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Novel tricyclic-alpha-alkyloxyphenylpropionic acids: dual PPARalpha/gamma agonists with hypolipidemic and antidiabetic activity.
Sauerberg P, Pettersson I, Jeppesen L, Bury PS, Mogensen JP, Wassermann K, Brand CL, Sturis J, Wöldike HF, Fleckner J, Andersen AS, Mortensen SB, Svensson LA, Rasmussen HB, Lehmann SV, Polivka Z, Sindelar K, Panajotova V, Ynddal L, Wulff EM. Sauerberg P, et al. Among authors: polivka z. J Med Chem. 2002 Feb 14;45(4):789-804. doi: 10.1021/jm010964g. J Med Chem. 2002. PMID: 11831892
Identification and synthesis of a novel selective partial PPARdelta agonist with full efficacy on lipid metabolism in vitro and in vivo.
Sauerberg P, Olsen GS, Jeppesen L, Mogensen JP, Pettersson I, Jeppesen CB, Daugaard JR, Galsgaard ED, Ynddal L, Fleckner J, Panajotova V, Polivka Z, Pihera P, Havranek M, Wulff EM. Sauerberg P, et al. Among authors: polivka z. J Med Chem. 2007 Apr 5;50(7):1495-503. doi: 10.1021/jm061202u. Epub 2007 Mar 8. J Med Chem. 2007. PMID: 17343371
Design of potent PPARalpha agonists.
Sauerberg P, Mogensen JP, Jeppesen L, Bury PS, Fleckner J, Olsen GS, Jeppesen CB, Wulff EM, Pihera P, Havranek M, Polivka Z, Pettersson I. Sauerberg P, et al. Among authors: polivka z. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3198-202. doi: 10.1016/j.bmcl.2007.03.015. Epub 2007 Mar 12. Bioorg Med Chem Lett. 2007. PMID: 17379517