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Synthesis of 2-chloropurine ribosides with chiral amino acid amides at C6 and their evaluation as A1 adenosine receptor agonists.
Berzina MY, Eletskaya BZ, Kayushin AL, Dorofeeva EV, Lutonina OI, Fateev IV, Paramonov AS, Kostromina MA, Zayats EA, Abramchik YA, Maltsev DV, Naumenko LV, Taran AS, Yakovlev DS, Spasov AA, Miroshnikov AI, Esipov RS, Konstantinova ID. Berzina MY, et al. Among authors: abramchik ya. Bioorg Chem. 2022 Sep;126:105878. doi: 10.1016/j.bioorg.2022.105878. Epub 2022 May 18. Bioorg Chem. 2022. PMID: 35660725
Rational Mutagenesis in the Lid Domain of Ribokinase from E. coli Results in an Order of Magnitude Increase in Activity towards D-arabinose.
Zayats EA, Fateev IV, Kostromina MA, Abramchik YA, Lykoshin DD, Yurovskaya DO, Timofeev VI, Berzina MY, Eletskaya BZ, Konstantinova ID, Esipov RS. Zayats EA, et al. Among authors: abramchik ya. Int J Mol Sci. 2022 Oct 19;23(20):12540. doi: 10.3390/ijms232012540. Int J Mol Sci. 2022. PMID: 36293391 Free PMC article.