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Reprogramming cell fate with a genome-scale library of artificial transcription factors.
Eguchi A, Wleklinski MJ, Spurgat MC, Heiderscheit EA, Kropornicka AS, Vu CK, Bhimsaria D, Swanson SA, Stewart R, Ramanathan P, Kamp TJ, Slukvin I, Thomson JA, Dutton JR, Ansari AZ. Eguchi A, et al. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):E8257-E8266. doi: 10.1073/pnas.1611142114. Epub 2016 Dec 5. Proc Natl Acad Sci U S A. 2016. PMID: 27930301 Free PMC article.
Synthetic genome readers target clustered binding sites across diverse chromatin states.
Erwin GS, Grieshop MP, Bhimsaria D, Do TJ, Rodríguez-Martínez JA, Mehta C, Khanna K, Swanson SA, Stewart R, Thomson JA, Ramanathan P, Ansari AZ. Erwin GS, et al. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7418-E7427. doi: 10.1073/pnas.1604847113. Epub 2016 Nov 8. Proc Natl Acad Sci U S A. 2016. PMID: 27830652 Free PMC article.
Specificity landscapes of DNA binding molecules elucidate biological function.
Carlson CD, Warren CL, Hauschild KE, Ozers MS, Qadir N, Bhimsaria D, Lee Y, Cerrina F, Ansari AZ. Carlson CD, et al. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4544-9. doi: 10.1073/pnas.0914023107. Epub 2010 Feb 22. Proc Natl Acad Sci U S A. 2010. PMID: 20176964 Free PMC article.
Possible involvement of oxidative stress in cisplatin-induced apoptosis in LLC-PK1 cells.
Xiao T, Choudhary S, Zhang W, Ansari NH, Salahudeen A. Xiao T, et al. J Toxicol Environ Health A. 2003 Mar 14;66(5):469-79. doi: 10.1080/15287390306449. J Toxicol Environ Health A. 2003. PMID: 12712633
Expression of oncogenes c-myc and p53 was induced, and except for caspase 1, all the other caspases tested were activated. Z-VAD, the broad-spectrum inhibitor of caspases, prevented caspase activation and apoptosis, but not c-myc and p53 induction. ...
Expression of oncogenes c-myc and p53 was induced, and except for caspase 1, all the other caspases tested were activated. Z-VAD, the …
Role of Solvent Polarity and Hydrogen-Bonding on Excited-State Fluorescence of 3-[(E)-{4-[Dimethylamino]benzylidene}amino]-2-naphthoic Acid (DMAMN): Isomerization vs Rotomerization.
Al-Ansari IAZ. Al-Ansari IAZ. J Phys Chem A. 2018 Feb 22;122(7):1838-1854. doi: 10.1021/acs.jpca.7b11623. Epub 2018 Feb 12. J Phys Chem A. 2018. PMID: 29381869
On the basis of the generated potential energy landscapes of the ground state and low-lying excited state in the gas phase and solution, we found that selective photon absorption, brings this molecule to a "bright" state, from which NC isomerization Z E, takes place. This …
On the basis of the generated potential energy landscapes of the ground state and low-lying excited state in the gas phase and solution, we …