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chen qing xi
(139 results)?
Microsomal prostaglandin E(2) synthase-1 and its inhibitors: Molecular mechanisms and therapeutic significance.
Pharmacol Res. 2022 Jan;175:105977. doi: 10.1016/j.phrs.2021.105977. Epub 2021 Nov 17.
Pharmacol Res. 2022.
PMID: 34798265
Review.
In clinical practice, non-steroidal anti-inflammatory drugs (NSAIDs) as upstream COX-2 enzyme activity inhibitors are widely used to block COX-2 cascade to relieve inflammatory response. ...Some mPGES-1 inhibitor candidates including synthetic compounds, natural products a …
In clinical practice, non-steroidal anti-inflammatory drugs (NSAIDs) as upstream COX-2 enzyme activity inhibitors are widely used to …
Rheumatoid arthritis drug sinomenine induces apoptosis of cervical tumor cells by targeting thioredoxin reductase in vitro and in vivo.
Duan D, Wang Y, Pan D, Jin X, Yan Y, Song P, Wang L, Xiao J, Wang Z, Wang X.
Duan D, et al.
Bioorg Chem. 2022 May;122:105711. doi: 10.1016/j.bioorg.2022.105711. Epub 2022 Feb 28.
Bioorg Chem. 2022.
PMID: 35247807
Sinomenine is a naturally occurring alkaloid isolated from Sinomenium acutum. The drug, Zhengqing Fengtongning made from sinomenine, has been universally applied in rheumatoid arthritis treatment in China as well as other Asian countries for decades. ...
Sinomenine is a naturally occurring alkaloid isolated from Sinomenium acutum. The drug, Zhengqing Fengtongning made from sinomenine, …
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[Effects of zhengqing fengtongning tablet and methotrexate on the serum OPG/RANKL and IL-17 of collagen-induced arthritis rats].
Ding CZ, Yao Y, Fang Y, Sun LY, Wang Y.
Ding CZ, et al.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 Feb;33(2):256-60.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013.
PMID: 23646485
Chinese.
The destruction of joints in the four limbs were observed using X-ray. The AI was recorded. The expression levels of serum OPG, RANKL, and IL-17 were detected at the end of the experiment. ...Compared with the model group, the AI decreased in the CM treatment group, …
The destruction of joints in the four limbs were observed using X-ray. The AI was recorded. The expression levels of serum OPG, RANKL …
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Sinomenine-induced histamine release-like anaphylactoid reactions are blocked by tranilast via inhibiting NF-κB signaling.
Huang L, Dong Y, Wu J, Wang P, Zhou H, Li T, Liu L.
Huang L, et al.
Pharmacol Res. 2017 Nov;125(Pt B):150-160. doi: 10.1016/j.phrs.2017.08.014. Epub 2017 Sep 1.
Pharmacol Res. 2017.
PMID: 28867637
Zhengqing Fengtongning (ZQFTN), the pharmaceutical preparation of sinomenine (SIN) derived from the medicinal plant Sinmenium acutum, is well-known in China as an effective treatment for rheumatoid arthritis (RA). ...
Zhengqing Fengtongning (ZQFTN), the pharmaceutical preparation of sinomenine (SIN) derived from the medicinal plant Sinmenium acutum, …
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