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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1813 1
1830 2
1836 2
1839 1
1842 1
1847 1
1848 1
1861 1
1864 1
1867 1
1874 2
1875 1
1879 2
1880 2
1882 1
1883 4
1887 2
1888 1
1890 1
1891 1
1892 1
1894 1
1895 1
1897 4
1898 1
1899 2
1900 1
1901 2
1902 5
1903 2
1904 2
1905 7
1906 3
1907 2
1908 7
1909 7
1910 4
1911 7
1912 8
1913 16
1914 10
1915 10
1916 11
1917 9
1918 13
1919 5
1920 22
1921 20
1922 20
1923 19
1924 12
1925 17
1926 15
1927 20
1928 18
1929 13
1930 21
1931 17
1932 25
1933 18
1934 20
1935 16
1936 16
1937 18
1938 17
1939 23
1940 17
1941 18
1942 9
1943 11
1944 13
1945 32
1946 96
1947 99
1948 103
1949 109
1950 111
1951 140
1952 175
1953 197
1954 181
1955 215
1956 233
1957 220
1958 245
1959 257
1960 289
1961 248
1962 327
1963 405
1964 416
1965 440
1966 484
1967 545
1968 571
1969 721
1970 755
1971 792
1972 833
1973 855
1974 919
1975 3149
1976 3421
1977 3193
1978 3432
1979 3727
1980 4109
1981 4464
1982 4943
1983 6061
1984 6721
1985 7064
1986 7505
1987 8065
1988 8647
1989 10686
1990 10985
1991 11904
1992 12789
1993 13827
1994 14132
1995 15235
1996 16012
1997 16941
1998 17701
1999 18745
2000 20257
2001 21208
2002 22402
2003 24104
2004 26689
2005 29751
2006 32540
2007 35247
2008 37707
2009 40040
2010 44190
2011 47997
2012 52147
2013 55952
2014 58322
2015 60724
2016 61336
2017 63427
2018 66345
2019 69827
2020 81529
2021 88578
2022 88215
2023 88559
2024 41427

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1,363,410 results

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Page 1
Toll-like receptor and RIG-I-like receptor signaling.
Kawai T, Akira S. Kawai T, et al. Ann N Y Acad Sci. 2008 Nov;1143:1-20. doi: 10.1196/annals.1443.020. Ann N Y Acad Sci. 2008. PMID: 19076341 Review.
Toll-like receptors (TLRs) and RIG-I-like receptors (RLRs) constitute distinct families of pattern-recognition receptors that sense nucleic acids derived from viruses and trigger antiviral innate immune responses. ...
Toll-like receptors (TLRs) and RIG-I-like receptors (RLRs) constitute distinct families of pattern-recognition receptors that …
Lead- and drug-like compounds: the rule-of-five revolution.
Lipinski CA. Lipinski CA. Drug Discov Today Technol. 2004 Dec;1(4):337-41. doi: 10.1016/j.ddtec.2004.11.007. Drug Discov Today Technol. 2004. PMID: 24981612
Trends in the RO5 literature explosion that can be discerned are the further definitions of drug-like. This topic is explored in terms of drug-like physicochemical features, drug-like structural features, a comparison of drug-like and non-drug-like …
Trends in the RO5 literature explosion that can be discerned are the further definitions of drug-like. This topic is explored in term …
Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide.
Lau J, Bloch P, Schäffer L, Pettersson I, Spetzler J, Kofoed J, Madsen K, Knudsen LB, McGuire J, Steensgaard DB, Strauss HM, Gram DX, Knudsen SM, Nielsen FS, Thygesen P, Reedtz-Runge S, Kruse T. Lau J, et al. J Med Chem. 2015 Sep 24;58(18):7370-80. doi: 10.1021/acs.jmedchem.5b00726. Epub 2015 Sep 11. J Med Chem. 2015. PMID: 26308095
Liraglutide is an acylated glucagon-like peptide-1 (GLP-1) analogue that binds to serum albumin in vivo and is approved for once-daily treatment of diabetes as well as obesity. ...
Liraglutide is an acylated glucagon-like peptide-1 (GLP-1) analogue that binds to serum albumin in vivo and is approved for once-dail …
Toll-like receptor signaling.
