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Page 1
Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016.
Srivastava AK, Wang Y, Huang R, Skinner C, Thompson T, Pollard L, Wood T, Luo F, Stevenson R, Polimanti R, Gelernter J, Lin X, Lim IY, Wu Y, Teh AL, Chen L, Aris IM, Soh SE, Tint MT, MacIsaac JL, Yap F, Kwek K, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Holbrook JD, Lee YS, Gluckman PD, Karnani N; GUSTO study group; Kapoor A, Lee D, Chakravarti A, Maercker C, Graf F, Boutros M, Stamoulis G, Santoni F, Makrythanasis P, Letourneau A, Guipponi M, Panousis N, Garieri M, Ribaux P, Falconnet E, Borel C, Antonarakis SE, Kumar S, Curran J, Blangero J, Chatterjee S, Kapoor A, Akiyama J, Auer D, Berrios C, Pennacchio L, Chakravarti A, Donti TR, Cappuccio G, Miller M, Atwal P, Kennedy A, Cardon A, Bacino C, Emrick L, Hertecant J, Baumer F, Porter B, Bainbridge M, Bonnen P, Graham B, Sutton R, Sun Q, Elsea S, Hu Z, Wang P, Zhu Y, Zhao J, Xiong M, Bennett DA, Hidalgo-Miranda A, Romero-Cordoba S, Rodriguez-Cuevas S, Rebollar-Vega R, Tagliabue E, Iorio M, D’Ippolito E, Baroni S, Kaczkowski B, Tanaka Y, Kawaji H, Sandelin A, Andersson R, Itoh M, Lassmann T; The FANTOM5 Consortium; Hayashizaki Y, Carninci P, Forrest ARR, Semple CA, Rosenthal EA, Shirts B, Amendola L, Gallego C, Horike-Pyne… See abstract for full author list ➔ Srivastava AK, et al. Hum Genomics. 2016 May 26;10 Suppl 1(Suppl 1):12. doi: 10.1186/s40246-016-0063-5. Hum Genomics. 2016. PMID: 27294413 Free PMC article.
Gibbs O38 Melanoma reprogramming state correlates with response to CTLA-4 blockade in metastatic melanoma T. Karpinets, T. Calderone, K. Wani, X. Yu, C. Creasy, C. Haymaker, M. ...Stolzenberg-Solomon, S. Weinstein, D. Albanes, C.-S. Liu, W.-L. Cheng, T.-T …
Gibbs O38 Melanoma reprogramming state correlates with response to CTLA-4 blockade in metastatic melanoma T. Karpinets, T. Cal …
Analogues of the frog skin peptide alyteserin-2a with enhanced antimicrobial activities against Gram-negative bacteria.
Conlon JM, Mechkarska M, Arafat K, Attoub S, Sonnevend A. Conlon JM, et al. J Pept Sci. 2012 Apr;18(4):270-5. doi: 10.1002/psc.2397. Epub 2012 Mar 5. J Pept Sci. 2012. PMID: 22392897
However, the peptide containing D-lysine at positions 7 and 11 showed high potency against a range of Gram-negative bacteria, including multidrug-resistant strains of Acinetobacter baumannii and Stenotrophomonas maltophilia (minimum inhibitory concentration = 8 M) but appreciably …
However, the peptide containing D-lysine at positions 7 and 11 showed high potency against a range of Gram-negative bacteria, including mult …
Frondoside a suppressive effects on lung cancer survival, tumor growth, angiogenesis, invasion, and metastasis.
Attoub S, Arafat K, Gélaude A, Al Sultan MA, Bracke M, Collin P, Takahashi T, Adrian TE, De Wever O. Attoub S, et al. PLoS One. 2013;8(1):e53087. doi: 10.1371/journal.pone.0053087. Epub 2013 Jan 8. PLoS One. 2013. PMID: 23308143 Free PMC article. Retracted.
Frondoside A (0.01 and 1 mg/kg/day i.p. for 25 days) significantly decreased the growth, the angiogenesis and lymph node metastasis of LNM35 tumor xenografts in athymic mice, without obvious toxic side-effects. Frondoside A (0.1-0.5 M) also significantly prevented basal an …
Frondoside A (0.01 and 1 mg/kg/day i.p. for 25 days) significantly decreased the growth, the angiogenesis and lymph node metastasis of LNM35 …
Creating a tumor-resistant microenvironment: cell-mediated delivery of TNFα completely prevents breast cancer tumor formation in vivo.
Al-Zoubi M, Salem AF, Martinez-Outschoorn UE, Whitaker-Menezes D, Lamb R, Hulit J, Howell A, Gandara R, Sartini M, Arafat H, Bevilacqua G, Sotgia F, Lisanti MP. Al-Zoubi M, et al. Cell Cycle. 2013 Feb 1;12(3):480-90. doi: 10.4161/cc.23370. Epub 2012 Feb 1. Cell Cycle. 2013. PMID: 23292149 Free PMC article.
