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Page 1
Showing results for aiming tan
Search for Zaiming Tan instead (1 results)
Single-cell RNA-seq analysis reveals BHLHE40-driven pro-tumour neutrophils with hyperactivated glycolysis in pancreatic tumour microenvironment.
Wang L, Liu Y, Dai Y, Tang X, Yin T, Wang C, Wang T, Dong L, Shi M, Qin J, Xue M, Cao Y, Liu J, Liu P, Huang J, Wen C, Zhang J, Xu Z, Bai F, Deng X, Peng C, Chen H, Jiang L, Chen S, Shen B. Wang L, et al. Gut. 2023 May;72(5):958-971. doi: 10.1136/gutjnl-2021-326070. Epub 2022 Jun 10. Gut. 2023. PMID: 35688610 Free PMC article.
RESULTS: Exploration of the heterogeneity of tumour-associated neutrophils (TANs) revealed a terminally differentiated pro-tumour subpopulation (TAN-1) associated with poor prognosis, an inflammatory subpopulation (TAN-2), a population of transitional stage that hav …
RESULTS: Exploration of the heterogeneity of tumour-associated neutrophils (TANs) revealed a terminally differentiated pro-tumour subpopulat …
Tanshinone I inhibits doxorubicin-induced cardiotoxicity by regulating Nrf2 signaling pathway.
Jiang Q, Chen X, Tian X, Zhang J, Xue S, Jiang Y, Liu T, Wang X, Sun Q, Hong Y, Li C, Guo D, Wang Y, Wang Q. Jiang Q, et al. Phytomedicine. 2022 Nov;106:154439. doi: 10.1016/j.phymed.2022.154439. Epub 2022 Sep 6. Phytomedicine. 2022. PMID: 36108374
PURPOSE: This study aimed to explore whether Tan I can protect against DIC and to reveal whether Tan I can exert anti-oxidative effect by regulating nuclear erythroid factor 2-related factor 2 (Nrf2) pathway. ...The oxidative stress induced by DOX was suppres …
PURPOSE: This study aimed to explore whether Tan I can protect against DIC and to reveal whether Tan I can exert anti-o …
Tanshinone I attenuates the malignant biological properties of ovarian cancer by inducing apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway.
Zhou J, Jiang YY, Chen H, Wu YC, Zhang L. Zhou J, et al. Cell Prolif. 2020 Feb;53(2):e12739. doi: 10.1111/cpr.12739. Epub 2019 Dec 9. Cell Prolif. 2020. PMID: 31820522 Free PMC article.
It has been shown that Tan-I exhibited anti-tumour activities on different types of cancers. ...Thus, this study aimed to access the therapy effect of Tan- and the underlying mechanisms. ...
It has been shown that Tan-I exhibited anti-tumour activities on different types of cancers. ...Thus, this study aimed to acce …
The Singapore National Precision Medicine Strategy.
Wong E, Bertin N, Hebrard M, Tirado-Magallanes R, Bellis C, Lim WK, Chua CY, Tong PML, Chua R, Mak K, Lim TM, Cheong WY, Thien KE, Goh KT, Chai JF, Lee J, Sung JJ, Wong TY, Chin CWL, Gluckman PD, Goh LL, Ban KHK, Tan TW; SG10K_Health Consortium; Sim X, Cheng CY, Davila S, Karnani N, Leong KP, Liu J, Prabhakar S, Maurer-Stroh S, Verma CS, Krishnaswamy P, Goh RSM, Chia I, Ho C, Low D, Virabhak S, Yong J, Zheng W, Seow SW, Seck YK, Koh M, Chambers JC, Tai ES, Tan P. Wong E, et al. Nat Genet. 2023 Feb;55(2):178-186. doi: 10.1038/s41588-022-01274-x. Epub 2023 Jan 19. Nat Genet. 2023. PMID: 36658435 Review.
The Singapore National Precision Medicine initiative is a whole-of-government 10-year initiative aiming to generate precision medicine data of up to one million individuals, integrating genomic, lifestyle, health, social and environmental data. ...
The Singapore National Precision Medicine initiative is a whole-of-government 10-year initiative aiming to generate precision medicin …
Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies.
Cupp MA, Cariolou M, Tzoulaki I, Aune D, Evangelou E, Berlanga-Taylor AJ. Cupp MA, et al. BMC Med. 2020 Nov 20;18(1):360. doi: 10.1186/s12916-020-01817-1. BMC Med. 2020. PMID: 33213430 Free PMC article.
BACKGROUND: Although neutrophils have been linked to the progression of cancer, uncertainty exists around their association with cancer outcomes, depending on the site, outcome and treatments considered. We aimed to evaluate the strength and validity of evidence on the ass …
BACKGROUND: Although neutrophils have been linked to the progression of cancer, uncertainty exists around their association with cancer outc …
Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE/NF-κB signaling pathway in vivo and in vitro.
Ding B, Lin C, Liu Q, He Y, Ruganzu JB, Jin H, Peng X, Ji S, Ma Y, Yang W. Ding B, et al. J Neuroinflammation. 2020 Oct 14;17(1):302. doi: 10.1186/s12974-020-01981-4. J Neuroinflammation. 2020. PMID: 33054814 Free PMC article.
The receptor for advanced glycation end products (RAGE)-mediated signaling pathway is related to amyloid beta (Abeta)-induced neuroinflammation. This study aimed to investigate the neuroprotective effects of tanshinone IIA (tan IIA), a natural product isolated from …
The receptor for advanced glycation end products (RAGE)-mediated signaling pathway is related to amyloid beta (Abeta)-induced neuroinflammat …
Protective effect of total Saponins from American ginseng against cigarette smoke-induced COPD in mice based on integrated metabolomics and network pharmacology.
Lin H, Wang C, Yu H, Liu Y, Tan L, He S, Li Z, Wang C, Wang F, Li P, Liu J. Lin H, et al. Biomed Pharmacother. 2022 May;149:112823. doi: 10.1016/j.biopha.2022.112823. Epub 2022 Mar 23. Biomed Pharmacother. 2022. PMID: 35334426 Free article.
Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory disease. Aiming at assessing the effect of total saponins from American ginseng on COPD, both the chemical composition and anti-COPD activity of total saponins from wild-simulated American ginseng (TSW …
Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory disease. Aiming at assessing the effect of total saponins fro …
Neodymium-Sensitized Nanoconstructs for Near-Infrared Enabled Photomedicine.
Yu Z, Chan WK, Tan TTY. Yu Z, et al. Small. 2020 Jan;16(1):e1905265. doi: 10.1002/smll.201905265. Epub 2019 Nov 29. Small. 2020. PMID: 31782909 Review.
This review article will contribute to the design and fabrication of novel Nd(3+) -sensitized nanoconstructs for NIR-enabled photomedicine, aiming for potentially safer and more efficient designs to get closer to clinical usage....
This review article will contribute to the design and fabrication of novel Nd(3+) -sensitized nanoconstructs for NIR-enabled photomedicine, …
Aptamer-Protein Interactions: From Regulation to Biomolecular Detection.
Ji C, Wei J, Zhang L, Hou X, Tan J, Yuan Q, Tan W. Ji C, et al. Chem Rev. 2023 Nov 22;123(22):12471-12506. doi: 10.1021/acs.chemrev.3c00377. Epub 2023 Nov 6. Chem Rev. 2023. PMID: 37931070 Review.
Finally, we present our perspectives regarding the opportunities and challenges of analytical assays for biological analysis, aiming to provide guidance for disease mechanism research and drug discovery....
Finally, we present our perspectives regarding the opportunities and challenges of analytical assays for biological analysis, aiming …
9,816 results