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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1824 1
1898 1
1900 1
1909 1
1910 1
1911 1
1913 1
1915 1
1917 1
1923 1
1925 1
1926 3
1927 3
1930 1
1931 1
1932 2
1933 1
1936 1
1937 2
1938 2
1939 2
1940 3
1942 1
1943 2
1944 1
1945 3
1946 2
1947 6
1948 5
1949 6
1950 6
1951 8
1952 13
1953 8
1954 10
1955 9
1956 15
1957 10
1958 12
1959 11
1960 20
1961 20
1962 28
1963 30
1964 47
1965 49
1966 63
1967 88
1968 94
1969 89
1970 129
1971 122
1972 121
1973 127
1974 140
1975 650
1976 641
1977 605
1978 641
1979 714
1980 759
1981 905
1982 958
1983 1164
1984 1338
1985 1338
1986 1423
1987 1402
1988 1497
1989 1598
1990 1667
1991 1655
1992 1703
1993 1869
1994 1941
1995 1870
1996 1991
1997 1972
1998 2039
1999 2099
2000 2135
2001 2114
2002 2200
2003 2278
2004 2641
2005 2821
2006 3036
2007 3223
2008 3523
2009 3839
2010 3983
2011 4423
2012 4869
2013 5104
2014 5361
2015 5700
2016 5764
2017 5948
2018 6258
2019 6466
2020 6797
2021 7297
2022 7245
2023 6911
2024 2598

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134,127 results

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Page 1
Brain aging mechanisms with mechanical manifestations.
Blinkouskaya Y, Caçoilo A, Gollamudi T, Jalalian S, Weickenmeier J. Blinkouskaya Y, et al. Mech Ageing Dev. 2021 Dec;200:111575. doi: 10.1016/j.mad.2021.111575. Epub 2021 Oct 1. Mech Ageing Dev. 2021. PMID: 34600936 Free PMC article. Review.
Pathophysiologically, brain aging is associated with neuron cell shrinking, dendritic degeneration, demyelination, small vessel disease, metabolic slowing, microglial activation, and the formation of white matter lesions. In recent years, the mechanics community has …
Pathophysiologically, brain aging is associated with neuron cell shrinking, dendritic degeneration, demyelination, small vesse …
Beyond the binary: Rethinking sex and the brain.
Joel D. Joel D. Neurosci Biobehav Rev. 2021 Mar;122:165-175. doi: 10.1016/j.neubiorev.2020.11.018. Epub 2021 Jan 10. Neurosci Biobehav Rev. 2021. PMID: 33440198 Free article. Review.
Recent formulations of the binary framework range from arguing that the typical male brain is different from the typical female brain to claiming that brains are typically male or female because brain structure can be used to predict the sex category ( …
Recent formulations of the binary framework range from arguing that the typical male brain is different from the typical female br …
Complex brain networks: graph theoretical analysis of structural and functional systems.
Bullmore E, Sporns O. Bullmore E, et al. Nat Rev Neurosci. 2009 Mar;10(3):186-98. doi: 10.1038/nrn2575. Epub 2009 Feb 4. Nat Rev Neurosci. 2009. PMID: 19190637 Review.
Recent developments in the quantitative analysis of complex networks, based largely on graph theory, have been rapidly translated to studies of brain network organization. The brain's structural and functional systems have features of complex networks--such a …
Recent developments in the quantitative analysis of complex networks, based largely on graph theory, have been rapidly translated to studies …
Small cells with big implications: Microglia and sex differences in brain development, plasticity and behavioral health.
Nelson LH, Saulsbery AI, Lenz KM. Nelson LH, et al. Prog Neurobiol. 2019 May;176:103-119. doi: 10.1016/j.pneurobio.2018.09.002. Epub 2018 Sep 5. Prog Neurobiol. 2019. PMID: 30193820 Free PMC article. Review.
The brain's resident immune cells, called microglia, actively contribute to brain development. Recent research has shown that microglia are sexually dimorphic, especially during early life, and may participate in sex-specific organization of the brain …
The brain's resident immune cells, called microglia, actively contribute to brain development. Recent research has show …
Morphology of Microglia Across Contexts of Health and Disease.