Remarkably, TNFalpha-expressing breast cancer cells were viable, without any significant increases in their basal apoptotic rate. However, after 4 weeks post-implantation, TNFalpha-expressing breast cancer cells failed to form any tumors in xenografted mice (0 tumors/10 in …
Remarkably, TNFalpha-expressing breast cancer cells were viable, without any significant increases in their basal apoptotic rate. How …
Combination of RAD001 (everolimus) and docetaxel reduces prostate and breast cancer cell VEGF production and tumour vascularisation independently of sphingosine-kinase-1.
Alshaker H, Wang Q, Böhler T, Mills R, Winkler M, Arafat T, Kawano Y, Pchejetski D. Alshaker H, et al. Sci Rep. 2017 Jun 14;7(1):3493. doi: 10.1038/s41598-017-03728-3. Sci Rep. 2017. PMID: 28615679 Free PMC article.
In these cell lines, SK1 overexpression slightly increased the basal levels of VEGF, but did not block the inhibitory effect of RAD001 on VEGF. ...
In these cell lines, SK1 overexpression slightly increased the basal levels of VEGF, but did not block the inhibitory effect of RAD00 …
Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain.
Nasser A, Bjerrum OJ, Heegaard AM, Møller AT, Larsen M, Dalbøge LS, Dupont E, Jensen TS, Møller LB. Nasser A, et al. Mol Pain. 2013 Feb 19;9:5. doi: 10.1186/1744-8069-9-5. Mol Pain. 2013. PMID: 23421753 Free PMC article.
Contrary, loss of function mutations in the GCH1 gene results in decreased basal GCH1 expression, and is associated with DOPA-responsive dystonia (DRD). ...Together, the present data suggest that BH4 is not important for basal heat and mechanical pain, but they supp …
Contrary, loss of function mutations in the GCH1 gene results in decreased basal GCH1 expression, and is associated with DOPA-respons …
Kinomic profiling of electromagnetic navigational bronchoscopy specimens: a new approach for personalized medicine.
Anderson JC, Minnich DJ, Dobelbower MC, Denton AJ, Dussaq AM, Gilbert AN, Rohrbach TD, Arafat W, Welaya K, Bonner JA, Willey CD. Anderson JC, et al. PLoS One. 2014 Dec 30;9(12):e116388. doi: 10.1371/journal.pone.0116388. eCollection 2014. PLoS One. 2014. PMID: 25549342 Free PMC article.
METHODS: Eight patients with lung lesions of varying location and size were biopsied using the novel electromagnetic navigational bronchoscopy (ENB) technique. Basal kinase activity (kinomic) profiles and ex vivo interrogation of samples in combination with tyrosine kinase …
METHODS: Eight patients with lung lesions of varying location and size were biopsied using the novel electromagnetic navigational bronchosco …
Influence of the hepatic eukaryotic initiation factor 2alpha (eIF2alpha) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolism.
Birkenfeld AL, Lee HY, Majumdar S, Jurczak MJ, Camporez JP, Jornayvaz FR, Frederick DW, Guigni B, Kahn M, Zhang D, Weismann D, Arafat AM, Pfeiffer AF, Lieske S, Oyadomari S, Ron D, Samuel VT, Shulman GI. Birkenfeld AL, et al. J Biol Chem. 2011 Oct 21;286(42):36163-70. doi: 10.1074/jbc.M111.228817. Epub 2011 Aug 5. J Biol Chem. 2011. PMID: 21832042 Free PMC article.
Inhibition of the eIF2alpha-P signaling in liver led to a decrease in hepatic glucose production in the basal and clamped state, which could be attributed to reduced gluconeogenic gene expression, resulting in reduced basal plasma glucose concentrations. ...
Inhibition of the eIF2alpha-P signaling in liver led to a decrease in hepatic glucose production in the basal and clamped state, whic …
Osteopontin gene expression and immunolocalization in the rabbit urinary tract.
Arafat HA, Wein AJ, Chacko S. Arafat HA, et al. J Urol. 2002 Feb;167(2 Pt 1):746-52. doi: 10.1016/S0022-5347(01)69138-9. J Urol. 2002. PMID: 11792965
Immunohistochemical staining revealed osteopontin expression in all layers of the transitional epithelium of the bladder, co-localizing with alphavbeta3 integrin mainly in the superficial layers and with CD44 mainly in the basal layers. Osteopontin was detected within the …
Immunohistochemical staining revealed osteopontin expression in all layers of the transitional epithelium of the bladder, co-localizing with …
Study of the concentration of the herbicide (2,4-dichlorophenoxy)-acetic acid in coca leaves and paste obtained from plants treated with this herbicide.
Elsohly MA, Arafat ES, Jones AB, Vincent PG, Engelke BF, Hilton JL, Gentner WA. Elsohly MA, et al. Bull Narc. 1984 Apr-Jun;36(2):65-77. Bull Narc. 1984. PMID: 6569823
Since coca leaves are chewed by the natives of coca producing areas, and, since coca paste and cocaine are widely abused, a study was undertaken to determine whether 2,4-D is translocated into the leaves and transferred to coca paste when coca plants are treated with this herbici …
Since coca leaves are chewed by the natives of coca producing areas, and, since coca paste and cocaine are widely abused, a study was undert …