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PTEN at a glance.
Shi Y, Paluch BE, Wang X, Jiang X. Shi Y, et al. J Cell Sci. 2012 Oct 15;125(Pt 20):4687-92. doi: 10.1242/jcs.093765. J Cell Sci. 2012. PMID: 23223894 Free PMC article. Review. No abstract available.
Targeting hepatic glutaminase activity to ameliorate hyperglycemia.
Miller RA, Shi Y, Lu W, Pirman DA, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett JK, Park JO, Zhang Y, Holland WL, Rabinowitz JD, Birnbaum MJ. Miller RA, et al. Among authors: shi y. Nat Med. 2018 May;24(4):518-524. doi: 10.1038/nm.4514. Epub 2018 Mar 26. Nat Med. 2018. PMID: 29578539 Free PMC article.
PTEN is a protein tyrosine phosphatase for IRS1.
Shi Y, Wang J, Chandarlapaty S, Cross J, Thompson C, Rosen N, Jiang X. Shi Y, et al. Nat Struct Mol Biol. 2014 Jun;21(6):522-7. doi: 10.1038/nsmb.2828. Epub 2014 May 11. Nat Struct Mol Biol. 2014. PMID: 24814346 Free PMC article.
Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models.
Esquejo RM, Salatto CT, Delmore J, Albuquerque B, Reyes A, Shi Y, Moccia R, Cokorinos E, Peloquin M, Monetti M, Barricklow J, Bollinger E, Smith BK, Day EA, Nguyen C, Geoghegan KF, Kreeger JM, Opsahl A, Ward J, Kalgutkar AS, Tess D, Butler L, Shirai N, Osborne TF, Steinberg GR, Birnbaum MJ, Cameron KO, Miller RA. Esquejo RM, et al. Among authors: shi y. EBioMedicine. 2018 May;31:122-132. doi: 10.1016/j.ebiom.2018.04.009. Epub 2018 Apr 8. EBioMedicine. 2018. PMID: 29673898 Free PMC article.