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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1965 1
1966 1
1967 1
1969 3
1972 1
1974 1
1975 1
1976 3
1977 1
1978 3
1979 2
1980 6
1981 8
1982 6
1983 12
1984 17
1985 12
1986 16
1987 15
1988 16
1989 22
1990 21
1991 22
1992 23
1993 24
1994 19
1995 24
1996 18
1997 17
1998 24
1999 22
2000 16
2001 25
2002 28
2003 27
2004 18
2005 16
2006 20
2007 22
2008 21
2009 27
2010 24
2011 32
2012 34
2013 41
2014 44
2015 39
2016 44
2017 33
2018 52
2019 48
2020 58
2021 62
2022 57
2023 60
2024 20

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1,135 results

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Page 1
Comparative genomics of the ADA clade within the Nostocales.
Dreher TW, Davis EW 2nd, Mueller RS, Otten TG. Dreher TW, et al. Harmful Algae. 2021 Apr;104:102037. doi: 10.1016/j.hal.2021.102037. Epub 2021 May 10. Harmful Algae. 2021. PMID: 34023075
Fourteen genomes are complete (closed), enabling highly detailed assessments of gene content and genome architecture. ADA genomes contain 5 rRNA operons, genes expected to support a photoautotrophic and diazotrophic lifestyle, and a varied array of genes for the syn …
Fourteen genomes are complete (closed), enabling highly detailed assessments of gene content and genome architecture. ADA genomes …
Characterization of a metazoan ADA acetyltransferase complex.
Soffers JHM, Li X, Saraf A, Seidel CW, Florens L, Washburn MP, Abmayr SM, Workman JL. Soffers JHM, et al. Nucleic Acids Res. 2019 Apr 23;47(7):3383-3394. doi: 10.1093/nar/gkz042. Nucleic Acids Res. 2019. PMID: 30715476 Free PMC article.
In flies and mammals, Gcn5 (and its homolog pCAF) is part of various versions of the SAGA complex and another large acetyltransferase complex, ATAC (Ada2A containing acetyltransferase complex). However, a complex analogous to the small ADA complex in yeast has never …
In flies and mammals, Gcn5 (and its homolog pCAF) is part of various versions of the SAGA complex and another large acetyltransferase comple …
A new andrographolide derivative ADA targeting SIRT3-FOXO3a signaling mitigates cognitive impairment by activating mitophagy and inhibiting neuroinflammation in Apoe4 mice.
Zhou Y, Zhao Q, Zhang Y, Di L, Xue F, Xu W, Gao W, Guo Y, He Y, Kou J, Qin Y, Xie X, Du L, Han G, Pang X. Zhou Y, et al. Phytomedicine. 2024 Feb;124:155298. doi: 10.1016/j.phymed.2023.155298. Epub 2023 Dec 17. Phytomedicine. 2024. PMID: 38185066
Inhibited SIRT3 and FOXO3a in Apoe4 mice brains were elevated after ADA treatment. ADA also lightened the neuroinflammation caused by NLRP3 inflammasome activation. ...CONCLUSION: ADA exerted stronger cognition-enhancing ability in relative to AGA, and ADA …
Inhibited SIRT3 and FOXO3a in Apoe4 mice brains were elevated after ADA treatment. ADA also lightened the neuroinflammation ca …
Adenosine-Metabolizing Enzymes, Adenosine Kinase and Adenosine Deaminase, in Cancer.
Zhulai G, Oleinik E, Shibaev M, Ignatev K. Zhulai G, et al. Biomolecules. 2022 Mar 8;12(3):418. doi: 10.3390/biom12030418. Biomolecules. 2022. PMID: 35327609 Free PMC article. Review.
However, numerous enzymatic pathways that control ATP-adenosine balance, as well as understudied intracellular adenosine regulation, can prevent successful immunotherapy. This review contains the latest data on two adenosine-lowering enzymes: adenosine kinase (ADK) and ade …
However, numerous enzymatic pathways that control ATP-adenosine balance, as well as understudied intracellular adenosine regulation, can pre …
The Gcn5 complexes in Drosophila as a model for metazoa.
