The Current Status of Heterogeneous Palladium Catalysed Heck and Suzuki Cross-Coupling Reactions

Philani P Mpungose; Zanele P Vundla; Glenn E M Maguire; Holger B Friedrich

doi:10.3390/molecules23071676

The Current Status of Heterogeneous Palladium Catalysed Heck and Suzuki Cross-Coupling Reactions

Molecules. 2018 Jul 10;23(7):1676. doi: 10.3390/molecules23071676.

Authors

Philani P Mpungose¹, Zanele P Vundla², Glenn E M Maguire³, Holger B Friedrich⁴

Affiliations

¹ Catalysis Research Group, School of Chemistry and Physics, University of KwaZulu-Natal, Westville Campus, Durban 4000, South Africa. 207506038@stu.ukzn.ac.za.
² Catalysis Research Group, School of Chemistry and Physics, University of KwaZulu-Natal, Westville Campus, Durban 4000, South Africa. sjaejj@gmail.com.
³ School of Chemistry and Physics, University of KwaZulu-Natal, Varsity Drive, Durban 4001, South Africa. maguireg@ukzn.ac.za.
⁴ Catalysis Research Group, School of Chemistry and Physics, University of KwaZulu-Natal, Westville Campus, Durban 4000, South Africa. friedric@ukzn.ac.za.

Abstract

In the last 30 years, C⁻C cross coupling reactions have become a reliable technique in organic synthesis due their versatility and efficiency. While drawbacks have been experienced on an industrial scale with the use of homogenous systems, many attempts have been made to facilitate a heterogeneous renaissance. Thus, this review gives an overview of the current status of the use of heterogeneous catalysts particularly in Suzuki and Heck reactions. Most recent developments focus on palladium immobilised or supported on various classes of supports, thus this review highlights and discuss contributions of the last decade.

Keywords: C–C cross coupling; Heck cross-coupling; Suzuki cross-coupling; heterogeneous palladium catalysis.

Publication types

Review

MeSH terms

Catalysis
Chemistry Techniques, Synthetic / methods*
Magnetics
Nanoparticles / chemistry
Oxides / chemistry
Palladium / chemistry*

Substances

Oxides
Palladium