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Du-Huo-Ji-Sheng-Tang and its active component Ligusticum chuanxiong promote osteogenic differentiation and decrease the aging process of human mesenchymal stem cells.
Wang JY, Chen WM, Wen CS, Hung SC, Chen PW, Chiu JH. Wang JY, et al. J Ethnopharmacol. 2017 Feb 23;198:64-72. doi: 10.1016/j.jep.2016.12.011. Epub 2016 Dec 28. J Ethnopharmacol. 2017. PMID: 28040510
AIM OF THIS STUDY: This study was designed to investigate the effects of Du-Huo-Ji-Sheng-Tang (DHJST), a Chinese herbal medicine and its active component Ligusticum chuanxiong on osteogenic differentiation and the aging process of human mesenchymal cells (hMSCs). .. …
AIM OF THIS STUDY: This study was designed to investigate the effects of Du-Huo-Ji-Sheng-Tang (DHJST), a Chinese herbal medicine and …
A Network-Based Approach to Investigate the Neuroprotective Effects and Mechanisms of Action of Huangqi-Chuanxiong and Sanleng-Ezhu Herb Pairs in the Treatment of Cerebral Ischemic Stroke.
Zhao L, Ding LD, Xia ZH, Sheng P, Shen MM, Cai ZM, Yan BC. Zhao L, et al. Front Pharmacol. 2022 Mar 23;13:844186. doi: 10.3389/fphar.2022.844186. eCollection 2022. Front Pharmacol. 2022. PMID: 35401166 Free PMC article.
Objective: We aimed to investigate the effect and mechanisms of action of two drug pairs [Huangqi-Chuanxiong and Sanleng-Ezhu Herb (HCSE)] on the treatment of ischemic stroke. ...Results: We mined the current literature and identified a new formulation of Chinese herbs for …
Objective: We aimed to investigate the effect and mechanisms of action of two drug pairs [Huangqi-Chuanxiong and Sanleng-Ezhu Herb (H …
FAEE exerts a protective effect against osteoporosis by regulating the MAPK signalling pathway.
Wang MY, An MF, Fan MS, Zhang SS, Sun ZR, Zhao YL, Xiang ZM, Sheng J. Wang MY, et al. Pharm Biol. 2022 Dec;60(1):467-478. doi: 10.1080/13880209.2022.2039216. Pharm Biol. 2022. PMID: 35180021 Free PMC article.
CONTEXT: Ferulic acid ethyl ester (FAEE) is abundant in Ligusticum chuanxiong Hort. (Apiaceae) and grains, and possesses diverse biological activities; but the effects of FAEE on osteoporosis has not been reported. ...
CONTEXT: Ferulic acid ethyl ester (FAEE) is abundant in Ligusticum chuanxiong Hort. (Apiaceae) and grains, and possesses diverse biol …
The antithrombotic effect of RSNK in blood-stasis model rats.
Dang X, Miao JJ, Chen AQ, Li P, Chen L, Liang JR, Xie RM, Zhao Y. Dang X, et al. J Ethnopharmacol. 2015 Sep 15;173:266-72. doi: 10.1016/j.jep.2015.06.030. Epub 2015 Jul 26. J Ethnopharmacol. 2015. PMID: 26216512
ETHNOPHARMACOLOGICAL RELEVANCE: Reduction of Sheng-Nao-Kang decoction (RSNK), composed of Salvia miltiorrhiza Bge., Ligusticum chuanxiong Hort., Astragalus membranaceus (Fisch.) ...Chen., is a modified traditional Chinese medicinal formula of Sheng-Nao-Kang p …
ETHNOPHARMACOLOGICAL RELEVANCE: Reduction of Sheng-Nao-Kang decoction (RSNK), composed of Salvia miltiorrhiza Bge., Ligusticum chu …
In vivo pharmacokinetic comparisons of ferulic acid and puerarin after oral administration of monomer, medicinal substance aqueous extract and Nao-De-Sheng to rats.
Ouyang Z, Zhao M, Tang J, Pan L. Ouyang Z, et al. Pharmacogn Mag. 2012 Oct;8(32):256-62. doi: 10.4103/0973-1296.103648. Pharmacogn Mag. 2012. PMID: 24082627 Free PMC article.
BACKGROUND: Nao-De-Sheng decoction (NDS), a traditional Chinese medicine (TCM) prescription containing Radix puerariae lobatae, Floscarthami, Radix et Rhizoma Notoginseng, Rhizoma chuanxiong and Fructus crataegi, is effective in the treatment of cerebral arterioscle …
BACKGROUND: Nao-De-Sheng decoction (NDS), a traditional Chinese medicine (TCM) prescription containing Radix puerariae lobatae, Flosc …
Identification and comparison of metabolites after oral administration of essential oil of Ligusticum chuanxiong or its major constituent ligustilide in rats.