Torres-Zelada EF, Weake VM. Torres-Zelada EF, et al. Biochim Biophys Acta Gene Regul Mech. 2021 Feb;1864(2):194610. doi: 10.1016/j.bbagrm.2020.194610. Epub 2020 Jul 28. Biochim Biophys Acta Gene Regul Mech. 2021. PMID: 32735945 Review.
We outline the composition and activity of the four different Gcn5 complexes in Drosophila: the Spt-Ada-Gcn5 Acetyltransferase (SAGA), Ada2a-containing (ATAC), Ada2/Gcn5/Ada3 transcription activator (ADA), and Chiffon Histone Acetyltransferase (CHAT) complexe …
We outline the composition and activity of the four different Gcn5 complexes in Drosophila: the Spt-Ada-Gcn5 Acetyltransferase (SAGA) …
ANKLE DISTRACTION ARTHROPLASTY: A SYSTEMATIC REVIEW.
Lutsenko A, Ananin D, Prizov A, Lazko F. Lutsenko A, et al. Georgian Med News. 2022 Oct;(331):12-21. Georgian Med News. 2022. PMID: 36539124
One of the methods of delaying radical intervention is ankle joint distraction arthroplasty of the ankle joint (ADA), including a combination of various techniques. The lack of publications summarizing the maximum possible clinical data on ADA for more than 50 years …
One of the methods of delaying radical intervention is ankle joint distraction arthroplasty of the ankle joint (ADA), including a com …
Hazardous waste management.
Schaefer ME. Schaefer ME. Dent Clin North Am. 1991 Apr;35(2):383-90. Dent Clin North Am. 1991. PMID: 2032582 Review.
Once it has been established what constitutes hazardous waste, the next steps are to contain it, store it, and finally dispose of it according to the information gained from the authorities. ...Solid waste should usually be contained in red bags, which are then bagg …
Once it has been established what constitutes hazardous waste, the next steps are to contain it, store it, and finally dispose of it …
Mental Illness Disclosure in the Workplace: An Opportunity for Improvement.
Branning G, Waters HC, Houle CR, Worthy SL, Fink B, Hayes K. Branning G, et al. Am Health Drug Benefits. 2021 Dec;14(4):147-153. Am Health Drug Benefits. 2021. PMID: 35261719 Free PMC article. Review.
However, the ADA also states that an employer is not required to hire or keep an individual with a psychiatric disability if it poses a direct threat to his or her safety or the safety of others. ...Private companies showed more variability than public in whether applicati …
However, the ADA also states that an employer is not required to hire or keep an individual with a psychiatric disability if it poses …
What do the structures of GCN5-containing complexes teach us about their function?
Helmlinger D, Papai G, Devys D, Tora L. Helmlinger D, et al. Biochim Biophys Acta Gene Regul Mech. 2021 Feb;1864(2):194614. doi: 10.1016/j.bbagrm.2020.194614. Epub 2020 Jul 31. Biochim Biophys Acta Gene Regul Mech. 2021. PMID: 32739556 Free article. Review.
Gcn5 was subsequently identified as a subunit of the HAT module of the Spt-Ada-Gcn5-acetyltransferase (SAGA) complex, which is an experimental paradigm for multifunctional co-activators. ...In this review, we summarize recent advances in the structure of Gcn5-containing …
Gcn5 was subsequently identified as a subunit of the HAT module of the Spt-Ada-Gcn5-acetyltransferase (SAGA) complex, which is an exp …
PEGylated Recombinant Adenosine Deaminase Maintains Detoxification and Lymphocyte Counts in Patients with ADA-SCID.
Dorsey MJ, Rubinstein A, Lehman H, Fausnight T, Wiley JM, Haddad E. Dorsey MJ, et al. J Clin Immunol. 2023 Jul;43(5):951-964. doi: 10.1007/s10875-022-01426-y. Epub 2023 Feb 25. J Clin Immunol. 2023. PMID: 36840835 Free PMC article.
PURPOSE: Metabolic detoxification with enzyme replacement therapy (ERT) promotes immune recovery in patients with adenosine deaminase (ADA)-deficient severe combined immunodeficiency (ADA-SCID). Elapegademase is a PEGylated recombinant bovine ADA ERT develope …
PURPOSE: Metabolic detoxification with enzyme replacement therapy (ERT) promotes immune recovery in patients with adenosine deaminase (AD …
1,135 results