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Addressing protein-protein interactions with small molecules: a Pro-Pro dipeptide mimic with a PPII helix conformation as a module for the synthesis of PRD-binding ligands.
Zaminer J, Brockmann C, Huy P, Opitz R, Reuter C, Beyermann M, Freund C, Müller M, Oschkinat H, Kühne R, Schmalz HG. Zaminer J, et al. Among authors: brockmann c. Angew Chem Int Ed Engl. 2010 Sep 17;49(39):7111-5. doi: 10.1002/anie.201001739. Angew Chem Int Ed Engl. 2010. PMID: 20803590 No abstract available.
Structural requirements for the ubiquitin-associated domain of the mRNA export factor Mex67 to bind its specific targets, the transcription elongation THO complex component Hpr1 and nucleoporin FXFG repeats.
Hobeika M, Brockmann C, Gruessing F, Neuhaus D, Divita G, Stewart M, Dargemont C. Hobeika M, et al. Among authors: brockmann c. J Biol Chem. 2009 Jun 26;284(26):17575-83. doi: 10.1074/jbc.M109.004374. Epub 2009 Apr 28. J Biol Chem. 2009. PMID: 19401465 Free PMC article.
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