Recent Advances in the Enantioselective Radical Reactions

Molecules. 2023 Aug 25;28(17):6252. doi: 10.3390/molecules28176252.

Abstract

The review covers research published since 2017 and is focused on enantioselective synthesis using radical reactions. It describes recent approaches to the asymmetric synthesis of chiral molecules based on the application of the metal catalysis, dual metal and organocatalysis and finally, pure organocatalysis including enzyme catalysis. This review focuses on the synthetic aspects of the methodology and tries to show which compounds can be obtained in enantiomerically enriched forms.

Keywords: enantioselective synthesis; enzymes; organocatalysis; radical chemistry; transition metal catalysis.

Publication types

  • Review

Grants and funding

This research received no external funding.