Zhengsheng Zhan - Search Results

Year	Number of Results
2012	1
2014	1
2016	2
2018	1
2020	1
2021	2
2022	2
2023	3
2024	1

1

Synthesis of triazolotriazine derivatives as c-Met inhibitors.

Guo Y, Peng X, Ji Y, Zhang Y, Ding J, Zhan Z, Ai J, Duan W. Guo Y, et al. Among authors: zhan z. Mol Divers. 2021 May;25(2):839-846. doi: 10.1007/s11030-020-10067-5. Epub 2020 Mar 10. Mol Divers. 2021. PMID: 32157572

2

Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma.

Liu Y, Zhan Z, Kang Z, Li M, Lv Y, Li S, Tong L, Feng F, Li Y, Zhang M, Xue Y, Chen Y, Zhang T, Song P, Su Y, Shen Y, Sun Y, Yang X, Chen Y, Yao S, Yang H, Wang C, Geng M, Li W, Duan W, Xie H, Ding J. Liu Y, et al. Among authors: zhan z. Acta Pharm Sin B. 2023 Dec;13(12):4748-4764. doi: 10.1016/j.apsb.2023.09.009. Epub 2023 Sep 22. Acta Pharm Sin B. 2023. PMID: 38045044 Free PMC article.

3

Design, synthesis, and STING-agonistic activity of benzo[b]thiophene-2-carboxamide derivatives.

Zhou R, Wang X, Zhang D, Zhan Z, Duan W. Zhou R, et al. Among authors: zhan z. Mol Divers. 2023 Oct 5. doi: 10.1007/s11030-023-10736-1. Online ahead of print. Mol Divers. 2023. PMID: 37796389

4

Discovery of 10H-Benzo[b]pyrido[2,3-e][1,4]oxazine AXL Inhibitors via Structure-Based Drug Design Targeting c-Met Kinase.

Zhan Z, Ji Y, Su H, Fang C, Peng X, Liu Q, Dai Y, Lin D, Xu Y, Ai J, Duan W. Zhan Z, et al. J Med Chem. 2023 Jan 12;66(1):220-234. doi: 10.1021/acs.jmedchem.2c00962. Epub 2022 Dec 16. J Med Chem. 2023. PMID: 36524812

5

Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation.

Xu D, Sun D, Wang W, Peng X, Zhan Z, Ji Y, Shen Y, Geng M, Ai J, Duan W. Xu D, et al. Among authors: zhan z. Eur J Med Chem. 2021 Aug 5;220:113497. doi: 10.1016/j.ejmech.2021.113497. Epub 2021 Apr 25. Eur J Med Chem. 2021. PMID: 33957388

6

Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation.

Xie Z, Wang Z, Fan F, Zhou J, Hu Z, Wang Q, Wang X, Zeng Q, Zhang Y, Qiu J, Zhou X, Xu H, Bai H, Zhan Z, Ding J, Zhang H, Duan W, Yu X, Geng M. Xie Z, et al. Among authors: zhan z. Cell Discov. 2022 Dec 13;8(1):133. doi: 10.1038/s41421-022-00481-4. Cell Discov. 2022. PMID: 36513640 Free PMC article.

7

Evaluation of Deuterium-Labeled JNJ38877605: Pharmacokinetic, Metabolic, and in Vivo Antitumor Profiles.

Zhan Z, Peng X, Sun Y, Ai J, Duan W. Zhan Z, et al. Chem Res Toxicol. 2018 Nov 19;31(11):1213-1218. doi: 10.1021/acs.chemrestox.8b00191. Epub 2018 Oct 16. Chem Res Toxicol. 2018. PMID: 30284817

8

Discovery of 6-(difluoro(6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl)methyl)quinoline as a highly potent and selective c-Met inhibitor.

Zhan Z, Peng X, Liu Q, Chen F, Ji Y, Yao S, Xi Y, Lin Y, Chen T, Xu Y, Ai J, Geng M, Duan W. Zhan Z, et al. Eur J Med Chem. 2016 Jun 30;116:239-251. doi: 10.1016/j.ejmech.2016.03.076. Epub 2016 Mar 31. Eur J Med Chem. 2016. PMID: 27061987

9

A Novel IRAK4 Inhibitor DW18134 Ameliorates Peritonitis and Inflammatory Bowel Disease.

Huang Y, Ning Y, Chen Z, Song P, Tang H, Shi W, Wan Z, Huang G, Liu Q, Chen Y, Zhou Y, Li Y, Zhan Z, Ding J, Duan W, Xie H. Huang Y, et al. Among authors: zhan z. Molecules. 2024 Apr 16;29(8):1803. doi: 10.3390/molecules29081803. Molecules. 2024. PMID: 38675622 Free PMC article.

10

O-linked triazolotriazines: potent and selective c-Met inhibitors.

Chen F, Wang Y, Ai J, Zhan Z, Lv Y, Liang Z, Luo C, Mei D, Geng M, Duan W. Chen F, et al. Among authors: zhan z. ChemMedChem. 2012 Jul;7(7):1276-85. doi: 10.1002/cmdc.201200145. Epub 2012 Apr 26. ChemMedChem. 2012. PMID: 22539497

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