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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1972 1
1975 1
1978 1
1980 1
1981 2
1984 4
1985 4
1986 1
1987 1
1988 2
1989 3
1990 4
1991 2
1992 4
1993 6
1994 4
1995 5
1996 3
1997 9
1998 8
1999 7
2000 7
2001 11
2002 6
2003 13
2004 8
2005 11
2006 6
2007 12
2008 14
2009 11
2010 13
2011 17
2012 22
2013 15
2014 10
2015 25
2016 16
2017 17
2018 17
2019 11
2020 17
2021 16
2022 18
2023 15
2024 7

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366 results

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Page 1
Schizophrenia risk from complex variation of complement component 4.
Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Daly MJ, Carroll MC, Stevens B, McCarroll SA. Sekar A, et al. Nature. 2016 Feb 11;530(7589):177-83. doi: 10.1038/nature16549. Epub 2016 Jan 27. Nature. 2016. PMID: 26814963 Free PMC article.
Schizophrenia's strongest genetic association at a population level involves variation in the major histocompatibility complex (MHC) locus, but the genes and molecular mechanisms accounting for this have been challenging to identify. Here we show that this association arises …
Schizophrenia's strongest genetic association at a population level involves variation in the major histocompatibility complex (MHC) locus, …
The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis.
Ikeda N, Kubota H, Suzuki R, Morita M, Yoshimura A, Osada Y, Kishida K, Kitamura D, Iwata A, Yotsumoto S, Kurotaki D, Nishimura K, Nishiyama A, Tamura T, Kamatani T, Tsunoda T, Murakawa M, Asahina Y, Hayashi Y, Harada H, Harada Y, Yokota A, Hirai H, Seki T, Kuwahara M, Yamashita M, Shichino S, Tanaka M, Asano K. Ikeda N, et al. Cell Rep. 2023 Mar 28;42(3):112165. doi: 10.1016/j.celrep.2023.112165. Epub 2023 Feb 28. Cell Rep. 2023. PMID: 36862552 Free article.
In this study we find that Ym1(+)Ly6C(hi) monocytes, an immunoregulatory entity of neutrophil-like monocytes, arise from progenitors of neutrophil 1 (proNeu1). Granulocyte-colony stimulating factor (G-CSF) favors the production of neutrophil-like monocytes through previous …
In this study we find that Ym1(+)Ly6C(hi) monocytes, an immunoregulatory entity of neutrophil-like monocytes, arise from progenitors …
Effectiveness of Etoposide and Cisplatin vs Irinotecan and Cisplatin Therapy for Patients With Advanced Neuroendocrine Carcinoma of the Digestive System: The TOPIC-NEC Phase 3 Randomized Clinical Trial.
Morizane C, Machida N, Honma Y, Okusaka T, Boku N, Kato K, Nomura S, Hiraoka N, Sekine S, Taniguchi H, Okano N, Yamaguchi K, Sato T, Ikeda M, Mizuno N, Ozaka M, Kataoka T, Ueno M, Kitagawa Y, Terashima M, Furuse J; Japan Clinical Oncology Group (JCOG). Morizane C, et al. JAMA Oncol. 2022 Oct 1;8(10):1447-1455. doi: 10.1001/jamaoncol.2022.3395. JAMA Oncol. 2022. PMID: 35980649 Free PMC article. Clinical Trial.
DESIGN, SETTING, AND PARTICIPANTS: This open-label phase 3 randomized clinical trial enrolled chemotherapy-naive patients aged 20 to 75 years who had recurrent or unresectable NEC (according to the 2010 World Health Organization classification system) arising from the gast …
DESIGN, SETTING, AND PARTICIPANTS: This open-label phase 3 randomized clinical trial enrolled chemotherapy-naive patients aged 20 to 75 year …
Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder.
Long HK, Osterwalder M, Welsh IC, Hansen K, Davies JOJ, Liu YE, Koska M, Adams AT, Aho R, Arora N, Ikeda K, Williams RM, Sauka-Spengler T, Porteus MH, Mohun T, Dickel DE, Swigut T, Hughes JR, Higgs DR, Visel A, Selleri L, Wysocka J. Long HK, et al. Cell Stem Cell. 2020 Nov 5;27(5):765-783.e14. doi: 10.1016/j.stem.2020.09.001. Epub 2020 Sep 28. Cell Stem Cell. 2020. PMID: 32991838 Free PMC article.
Using mouse models, we demonstrate that PRS phenotypic specificity arises from the convergence of two mechanisms: confinement of Sox9 dosage perturbation to developing facial structures through context-specific enhancer activity and heightened sensitivity of the lower jaw …
Using mouse models, we demonstrate that PRS phenotypic specificity arises from the convergence of two mechanisms: confinement of Sox9 …
Lipid metabolic vulnerabilities of multiple myeloma.
