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Page 1
Antimicrobial and antibiofilm activities of Casearia sylvestris extracts from distinct Brazilian biomes against Streptococcus mutans and Candida albicans.
Ribeiro SM, Fratucelli ÉDO, Bueno PCP, de Castro MKV, Francisco AA, Cavalheiro AJ, Klein MI. Ribeiro SM, et al. BMC Complement Altern Med. 2019 Nov 12;19(1):308. doi: 10.1186/s12906-019-2717-z. BMC Complement Altern Med. 2019. PMID: 31718633 Free PMC article.

RESULTS: Three extracts from the Atlantic Forest variety sylvestris (FLO/SC, GUA/CE, PRE/SP) reduced 50% (> 3 logs) S. mutans viable population (p < 0.0001 vs. vehicle), while two extracts from the same biome and variety (PAC/CE, PRE/SP) decreased 50% o

…
RESULTS: Three extracts from the Atlantic Forest variety sylvestris (FLO/SC, GUA/CE, PRE/SP) reduced 50% (> 3 logs) S. muta …
The isolation and characterization of 2-carboxyethyl adducts following in vitro reaction of acrylic acid with calf thymus DNA and bioassay of acrylic acid in female Hsd:(ICR)Br mice.
Segal A, Fedyk J, Melchionne S, Seidman I. Segal A, et al. Chem Biol Interact. 1987 Feb;61(2):189-97. doi: 10.1016/0009-2797(87)90039-1. Chem Biol Interact. 1987. PMID: 3829142 Free article.
Reaction of acrylic acid (AA) at pH 7.0 and 37 degrees C for 40 days with 2'-deoxyadenosine (dAdo), 2'-deoxycytidine (dCyd), 2'-deoxyguanosine (dGuo) and thymidine (dThd) resulted in the formation of 2-carboxyethyl (CE) adducts via Michael addition. The alkylated 2'-deoxyn …
Reaction of acrylic acid (AA) at pH 7.0 and 37 degrees C for 40 days with 2'-deoxyadenosine (dAdo), 2'-deoxycytidine (dCyd), 2'-deoxyguanosi …
In vitro alkylation of calf thymus DNA by acrylonitrile. Isolation of cyanoethyl-adducts of guanine and thymine and carboxyethyl-adducts of adenine and cytosine.
Solomon JJ, Cote IL, Wortman M, Decker K, Segal A. Solomon JJ, et al. Chem Biol Interact. 1984 Sep 15;51(2):167-90. doi: 10.1016/0009-2797(84)90028-0. Chem Biol Interact. 1984. PMID: 6331902
Adducts were not detected after 4 h. The adducts isolated were 1-(2-carboxyethyl)-dAdo (1-CE-dAdo), N6-CE-dAdo, 3-CE-dCyd, 7-(2-cyanoethyl)-Gua (7-CNE-Gua), 7,9-bis-CNE-Gua, imidazole ring-opened 7,9-bis-CNE-Gua, 1-CNE-dIno, 1-C …
Adducts were not detected after 4 h. The adducts isolated were 1-(2-carboxyethyl)-dAdo (1-CE-dAdo), N6-CE-dAdo, 3-CE-dC …
Uncovering the Signaling Pathway behind Extracellular Guanine-Induced Activation of NO System: New Perspectives in Memory-Related Disorders.
Zuccarini M, Giuliani P, Frinchi M, Mudò G, Serio RM, Belluardo N, Buccella S, Carluccio M, Condorelli DF, Caciagli F, Ciccarelli R, Di Iorio P. Zuccarini M, et al. Front Pharmacol. 2018 Feb 21;9:110. doi: 10.3389/fphar.2018.00110. eCollection 2018. Front Pharmacol. 2018. PMID: 29515443 Free PMC article.
Noteworthy, GUO and GUA, seem to play opposite roles in the modulation of cognitive functions, such as learning and memory. ...These molecular mechanisms activated by GUA may be useful to support our previous observation showing that GUA improves learning and …
Noteworthy, GUO and GUA, seem to play opposite roles in the modulation of cognitive functions, such as learning and memory. ...These …
Capillary electrophoretic determination of DNA damage markers: content of 8-hydroxy-2'-deoxyguanosine and 8-nitroguanine in urine.