Ding C, Sheng Y, Zhang Y, Zhang J, Du G. Ding C, et al. Planta Med. 2008 Nov;74(14):1684-92. doi: 10.1055/s-0028-1088309. Epub 2008 Oct 24. Planta Med. 2008. PMID: 18951338
The rhizome of Ligusticum chuanxiong Hort. is a well-known traditional Chinese medicinal herb that is widely used to treat various vascular diseases. The aims of this study were to identify and compare the metabolites in rats after the oral administration of the essential …
The rhizome of Ligusticum chuanxiong Hort. is a well-known traditional Chinese medicinal herb that is widely used to treat various va …
Analysis on Medication Rules of Chinese Medicinal Herb Formulae in Uterine Subinvolution Treatment Based on Data Mining.
Luo J, Yang M, Liu Y, Han X, Yue W. Luo J, et al. Evid Based Complement Alternat Med. 2022 Mar 31;2022:1752352. doi: 10.1155/2022/1752352. eCollection 2022. Evid Based Complement Alternat Med. 2022. PMID: 35399626 Free PMC article.
The top 6 most frequently used herbs were Angelicae Sinensis Radix (Danggui), Chuanxiong Rhizoma (Chuanxiong), Leonuri Herba (Yimucao), Persicae Semen (Taoren), Zingiberis Rhizoma Preparatum (Paojiang), and Radix Glycyrrhizae Preparata (Zhigancao). ...Herbs with war …
The top 6 most frequently used herbs were Angelicae Sinensis Radix (Danggui), Chuanxiong Rhizoma (Chuanxiong), Leonuri Herba ( …
[Comparatively evaluating effect contribution of promoting blood circulation of herb pairs containing Angelicae Sinensis Radix on Xin-Sheng-Hua granule by withdrawal analysis].
Pang HQ, Wang J, Tang YP, Wu L, Xu HQ, Jin Y, Zhu ZH, Huang SL, Sun DZ, Duan JA. Pang HQ, et al. Zhongguo Zhong Yao Za Zhi. 2016 Nov;41(21):4006-4014. doi: 10.4268/cjcmm20162120. Zhongguo Zhong Yao Za Zhi. 2016. PMID: 28929689 Chinese.
Xin-Sheng-Hua granule (XSHG) is a popular remedy commonly used in clinic for the treatment of lochiostasis after delivery. ...The orders of contribution of herb pairs containing Danggui on the formula were Danggui-Yimucao>Danggui-Chuanxiong>Danggui-Honghua> …
Xin-Sheng-Hua granule (XSHG) is a popular remedy commonly used in clinic for the treatment of lochiostasis after delivery. ...The ord …
Ligustrazine induces the colorectal cancer cells apoptosis via p53-dependent mitochondrial pathway and cell cycle arrest at the G0/G1 phase.
Bian Y, Yang L, Sheng W, Li Z, Xu Y, Li W, Zeng L. Bian Y, et al. Ann Palliat Med. 2021 Feb;10(2):1578-1588. doi: 10.21037/apm-20-288. Epub 2020 Dec 2. Ann Palliat Med. 2021. PMID: 33302638 Free article.
BACKGROUND: Ligustrazine, active ingredients extracted from the natural herb Ligusticum Chuanxiong Hort, has promising anti-tumor properties on tumor cell lines. ...
BACKGROUND: Ligustrazine, active ingredients extracted from the natural herb Ligusticum Chuanxiong Hort, has promising anti-tumor pro …
Tetramethylpyrazine inhibits agiontensin II-induced nuclear factor-kappaB activation and bone morphogenetic protein-2 downregulation in rat vascular smooth muscle cells.
Ren XY, Ruan QR, Zhu DH, Zhu M, Qu ZL, Lu J. Ren XY, et al. Sheng Li Xue Bao. 2007 Jun 25;59(3):339-44. Sheng Li Xue Bao. 2007. PMID: 17579790 Free article.
Tetramethylpyrazine (TMP), an effective component of traditional Chinese medicine Chuanxiong, is commonly used to resolve embolism. Its possible therapeutic effect against atherosclerosis has received considerable attention recently. ...
Tetramethylpyrazine (TMP), an effective component of traditional Chinese medicine Chuanxiong, is commonly used to resolve embolism. I …
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