Lim KH, Staudt LM. Lim KH, et al. Cold Spring Harb Perspect Biol. 2013 Jan 1;5(1):a011247. doi: 10.1101/cshperspect.a011247. Cold Spring Harb Perspect Biol. 2013. PMID: 23284045 Free PMC article. Review.
Toll-like receptors sense pathogen-associated molecular patterns (e.g., lipopolysaccharides) and trigger gene-expression changes that ultimately eradicate the invading microbes....
Toll-like receptors sense pathogen-associated molecular patterns (e.g., lipopolysaccharides) and trigger gene-expression changes that …
Regulation of angiopoietin-like protein 8 expression under different nutritional and metabolic status.
Guo C, Zhao Z, Deng X, Chen Z, Tu Z, Yuan G. Guo C, et al. Endocr J. 2019 Dec 25;66(12):1039-1046. doi: 10.1507/endocrj.EJ19-0263. Epub 2019 Oct 19. Endocr J. 2019. PMID: 31631098 Free article. Review.
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease with increasing prevalence worldwide. Angiopoietin-like protein 8 (ANGPTL8), a member of the angiopoietin-like protein family, is involved in glucose metabolism, lipid metabolism, and energy homeostasis …
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease with increasing prevalence worldwide. Angiopoietin-like protein 8 (ANG …
An Update on Toll-like Receptor 2, Its Function and Dimerization in Pro- and Anti-Inflammatory Processes.
Colleselli K, Stierschneider A, Wiesner C. Colleselli K, et al. Int J Mol Sci. 2023 Aug 5;24(15):12464. doi: 10.3390/ijms241512464. Int J Mol Sci. 2023. PMID: 37569837 Free PMC article. Review.
While a certain level of inflammation is critical for humans to survive infection and injury, a prolonged inflammatory response can have fatal consequences. Pattern recognition Toll-like receptors (TLRs) are key players in the initiation of an inflammatory process. ...
While a certain level of inflammation is critical for humans to survive infection and injury, a prolonged inflammatory response can have fat …
Toll-like receptors and the eye.
Micera A, Stampachiacchiere B, Aronni S, dos Santos MS, Lambiase A. Micera A, et al. Curr Opin Allergy Clin Immunol. 2005 Oct;5(5):451-8. doi: 10.1097/01.all.0000182537.55650.99. Curr Opin Allergy Clin Immunol. 2005. PMID: 16131923 Review.
The expression/distribution of Toll-like receptors in the healthy eye highlights the possible function of Toll-like receptors in both innate and adaptive responses during pathological conditions of the ocular surface. ...Understanding the complex mechanisms underlyi …
The expression/distribution of Toll-like receptors in the healthy eye highlights the possible function of Toll-like receptors …
Toll-like receptors and viral immunity.
Woodland D. Woodland D. Viral Immunol. 2012 Oct;25(5):347. doi: 10.1089/vim.2012.ed.25.5. Viral Immunol. 2012. PMID: 23035850 No abstract available.
Current state and confusion of twig-like middle cerebral artery.
Yu J. Yu J. Interv Neuroradiol. 2022 Aug 17:15910199221121380. doi: 10.1177/15910199221121380. Online ahead of print. Interv Neuroradiol. 2022. PMID: 35979607
In addition, we proposed a reasonable grading system for twig-like MCAs, which is significant. For a twig-like MCA, the pathogenesis is unclear, and congenital and acquired factors can be involved. A twig-like MCA disturbed cerebral hemodynamics. An associate …
In addition, we proposed a reasonable grading system for twig-like MCAs, which is significant. For a twig-like MCA, the pathog …
Roles of Kruppel-Like Transcription Factors KLF6 and KLF15 in Proximal Tubular Metabolism.
Piret SE. Piret SE. Nephron. 2023;147(12):766-768. doi: 10.1159/000531336. Epub 2023 Jun 1. Nephron. 2023. PMID: 37263229 Free article. Review.
Members of the Kruppel-like family of transcription factors are widely expressed, including in the kidney. ...
Members of the Kruppel-like family of transcription factors are widely expressed, including in the kidney. ...
1,363,410 results
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