Evaluating the Intoxicating Degree of Liquor Products with Combinations of Fusel Alcohols, Acids, and Esters

Molecules. 2018 May 23;23(6):1239. doi: 10.3390/molecules23061239.

Abstract

To investigate the effects of fusel alcohols on the intoxicating degree of liquor products, formulated liquors (FLs) were prepared by blending 1-propanol, isobutanol, and isoamyl alcohol with ethanol, organic acids, and corresponding ethyl esters to simulate the formula of traditional Chinese liquors. The prepared FLs were submitted for evaluation of their intoxicating degree (ID). The results showed that the fusel alcohols had a biphasic effect on the IDs of the FLs, depending on the comprehensive coordination of the characteristic minor components. The importance of the suitable ratio of alcohols/acids/esters (RAAE) on the IDs was also revealed. Under an optimal ratio level, the fusel alcohols exhibited negligible effects on the IDs of the FLs. Moreover, the ratio of isoamyl alcohol to isobutanol (IA/IB) showed a strong positive correlation to the IDs of the FLs. This study lays a foundation for the potential application in producing low-ID liquor.

Keywords: alcohol consumption; fusel alcohols; intoxicating degree; liquor products; mice model.

MeSH terms

  • Alcoholic Beverages / analysis
  • Alcoholic Beverages / toxicity*
  • Alcohols / chemistry*
  • Amino Acids / chemistry*
  • Animals
  • Behavior, Animal / drug effects*
  • Esters / chemistry*
  • Male
  • Mice
  • Random Allocation

Substances

  • Alcohols
  • Amino Acids
  • Esters