Li MJ, Zhang JB, Li WL, Chu QC, Ye JN. Li MJ, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Dec 15;879(32):3818-22. doi: 10.1016/j.jchromb.2011.10.026. Epub 2011 Oct 29. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 22098717
A sensitive and low-cost analytical method has been developed to determine 8-hydroxy-2'-deoxyguanosine (8-OHdG) and 8-nitroguanine (8-NO(2)Gua) based on capillary electrophoresis with amperometric detection (CE-AD) after solid phase extraction (SPE). ...The average …
A sensitive and low-cost analytical method has been developed to determine 8-hydroxy-2'-deoxyguanosine (8-OHdG) and 8-nitroguanine (8-NO(2) …
Direct alkylation of 2'-deoxynucleosides and DNA following in vitro reaction with acrylamide.
Solomon JJ, Fedyk J, Mukai F, Segal A. Solomon JJ, et al. Cancer Res. 1985 Aug;45(8):3465-70. Cancer Res. 1985. PMID: 4016731
The alkylated 2'-deoxynucleoside adducts isolated (% yield after 40 days) were 1-(2-carboxyethyl)-dAdo (1-CE-dAdo) (8%), N6-CE-dAdo (21%) (via Dimroth rearrangement of 1-CE-dAdo), 1-CE-dGuo (4%), 7-(2-formamidoethyl)-Gua (7-FAE-Gua) (6%), …
The alkylated 2'-deoxynucleoside adducts isolated (% yield after 40 days) were 1-(2-carboxyethyl)-dAdo (1-CE-dAdo) (8%), N6-CE …
Direct alkylation of calf thymus DNA by acrylonitrile. Isolation of cyanoethyl adducts of guanine and thymine and carboxyethyl adducts of adenine and cytosine.
Solomon JJ, Segal A. Solomon JJ, et al. Environ Health Perspect. 1985 Oct;62:227-30. doi: 10.1289/ehp.8562227. Environ Health Perspect. 1985. PMID: 4085427 Free PMC article.
Reaction of the rodent carcinogen acrylonitrile (AN) at pH 7.0 for 10 and/or 40 days with 2'-deoxyadenosine (dAdo), 2'-deoxycytidine (dCyd), 2'-deoxyguanosine (dGuo), 2'-deoxyinosine (dIno), and thymidine (dThd) resulted in the formation of cyanoethyl and carboxyethyl adducts. Th …
Reaction of the rodent carcinogen acrylonitrile (AN) at pH 7.0 for 10 and/or 40 days with 2'-deoxyadenosine (dAdo), 2'-deoxycytidine (dCyd), …
2-Deoxy-D-glucose uptake by chick embryo cells: a biochemical indicator of genetic susceptibility to RNA tumour viruses.
Pani PK, Ross LJ. Pani PK, et al. J Gen Virol. 1976 Jul;32(1):97-107. doi: 10.1099/0022-1317-32-1-97. J Gen Virol. 1976. PMID: 182917
We concluded therefore that the statistic of glucose uptake assay (GUA) measured at 72 p.i. is less sensitive than that of the focus count assay (FCA) measured after 10 days as a measure of assessing cellular transformation by RSV. Nevertheless, when the cultures were infe …
We concluded therefore that the statistic of glucose uptake assay (GUA) measured at 72 p.i. is less sensitive than that of the focus …
Chromosomal mapping of tRNA genes from Dictyostelium discoideum.
Dingermann T, Amon E, Williams KL, Welker DL. Dingermann T, et al. Mol Gen Genet. 1987 Apr;207(1):176-87. doi: 10.1007/BF00331507. Mol Gen Genet. 1987. PMID: 3474495
These size differences were used to study the organisation of two tRNA gene families which encode a tRNA Val(GUU) and a tRNA Val(GUA) gene. The method used involved a combination of classical D. discoideum parasexual genetics and molecular genetics. ...Information of nine …
These size differences were used to study the organisation of two tRNA gene families which encode a tRNA Val(GUU) and a tRNA Val(GUA) …