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Effects of Cyanobacterial Harmful Algal Bloom Toxin Microcystin-LR on Gonadotropin-Dependent Ovarian Follicle Maturation and Ovulation in Mice.
Wang Y, Pattarawat P, Zhang J, Kim E, Zhang D, Fang M, Jannaman EA, Yuan Y, Chatterjee S, Kim JJ, Scott GI, Zhang Q, Xiao S. Wang Y, et al. Environ Health Perspect. 2023 Jun;131(6):67010. doi: 10.1289/EHP12034. Epub 2023 Jun 21. Environ Health Perspect. 2023. PMID: 37342990 Free PMC article.
METHODS: Mouse models with either chronic daily oral or acute intraperitoneal exposure, an engineered three-dimensional ovarian follicle culture system, and human primary ovarian granulosa cells were tested with MC-LR of various dose levels. Single-follicle RNA sequencing, …
METHODS: Mouse models with either chronic daily oral or acute intraperitoneal exposure, an engineered three-dimensional ovarian follicle cul …
Twenty New Records of Bees (Hymenoptera, Apoidea) for Sardinia (Italy).
Nobile V, Catania R, Niolu P, Pusceddu M, Satta A, Floris I, Flaminio S, Bella S, Quaranta M. Nobile V, et al. Insects. 2021 Jul 10;12(7):627. doi: 10.3390/insects12070627. Insects. 2021. PMID: 34357287 Free PMC article.
Here, for the first time, the following 20 taxa are reported: Colletes cunicularius (Linnaeus, 1761), and C. eous Morice, 1904 (Colletidae); Andrena humilis Imhoff, 1832, A. granulosa Perez, 1902, A. cineraria (Linnaeus, 1758), A. pallitarsis Perez, 1903, A. rugulosa Stock …
Here, for the first time, the following 20 taxa are reported: Colletes cunicularius (Linnaeus, 1761), and C. eous Morice, 1904 (Colletidae); …
Expression of mRNA and protein of IL-18 and its receptor in human follicular granulosa cells.
Salmassi A, Fattahi A, Nouri M, Hedderich J, Schmutzler AG. Salmassi A, et al. J Endocrinol Invest. 2017 Apr;40(4):447-454. doi: 10.1007/s40618-016-0590-x. Epub 2016 Dec 2. J Endocrinol Invest. 2017. PMID: 27914037
PURPOSE: There is no information available about the IL-18 receptor in ovarian follicles, so the present study attempts to demonstrate the expression of IL-18 and its receptor in human granulosa cells (GCs). METHODS: To evaluate the concentration of IL-18 in serum and foll …
PURPOSE: There is no information available about the IL-18 receptor in ovarian follicles, so the present study attempts to demonstrate the e …
FSH/LH-Dependent Upregulation of Ahr in Murine Granulosa Cells Is Controlled by PKA Signaling and Involves Epigenetic Regulation.
Matvere A, Teino I, Varik I, Kuuse S, Tiido T, Kristjuhan A, Maimets T. Matvere A, et al. Int J Mol Sci. 2019 Jun 23;20(12):3068. doi: 10.3390/ijms20123068. Int J Mol Sci. 2019. PMID: 31234584 Free PMC article.
Recent studies have established its importance in many physiological processes including female reproduction, although there is limited data about the precise mechanisms how Ahr itself is regulated during ovarian follicle maturation. This study describes the expression of Ahr in …
Recent studies have established its importance in many physiological processes including female reproduction, although there is limited data …
Intrafollicular injection of nanomolecules for advancing knowledge on folliculogenesis in livestock.
Feugang JM, Ishak GM, Eggert MW, Arnold RD, Rivers OS, Willard ST, Ryan PL, Gastal EL. Feugang JM, et al. Theriogenology. 2022 Oct 15;192:132-140. doi: 10.1016/j.theriogenology.2022.08.032. Epub 2022 Aug 27. Theriogenology. 2022. PMID: 36099803
Ovarian follicles of living mares were injected in vivo with fluorescently labeled liposomes. Samples of the follicular wall (mural granulosa, theca interna, and theca externa), granulosa cells, and follicular fluid were harvested 24 h post-injection through the fol …
Ovarian follicles of living mares were injected in vivo with fluorescently labeled liposomes. Samples of the follicular wall (mural granu …
Necroptosis in primate luteolysis: a role for ceramide.