Torcasio R, Gallo Cantafio ME, Ikeda RK, Ganino L, Viglietto G, Amodio N. Torcasio R, et al. Clin Exp Med. 2023 Nov;23(7):3373-3390. doi: 10.1007/s10238-023-01174-2. Epub 2023 Aug 28. Clin Exp Med. 2023. PMID: 37639069 Free PMC article. Review.
These findings will provide a new path to understanding the mechanisms underlying how lipid vulnerabilities may arise and affect the phenotype of malignant plasma cells, highlighting novel druggable pathways with a significant impact on the management of MM....
These findings will provide a new path to understanding the mechanisms underlying how lipid vulnerabilities may arise and affect the …
A medico-legal definition of femicide.
Cecchi R, Sassani M, Agugiaro G, Caroppo E, De Lellis P, Sannella A, Mazza M, Ikeda T, Kondo T, Masotti V. Cecchi R, et al. Leg Med (Tokyo). 2022 Nov;59:102101. doi: 10.1016/j.legalmed.2022.102101. Epub 2022 Jun 21. Leg Med (Tokyo). 2022. PMID: 35763984 Review.
Additionally, a non-homogeneous framing of the term femicide arises from the forensic pathology literature and national laws. Starting from one of the funding principle of medical ethics - autonomy - authors propose to define femicide as a murder perpetrated because of a f …
Additionally, a non-homogeneous framing of the term femicide arises from the forensic pathology literature and national laws. Startin …
Surgery for Thyroid Cancer Invading the Trachea.
Tsutsui H, Tamura A, Ito J, Ohara R, Hoshi M, Kubota M, Yano Y, Ikeda N. Tsutsui H, et al. Indian J Surg Oncol. 2022 Mar;13(1):184-190. doi: 10.1007/s13193-021-01466-7. Epub 2021 Oct 27. Indian J Surg Oncol. 2022. PMID: 35462665 Free PMC article. Review.
The treatment plan for thyroid cancer is determined based on the site, depth, and extent of the invasion. Different from tumours arising from the tracheal mucosa, in thyroid cancer, invasion begins outside the airway and progresses toward the lumen, making it difficult to …
The treatment plan for thyroid cancer is determined based on the site, depth, and extent of the invasion. Different from tumours arising …
Cellular carcinogenesis in preleukemic conditions:drivers and defenses.
Ueda K, Ikeda K. Ueda K, et al. Fukushima J Med Sci. 2024 Jan 27;70(1):11-24. doi: 10.5387/fms.2023-17. Epub 2023 Nov 11. Fukushima J Med Sci. 2024. PMID: 37952978 Free PMC article. Review.
Acute myeloid leukemia (AML) arises from preleukemic conditions. We have investigated the pathogenesis of typical preleukemia, myeloproliferative neoplasms, and clonal hematopoiesis. ...
Acute myeloid leukemia (AML) arises from preleukemic conditions. We have investigated the pathogenesis of typical preleukemia, myelop …
Novel therapeutic strategies targeting UCP2 in uterine leiomyosarcoma.
Nagao Y, Yokoi A, Yoshida K, Sugiyama M, Watanabe E, Nakamura K, Kitagawa M, Asano-Inami E, Koya Y, Yoshihara M, Tamauchi S, Shimizu Y, Ikeda Y, Yoshikawa N, Kato T, Yamamoto Y, Kajiyama H. Nagao Y, et al. Pharmacol Res. 2023 Mar;189:106693. doi: 10.1016/j.phrs.2023.106693. Epub 2023 Feb 10. Pharmacol Res. 2023. PMID: 36773710 Free article.
Uterine leiomyosarcoma (ULMS) is a malignant stromal tumor arising from the myometrium with a poor prognosis and very limited response to current chemotherapy. ...
Uterine leiomyosarcoma (ULMS) is a malignant stromal tumor arising from the myometrium with a poor prognosis and very limited respons …
Paratesticular myxoma.
Yoshimura K, Inoue H, Koide T, Ohnishi S. Yoshimura K, et al. Urol Int. 1994;52(4):231-2. doi: 10.1159/000282617. Urol Int. 1994. PMID: 8030175 Free article.
We report a case of paratesticular myxoma. These tumors, which arise from mesenchymal tissues, occur in a variety of sites, the most common being subcutaneous tissues and skeletal muscles but they rarely have been reported to originate in the paratesticular region. ...
We report a case of paratesticular myxoma. These tumors, which arise from mesenchymal tissues, occur in a variety of sites, the most …
366 results