Ethanol extract of Zhongtian hawthorn lowers serum cholesterol in mice by inhibiting transcription of 3-hydroxy-3-methylglutaryl-CoA reductase via nuclear factor-kappa B signal pathway.
Hu HJ, Luo XG, Dong QQ, Mu A, Shi GL, Wang QT, Chen XY, Zhou H, Zhang TC, Pan LW.
Hu HJ, et al.
Exp Biol Med (Maywood). 2016 Mar;241(6):667-74. doi: 10.1177/1535370215627032. Epub 2016 Jan 28.
Exp Biol Med (Maywood). 2016.
PMID: 26825354
Free PMC article.
In addition, the results of luciferase reporter assay and Western blot showed that the transcriptional activity of HMGCR promoter was inhibited by Zhongtian hawthorn ethanol extract in a dose-dependent manner, while overexpression of p65 could reverse this transcriptional …
In addition, the results of luciferase reporter assay and Western blot showed that the transcriptional activity of HMGCR promoter was inhibi …