Decreased PCSK9 expression in human hepatocellular carcinoma.
Bhat M, Skill N, Marcus V, Deschenes M, Tan X, Bouteaud J, Negi S, Awan Z, Aikin R, Kwan J, Amre R, Tabaries S, Hassanain M, Seidah NG, Maluccio M, Siegel P, Metrakos P.
Bhat M, et al.
BMC Gastroenterol. 2015 Dec 16;15:176. doi: 10.1186/s12876-015-0371-6.
BMC Gastroenterol. 2015.
PMID: 26674961
Free PMC article.
In response, there has been much interest in tumor metabolism as a therapeutic target. PCSK9 stimulates internalization of the LDL-receptor, decreases cholesterol uptake into hepatocytes and affects liver regeneration. ...Larger-scale studies should be conducted to determi …
In response, there has been much interest in tumor metabolism as a therapeutic target. PCSK9 stimulates internalization of the LDL-re …