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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1964 1
1966 4
1967 4
1968 4
1969 5
1970 9
1971 12
1972 8
1973 20
1974 17
1975 57
1976 70
1977 53
1978 62
1979 69
1980 111
1981 122
1982 118
1983 133
1984 144
1985 142
1986 137
1987 151
1988 179
1989 184
1990 192
1991 222
1992 208
1993 229
1994 187
1995 228
1996 247
1997 236
1998 191
1999 185
2000 230
2001 252
2002 227
2003 237
2004 230
2005 257
2006 256
2007 284
2008 385
2009 439
2010 458
2011 465
2012 456
2013 369
2014 340
2015 333
2016 275
2017 296
2018 297
2019 329
2020 333
2021 309
2022 292
2023 270
2024 102

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11,041 results

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Page 1
Mu-heavy chain disease: presentation as a benign monoclonal gammopathy.
Wahner-Roedler DL, Kyle RA. Wahner-Roedler DL, et al. Am J Hematol. 1992 May;40(1):56-60. doi: 10.1002/ajh.2830400112. Am J Hematol. 1992. PMID: 1566748 Review.
mu-Heavy chain disease (HCD) is a rare monoclonal lymphoid disorder characterized by the failure to assemble a complete IgM immunoglobulin. The mu-heavy chains analyzed to date revealed absence of the variable region and a shortened constant domain. ..
mu-Heavy chain disease (HCD) is a rare monoclonal lymphoid disorder characterized by the failure to assemble a complete IgM im
Successful treatment of mu-heavy chain disease with fludarabine monophosphate: a case report.
Yanai M, Maeda A, Watanabe N, Sugimoto N, Matsushita A, Nagai K, Oida T, Takahashi T. Yanai M, et al. Int J Hematol. 2004 Feb;79(2):174-7. doi: 10.1532/ijh97.03053. Int J Hematol. 2004. PMID: 15005347 Review.
Heavy chain diseases (HCD) are monoclonal lymphoproliferative disorders of B-cells characterized by the synthesis of truncated heavy chains without associated light chains. In patients with mu-HCD, which is a very rare form of HCD, neoplastic cells pro …
Heavy chain diseases (HCD) are monoclonal lymphoproliferative disorders of B-cells characterized by the synthesis of truncated heavy …
Morphologic features of mu-heavy-chain disease.
Courtois L, Sujobert P. Courtois L, et al. Blood. 2017 Jul 27;130(4):558. doi: 10.1182/blood-2017-04-781344. Blood. 2017. PMID: 28751360 Free article. No abstract available.
gamma- and mu-Heavy chain diseases and related disorders.
Franklin EC. Franklin EC. J Clin Pathol Suppl (Assoc Clin Pathol). 1975;6:65-71. doi: 10.1136/jcp.s1-6.1.65. J Clin Pathol Suppl (Assoc Clin Pathol). 1975. PMID: 830056 Free PMC article. Review. No abstract available.
Synthesis of immunoglobulin mu chain gene products precedes synthesis of light chains during B-lymphocyte development.
Siden E, Alt FW, Shinefeld L, Sato V, Baltimore D. Siden E, et al. Proc Natl Acad Sci U S A. 1981 Mar;78(3):1823-7. doi: 10.1073/pnas.78.3.1823. Proc Natl Acad Sci U S A. 1981. PMID: 6112749 Free PMC article.
The sizes and amounts of Ig mRNA were found to correlate with the pattern of mu and light chain protein biosynthesis. mu chain RNA species appeared earlier in gestation than light chain RNA did, and only after birth did light chain sequen …
The sizes and amounts of Ig mRNA were found to correlate with the pattern of mu and light chain protein biosynthesis. mu
Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion.
Kitamura D, Rajewsky K. Kitamura D, et al. Nature. 1992 Mar 12;356(6365):154-6. doi: 10.1038/356154a0. Nature. 1992. PMID: 1545868
Evidence from immunoglobulin-transgenic mice and immunoglobulin-gene-transfected transformed pre-B cells suggest that the membrane form of the immunoglobulin heavy (H) chain of class mu (microns), expressed from a rearranged H-chain (IgH) locus, may signal al …
Evidence from immunoglobulin-transgenic mice and immunoglobulin-gene-transfected transformed pre-B cells suggest that the membrane form of t …
Early expression of human J chain and mu chain gene in the fetal liver.
Iwase T, Saito I, Takahashi T, Chu L, Usami T, Mestecky J, Moro I. Iwase T, et al. Cell Struct Funct. 1993 Oct;18(5):297-302. doi: 10.1247/csf.18.297. Cell Struct Funct. 1993. PMID: 8168154 Free article.
The expression of J chain and mu chain genes has been investigated during human fetal ontogeny by the polymerase chain reaction performed on liver sections. ...These results indicate that J chain expression precedes that of mu chain
The expression of J chain and mu chain genes has been investigated during human fetal ontogeny by the polymerase cha
The surrogate light chain in B-cell development.
Melchers F, Karasuyama H, Haasner D, Bauer S, Kudo A, Sakaguchi N, Jameson B, Rolink A. Melchers F, et al. Immunol Today. 1993 Feb;14(2):60-8. doi: 10.1016/0167-5699(93)90060-X. Immunol Today. 1993. PMID: 8166770 Review.
The proteins encoded by the VpreB and lambda 5 genes associate with each other to form a light (L) chain-like structure, the surrogate L chain. It can form Ig-like complexes with three partners-the classical heavy (H) chain, the DHJHC mu-protein, or th …
The proteins encoded by the VpreB and lambda 5 genes associate with each other to form a light (L) chain-like structure, the surrogat …
Changes in J chain and mu chain RNA expression as a function of B cell differentiation.
Lamson G, Koshland ME. Lamson G, et al. J Exp Med. 1984 Sep 1;160(3):877-92. doi: 10.1084/jem.160.3.877. J Exp Med. 1984. PMID: 6206193 Free PMC article.
The time course of differentiative events in the pentamer IgM response was examined by following the expression of J chain and mu chain RNA and their protein products in mitogen-stimulated lymphocytes. ...The kinetics of J and mu chain RNA expre …
The time course of differentiative events in the pentamer IgM response was examined by following the expression of J chain and mu
Ultrastructural studies of human lymphoid cells. mu and J chain expression as a function of B cell differentiation.
Hajdu I, Moldoveanu Z, Cooper MD, Mestecky J. Hajdu I, et al. J Exp Med. 1983 Dec 1;158(6):1993-2006. doi: 10.1084/jem.158.6.1993. J Exp Med. 1983. PMID: 6417260 Free PMC article.
In pre-B cell lines, mu chain was seen within rough endoplasmic reticulum (RER) and the Golgi apparatus whereas J chain was not detected in these organelles. ...These results suggest that J chain expression precedes mu chain synthesis dur …
In pre-B cell lines, mu chain was seen within rough endoplasmic reticulum (RER) and the Golgi apparatus whereas J chain
11,041 results
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