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2020 1
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Elucidating Novel Targets for Ovarian Cancer Antibody-Drug Conjugate Development: Integrating In Silico Prediction and Surface Plasmon Resonance to Identify Targets with Enhanced Antibody Internalization Capacity.
Onyido EK, James D, Garcia-Parra J, Sinfield J, Moberg A, Coombes Z, Worthington J, Williams N, Francis LW, Conlan RS, Gonzalez D. Onyido EK, et al. Among authors: coombes z. Antibodies (Basel). 2023 Oct 16;12(4):65. doi: 10.3390/antib12040065. Antibodies (Basel). 2023. PMID: 37873862 Free PMC article.
Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells.
Quintela M, James DW, Pociute A, Powell L, Edwards K, Coombes Z, Garcia J, Garton N, Das N, Lutchman-Singh K, Margarit L, Beynon AL, Rioja I, Prinjha RK, Harker NR, Gonzalez D, Conlan RS, Francis LW. Quintela M, et al. Among authors: coombes z. Clin Epigenetics. 2023 Apr 15;15(1):63. doi: 10.1186/s13148-023-01477-x. Clin Epigenetics. 2023. PMID: 37060086 Free PMC article.