Bagnjuk K, Stöckl JB, Fröhlich T, Arnold GJ, Behr R, Berg U, Berg D, Kunz L, Bishop C, Xu J, Mayerhofer A. Bagnjuk K, et al. Cell Death Discov. 2019 Feb 11;5:67. doi: 10.1038/s41420-019-0149-7. eCollection 2019. Cell Death Discov. 2019. PMID: 30774995 Free PMC article.
Cell death, including necroptosis, was previously observed in cultures of human luteal granulosa cells (GCs), an apt model for the study of the human CL. ...
Cell death, including necroptosis, was previously observed in cultures of human luteal granulosa cells (GCs), an apt model for the st …
Doxorubicin obliterates mouse ovarian reserve through both primordial follicle atresia and overactivation.
Wang Y, Liu M, Johnson SB, Yuan G, Arriba AK, Zubizarreta ME, Chatterjee S, Nagarkatti M, Nagarkatti P, Xiao S. Wang Y, et al. Toxicol Appl Pharmacol. 2019 Oct 15;381:114714. doi: 10.1016/j.taap.2019.114714. Epub 2019 Aug 19. Toxicol Appl Pharmacol. 2019. PMID: 31437492 Free PMC article.
Twenty-one-day-old CD-1 female mice were intraperitoneally injected with PBS or clinically relevant dose of DOX at 10 mg/kg once. Results indicated that DOX primarily damaged granulosa cells in growing follicles and oocytes in primordial follicles and DOX-induced growing f …
Twenty-one-day-old CD-1 female mice were intraperitoneally injected with PBS or clinically relevant dose of DOX at 10 mg/kg once. Results in …
Readthrough acetylcholinesterase (AChE-R) and regulated necrosis: pharmacological targets for the regulation of ovarian functions?
Blohberger J, Kunz L, Einwang D, Berg U, Berg D, Ojeda SR, Dissen GA, Fröhlich T, Arnold GJ, Soreq H, Lara H, Mayerhofer A. Blohberger J, et al. Cell Death Dis. 2015 Mar 12;6(3):e1685. doi: 10.1038/cddis.2015.51. Cell Death Dis. 2015. PMID: 25766324 Free PMC article.
We identified enzymatically active acetylcholinesterase (AChE) in human ovarian follicular fluid as a product of human granulosa cells. AChE breaks down ACh and thereby attenuates its trophic functions. ...AChE-R was found in follicular fluid, granulosa and theca ce …
We identified enzymatically active acetylcholinesterase (AChE) in human ovarian follicular fluid as a product of human granulosa cell …
A Tiered Female Ovarian Toxicity Screening Identifies Toxic Effects of Checkpoint Kinase 1 Inhibitors on Murine Growing Follicles.
Xu J, Wang Y, Kauffman AE, Zhang Y, Li Y, Zhu J, Maratea K, Fabre K, Zhang Q, Woodruff TK, Xiao S. Xu J, et al. Toxicol Sci. 2020 Oct 1;177(2):405-419. doi: 10.1093/toxsci/kfaa118. Toxicol Sci. 2020. PMID: 32697846 Free PMC article.
However, AZ-H, a preclinical compound targeting the checkpoint kinase 1 inhibitor to potentiate the anticancer effects of DNA-damaging agents, significantly promoted granulosa cell apoptosis and the entire growing follicle atresia at clinically relevant concentrations of 1 …
However, AZ-H, a preclinical compound targeting the checkpoint kinase 1 inhibitor to potentiate the anticancer effects of DNA-damaging agent …
Expression of endothelial nitric oxide synthase in the ovine ovary throughout the estrous cycle.
Grazul-Bilska AT, Navanukraw C, Johnson ML, Arnold DA, Reynolds LP, Redmer DA. Grazul-Bilska AT, et al. Reproduction. 2006 Oct;132(4):579-87. doi: 10.1530/REP-06-0009. Reproduction. 2006. PMID: 17008469
During the immediate postovulatory period, eNOS protein expression was detected in thecal-derived cells that appeared to be invading the granulosa layer. Expression of eNOS mRNA tended to increase in granulosa cells at 12 and 24 h, and in theca cells 48 h after hCG …
During the immediate postovulatory period, eNOS protein expression was detected in thecal-derived cells that appeared to be invading the …
12 results