Savage JC, Carrier M, Tremblay MÈ. Savage JC, et al. Methods Mol Biol. 2019;2034:13-26. doi: 10.1007/978-1-4939-9658-2_2. Methods Mol Biol. 2019. PMID: 31392674 Review.
Microglia, the brain's resident macrophages, are incredibly plastic and dynamic cells. In this chapter, we aim to describe and classify the many morphological changes they can display in normal development, aging, and disease. Although microglia in healthy adult …
Microglia, the brain's resident macrophages, are incredibly plastic and dynamic cells. In this chapter, we aim to describe and …
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
Jia W, Tian H, Jiang J, Zhou L, Li L, Luo M, Ding N, Nice EC, Huang C, Zhang H. Jia W, et al. Small. 2023 Jan;19(2):e2205354. doi: 10.1002/smll.202205354. Epub 2022 Nov 18. Small. 2023. PMID: 36399643
However, poor site-specific delivery and bioavailability significantly restrict the efficient permeability of regorafenib to brain lesions and compromise its treatment efficacy. Therefore, human H-ferritin (HFn), regorafenib, and Cu(2+) are rationally designed as a brai …
However, poor site-specific delivery and bioavailability significantly restrict the efficient permeability of regorafenib to brain le …
The big and the small: challenges of imaging the brain's circuits.
Lichtman JW, Denk W. Lichtman JW, et al. Science. 2011 Nov 4;334(6056):618-23. doi: 10.1126/science.1209168. Science. 2011. PMID: 22053041 Review.
We explore why bridging the structure-function divide is uniquely difficult in the brain. These difficulties also explain the thrust behind the enormous amount of innovation centered on microscopy in neuroscience. ...
We explore why bridging the structure-function divide is uniquely difficult in the brain. These difficulties also explain the thrust …
Small brains for big science.
Makarova AA, Polilov AA, Chklovskii DB. Makarova AA, et al. Curr Opin Neurobiol. 2021 Dec;71:77-83. doi: 10.1016/j.conb.2021.09.007. Epub 2021 Oct 14. Curr Opin Neurobiol. 2021. PMID: 34656052 Free article. Review.
The brains of macaque, mouse, zebrafish, fruit fly, nematode, and others have yielded many secrets that advanced our understanding of the human brain. ...Finally, the brains of miniature insects offer insights into the evolution of brain design....
The brains of macaque, mouse, zebrafish, fruit fly, nematode, and others have yielded many secrets that advanced our understanding of …
Microfluidic Brain-on-a-Chip: From Key Technology to System Integration and Application.
Wang Z, Zhang Y, Li Z, Wang H, Li N, Deng Y. Wang Z, et al. Small. 2023 Dec;19(52):e2304427. doi: 10.1002/smll.202304427. Epub 2023 Aug 31. Small. 2023. PMID: 37653590 Review.
As an ideal in vitro model, brain-on-chip (BoC) is an important tool to comprehensively elucidate brain characteristics. However, the in vitro model for the definition scope of BoC has not been universally recognized. In this review, BoC is divided into brain …
As an ideal in vitro model, brain-on-chip (BoC) is an important tool to comprehensively elucidate brain characteristics. Howev …
Drug Repurposing-Based Brain-Targeting Self-Assembly Nanoplatform Using Enhanced Ferroptosis against Glioblastoma.
Liang J, Li L, Tian H, Wang Z, Liu G, Duan X, Guo M, Liu J, Zhang W, Nice EC, Huang C, He W, Zhang H, Li Q. Liang J, et al. Small. 2023 Nov;19(46):e2303073. doi: 10.1002/smll.202303073. Epub 2023 Jul 17. Small. 2023. PMID: 37460404
Glioblastoma (GBM), the most aggressive and lethal form of malignant brain tumor, is a therapeutic challenge due to the drug filtration capabilities of the blood-brain barrier (BBB). ...
Glioblastoma (GBM), the most aggressive and lethal form of malignant brain tumor, is a therapeutic challenge due to the drug filtrati …
134,127 results
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