Use of Head and Chest Circumference Ratio as an Index of Fetal Growth Retardation in Preterm Infants

Nutrients. 2022 Nov 21;14(22):4942. doi: 10.3390/nu14224942.

Abstract

We evaluated the relationship between fetal growth in preterm babies using the head circumference (HC)/chest circumference (CC) ratio and other anthropometric parameters at birth and at school age. Data were collected from 187 very low birth weight (VLBW) children born at less than 30 weeks of gestational age (GA) at birth and at 6 years. We assessed the correlation between the HC/CC ratio and body weight (BW), body length (BL), and HC z-scores at birth, and BW, body height (BH), and body mass index (BMI) z-scores at 6 years. Multiple regression analysis showed that BW z-score, BL z-score, and HC z-score at birth were significantly associated with HC/CC at birth. The BMI z-score at 6 years was also significantly associated with HC/CC at birth. The HC/CC ratio at birth is a reliable parameter for evaluating fetal growth restriction and a possible predictor of physical growth in VLBW children.

Keywords: body mass index; fetal growth restriction; head circumference to chest circumference ratio; very low birth weight infants.

MeSH terms

  • Body Height
  • Child
  • Female
  • Fetal Growth Retardation* / diagnosis
  • Gestational Age
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Premature*
  • Infant, Very Low Birth Weight

Grants and funding

This research received no external funding.