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Lead optimization through VLAK protocol: new annelated pyrrolo-pyrimidine derivatives as antitumor agents.
Eur J Med Chem. 2012 Sep;55:375-83. doi: 10.1016/j.ejmech.2012.07.046. Epub 2012 Aug 4.
Eur J Med Chem. 2012.
PMID: 22892346
New annelated thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines, with potent anticancer activity, designed through VLAK protocol.
Lauria A, Abbate I, Patella C, Martorana A, Dattolo G, Almerico AM.
Lauria A, et al. Among authors: patella c.
Eur J Med Chem. 2013 Apr;62:416-24. doi: 10.1016/j.ejmech.2013.01.019. Epub 2013 Jan 23.
Eur J Med Chem. 2013.
PMID: 23395722
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An unexpected Dimroth rearrangement leading to annelated thieno[3,2-d][1,2,3]triazolo[1,5-a]pyrimidines with potent antitumor activity.
Lauria A, Patella C, Abbate I, Martorana A, Almerico AM.
Lauria A, et al. Among authors: patella c.
Eur J Med Chem. 2013 Jul;65:381-8. doi: 10.1016/j.ejmech.2013.05.012. Epub 2013 May 20.
Eur J Med Chem. 2013.
PMID: 23747807
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Design and synthesis of 4-substituted indolo[3,2-e][1,2,3]triazolo[1,5-a]pyrimidine derivatives with antitumor activity.
Lauria A, Patella C, Dattolo G, Almerico AM.
Lauria A, et al. Among authors: patella c.
J Med Chem. 2008 Apr 10;51(7):2037-46. doi: 10.1021/jm700964u. Epub 2008 Mar 18.
J Med Chem. 2008.
PMID: 18345607
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