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D-2-hydroxyglutarate supports a tolerogenic phenotype with lowered major histocompatibility class II expression in non-malignant dendritic cells and acute myeloid leukemia cells.
Hammon K, Renner K, Althammer M, Voll F, Babl N, Decking SM, Siska PJ, Matos C, Conejo ZEC, Mendes K, Einwag F, Siegmund H, Iberl S, Berger RS, Dettmer K, Schoenmehl R, Brochhausen C, Herr W, Oefner PJ, Rehli M, Thomas S, Kreutz M. Hammon K, et al. Among authors: conejo zec. Haematologica. 2024 Jan 18. doi: 10.3324/haematol.2023.283597. Online ahead of print. Haematologica. 2024. PMID: 38235501 Free article.
D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization.
Böttcher M, Renner K, Berger R, Mentz K, Thomas S, Cardenas-Conejo ZE, Dettmer K, Oefner PJ, Mackensen A, Kreutz M, Mougiakakos D. Böttcher M, et al. Among authors: cardenas conejo ze. Oncoimmunology. 2018 Mar 26;7(7):e1445454. doi: 10.1080/2162402X.2018.1445454. eCollection 2018. Oncoimmunology. 2018. PMID: 29900057 Free PMC article.
First report of begomoviruses infecting Cucumis sativus L. in North America and identification of a proposed new begomovirus species.
Sanchez-Chavez S, Regla-Marquez CF, Cardenas-Conejo ZE, Garcia-Rodriguez DA, Centeno-Leija S, Serrano-Posada H, Liñan-Rico A, Partida-Palacios BL, Cardenas-Conejo Y. Sanchez-Chavez S, et al. Among authors: cardenas conejo ze. PeerJ. 2020 Jul 10;8:e9245. doi: 10.7717/peerj.9245. eCollection 2020. PeerJ. 2020. PMID: 32728488 Free PMC article.