doi: 10.1159/000486735. Epub 2018 Jan 23. Kidney Blood Press Res. 2018. PMID: 29393225 Free article.
Currently, single-target anti-hypertensive drugs are not designed for high blood pressure-related organ damages. Danhong injection (DHI), made from the aqueous extracts of Radix Salviae miltiorrhizae and Flos Carthamus tinctorius, has various pharmacological effects, inclu …
Currently, single-target anti-hypertensive drugs are not designed for high blood pressure-related organ damages. Danhong injection (D …
Danhong injection in the treatment of idiopathic pulmonary fibrosis: A protocol for systematic review and meta-analysis.
Lan Y, Wu D, Jin Y, Shui M, Fan X. Lan Y, et al. Medicine (Baltimore). 2020 Sep 11;99(37):e22016. doi: 10.1097/MD.0000000000022016. Medicine (Baltimore). 2020. PMID: 32925734 Free PMC article.
BACKGROUND: Many studies have reported that the effects of danhong injection on idiopathic pulmonary fibrosis. However, its effects are still not well understood. The aim of this study is to assess the effects of danhong injection in the management of idiopathic pul …
BACKGROUND: Many studies have reported that the effects of danhong injection on idiopathic pulmonary fibrosis. However, its effects a …
Danhong injection protects cardiomyocytes against hypoxia/reoxygenation- and H2O2-induced injury by inhibiting mitochondrial permeability transition pore opening.
Duan ZZ, Li YH, Li YY, Fan GW, Chang YX, Yu B, Gao XM. Duan ZZ, et al. J Ethnopharmacol. 2015 Dec 4;175:617-25. doi: 10.1016/j.jep.2015.08.033. Epub 2015 Aug 29. J Ethnopharmacol. 2015. PMID: 26320687
ETHNOPHARMACOLOGICAL RELEVANCE: Danhong injection (DHI), a Chinese medical product extracted from Radix et Rhizoma Salviae Miltiorrhizae (Salvia miltiorrhiza Bge., Labiatae, Danshen in Chinese) and Flos Carthami (Carthamus tinctorius L., Compositae, Honghua in Chinese), ha …
ETHNOPHARMACOLOGICAL RELEVANCE: Danhong injection (DHI), a Chinese medical product extracted from Radix et Rhizoma Salviae Miltiorrhi …
Revealing Calcium Signaling Pathway as Novel Mechanism of Danhong Injection for Treating Acute Myocardial Infarction by Systems Pharmacology and Experiment Validation.
Guo S, Tan Y, Huang Z, Li Y, Liu W, Fan X, Zhang J, Stalin A, Fu C, Wu Z, Wang P, Zhou W, Liu X, Wu C, Jia S, Zhang J, Duan X, Wu J. Guo S, et al. Front Pharmacol. 2022 Feb 23;13:839936. doi: 10.3389/fphar.2022.839936. eCollection 2022. Front Pharmacol. 2022. PMID: 35281886 Free PMC article.
Introduction: Danhong injection (DHI) is a traditional Chinese medicine preparation commonly used in the clinical treatment of acute myocardial infarction (AMI). ...
Introduction: Danhong injection (DHI) is a traditional Chinese medicine preparation commonly used in the clinical treatment of acute …
Danhong injection attenuates cardiac injury induced by ischemic and reperfused neuronal cells through regulating arginine vasopressin expression and secretion.
Yang M, Orgah J, Zhu J, Fan G, Han J, Wang X, Zhang B, Zhu Y. Yang M, et al. Brain Res. 2016 Jul 1;1642:516-523. doi: 10.1016/j.brainres.2016.04.046. Epub 2016 Apr 20. Brain Res. 2016. PMID: 27107944
Arginine vasopressin (AVP) may exert considerable function in the relationship of brain damage and heart failure. Danhong injection (DHI) can protect both stroke and heart failure patients with good efficacy in clinics. ...
Arginine vasopressin (AVP) may exert considerable function in the relationship of brain damage and heart failure. Danhong injection ( …
23 results