Evidence for label-retaining tumour-initiating cells in human glioblastoma.
Brain. 2011.
PMID: 21515906
Free PMC article.
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148 results
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Microglial large extracellular vesicles propagate early synaptic dysfunction in Alzheimer's disease.
Brain. 2022.
PMID: 35254410
Free PMC article.
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Page 1
P2X7 Receptor and Extracellular Vesicle Release.
Int J Mol Sci. 2023 Jun 6;24(12):9805. doi: 10.3390/ijms24129805.
Int J Mol Sci. 2023.
PMID: 37372953
Free PMC article.
Review.
Extensive evidence indicates that the activation of the P2X(7) receptor (P2X(7)R), an ATP-gated ion channel highly expressed in immune and brain cells, is strictly associated with the release of extracellular vesicles. ...
Extensive evidence indicates that the activation of the P2X(7) receptor (P2X(7)R), an ATP-gated ion channel highly expressed in immune and …
COVID-19 and the Brain: The Neuropathological Italian Experience on 33 Adult Autopsies.
Biomolecules. 2022 Apr 25;12(5):629. doi: 10.3390/biom12050629.
Biomolecules. 2022.
PMID: 35625558
Free PMC article.
However, the neuropathogenesis remains unclear and it is not possible to define a specific damage pattern due to brain virus infection. In the present study, 33 cases of brain autopsies performed during the first (February-April 2020) and the second/third (November …
However, the neuropathogenesis remains unclear and it is not possible to define a specific damage pattern due to brain virus infectio …
Microglial large extracellular vesicles propagate early synaptic dysfunction in Alzheimer's disease.
Brain. 2022 Aug 27;145(8):2849-2868. doi: 10.1093/brain/awac083.
Brain. 2022.
PMID: 35254410
Free PMC article.
Synaptic dysfunction is an early mechanism in Alzheimer's disease that involves progressively larger areas of the brain over time. However, how it starts and propagates is unknown. ...Our data indicate the involvement of large microglial extracellular vesicles in the rise …
Synaptic dysfunction is an early mechanism in Alzheimer's disease that involves progressively larger areas of the brain over time. Ho …
Fetal Brain Damage in Human Fetuses with Congenital Cytomegalovirus Infection: Histological Features and Viral Tropism.
Cell Mol Neurobiol. 2023 Apr;43(3):1385-1399. doi: 10.1007/s10571-022-01258-9. Epub 2022 Aug 7.
Cell Mol Neurobiol. 2023.
PMID: 35933637
Free PMC article.
Human cytomegalovirus (HCMV) causes congenital neurological lifelong disabilities. To date, the neuropathogenesis of brain injury related to congenital HCMV (cCMV) infection is poorly understood. ...This could lead to known structural and functional brain defects fr …
Human cytomegalovirus (HCMV) causes congenital neurological lifelong disabilities. To date, the neuropathogenesis of brain injury rel …
[Long COVID: nosographic aspects and clinical epidemiology].
G Ital Cardiol (Rome). 2022 Sep;23(9):651-662. doi: 10.1714/3860.38447.
G Ital Cardiol (Rome). 2022.
PMID: 36039714
Review.
Italian.
Patients can manifest with a very heterogeneous multitude of symptoms, including fatigue, post-exertional malaise, dyspnea, cognitive impairment, sleep disturbances, anxiety and depression, muscle pain, brain fog, anosmia/dysgeusia, headache, and limitation of functional c …
Patients can manifest with a very heterogeneous multitude of symptoms, including fatigue, post-exertional malaise, dyspnea, cognitive impair …
Linoleic acid: Is this the key that unlocks the quantum brain? Insights linking broken symmetries in molecular biology, mood disorders and personalistic emergentism.
BMC Neurosci. 2017 Apr 19;18(1):38. doi: 10.1186/s12868-017-0356-1.
BMC Neurosci. 2017.
PMID: 28420346
Free PMC article.
Review.
In this paper we present a mechanistic model that integrates subneuronal structures, namely ion channels, membrane fatty acids, lipid rafts, G proteins and the cytoskeleton in a dynamic system that is finely tuned in a healthy brain. We also argue that subtle changes in th …
In this paper we present a mechanistic model that integrates subneuronal structures, namely ion channels, membrane fatty acids, lipid rafts, …
Emerging Roles of Extracellular Vesicles in Alzheimer's Disease: Focus on Synaptic Dysfunction and Vesicle-Neuron Interaction.
Cells. 2022 Dec 23;12(1):63. doi: 10.3390/cells12010063.
Cells. 2022.
PMID: 36611856
Free PMC article.
Review.
While the reciprocal involvement of amyloid beta (Abeta) and tau peptides in these processes is under intense investigation, the crucial role of extracellular vesicles (EVs) released by different brain cells as vehicles for these molecules and as mediators of early synapti …
While the reciprocal involvement of amyloid beta (Abeta) and tau peptides in these processes is under intense investigation, the crucial rol …
Non-Gaussian diffusion imaging: a brief practical review.
Magn Reson Imaging. 2011 Dec;29(10):1410-6. doi: 10.1016/j.mri.2011.04.006. Epub 2011 May 20.
Magn Reson Imaging. 2011.
PMID: 21601404
Review.
The departure from purely mono-exponential decay of the signal, as observed from brain tissue following a diffusion-sensitized sequence, has prompted the search for alternative models to characterize these unconventional water diffusion dynamics. ...However, since the ulti …
The departure from purely mono-exponential decay of the signal, as observed from brain tissue following a diffusion-sensitized sequen …
Recent Advances and Future Directions in Syncope Management: A Comprehensive Narrative Review.
J Clin Med. 2024 Jan 26;13(3):727. doi: 10.3390/jcm13030727.
J Clin Med. 2024.
PMID: 38337421
Free PMC article.
Review.
This symptom carries significance, as its potential underlying causes may involve the heart, blood pressure, or brain, leading to a spectrum of consequences, from sudden death to compromised quality of life. ...
This symptom carries significance, as its potential underlying causes may involve the heart, blood pressure, or brain, leading to a s …
The multiple faces of extracellular vesicles released by microglia: Where are we 10 years after?
Front Cell Neurosci. 2022 Sep 13;16:984690. doi: 10.3389/fncel.2022.984690. eCollection 2022.
Front Cell Neurosci. 2022.
PMID: 36176630
Free PMC article.
Review.
As resident component of the innate immunity in the central nervous system (CNS), microglia are key players in pathology. However, they also exert fundamental roles in brain development and homeostasis maintenance. They are extremely sensitive and plastic, as they assiduou …
As resident component of the innate immunity in the central nervous system (CNS), microglia are key players in pathology. However, they also …
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