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2004 1
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Page 1
Ensartinib vs Crizotinib for Patients With Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer: A Randomized Clinical Trial.
Horn L, Wang Z, Wu G, Poddubskaya E, Mok T, Reck M, Wakelee H, Chiappori AA, Lee DH, Breder V, Orlov S, Cicin I, Cheng Y, Liu Y, Fan Y, Whisenant JG, Zhou Y, Oertel V, Harrow K, Liang C, Mao L, Selvaggi G, Wu YL. Horn L, et al. JAMA Oncol. 2021 Nov 1;7(11):1617-1625. doi: 10.1001/jamaoncol.2021.3523. JAMA Oncol. 2021. PMID: 34473194 Free PMC article. Clinical Trial.
Efficacy was evaluated in the intent-to-treat (ITT) population as well as a prespecified modified ITT (mITT) population consisting of patients with central laboratory-confirmed ALK-positive NSCLC. RESULTS: A total of 290 patients (149 men [51.4%]; median age, 54 years [ran …
Efficacy was evaluated in the intent-to-treat (ITT) population as well as a prespecified modified ITT (mITT) population consisting of patien …
Preventive percutaneous coronary intervention versus optimal medical therapy alone for the treatment of vulnerable atherosclerotic coronary plaques (PREVENT): a multicentre, open-label, randomised controlled trial.
Park SJ, Ahn JM, Kang DY, Yun SC, Ahn YK, Kim WJ, Nam CW, Jeong JO, Chae IH, Shiomi H, Kao HL, Hahn JY, Her SH, Lee BK, Ahn TH, Chang KY, Chae JK, Smyth D, Mintz GS, Stone GW, Park DW; PREVENT Investigators. Park SJ, et al. Lancet. 2024 Apr 4:S0140-6736(24)00413-6. doi: 10.1016/S0140-6736(24)00413-6. Online ahead of print. Lancet. 2024. PMID: 38604213
FINDINGS: Between Sept 23, 2015, and Sept 29, 2021, 5627 patients were screened for eligibility, 1606 of whom were enrolled and randomly assigned to percutaneous coronary intervention (n=803) or optimal medical therapy alone (n=803). 1177 (73%) patients were men and 429 (2 …
FINDINGS: Between Sept 23, 2015, and Sept 29, 2021, 5627 patients were screened for eligibility, 1606 of whom were enrolled and randomly ass …
Real-world clinical practice and outcomes in treating stage III non-small cell lung cancer: KINDLE-Asia subset.
Prabhash K, Tan DSW, Soo RA, Sitthideatphaiboon P, Chen YM, Voon PJ, Syahruddin E, Chu S, Huggenberger R, Cho BC. Prabhash K, et al. Front Oncol. 2023 Mar 27;13:1117348. doi: 10.3389/fonc.2023.1117348. eCollection 2023. Front Oncol. 2023. PMID: 37051534 Free PMC article.
RESULTS: Of the total 1874 patients (median age: 63.0 years [24 to 92]) enrolled in the Asia subset, 74.8% were men, 54.7% had stage IIIA disease, 55.7% had adenocarcinoma, 34.3% had epidermal growth factor receptor mutations (EGFRm) and 50.3% had programmed death-ligand 1 …
RESULTS: Of the total 1874 patients (median age: 63.0 years [24 to 92]) enrolled in the Asia subset, 74.8% were men, 54.7% had stage …
Improvement in Delivery of Ischemic Stroke Treatments but Stagnation of Clinical Outcomes in Young Adults in South Korea.
Kim J, Kim JY, Kang J, Kim BJ, Han MK, Lee JY, Park TH, Lee KJ, Kim JT, Choi KH, Park JM, Kang K, Lee SJ, Kim JG, Cha JK, Kim DH, Lee K, Lee J, Hong KS, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Kim DE, Ryu WS, Choi JC, Kwon JH, Kim WJ, Shin DI, Yum KS, Sohn SI, Hong JH, Lee SH, Lee JS, Lee J, Gorelick PB, Bae HJ. Kim J, et al. Stroke. 2023 Dec;54(12):3002-3011. doi: 10.1161/STROKEAHA.123.044619. Epub 2023 Nov 9. Stroke. 2023. PMID: 37942640
Secular trends for patient characteristics, treatments, and outcomes were analyzed. RESULTS: A total of 7050 eligible patients (mean age, 43.1; men, 71.9%) were registered. The mean age decreased from 43.6 to 42.9 years (P(trend)=0.01). ...
Secular trends for patient characteristics, treatments, and outcomes were analyzed. RESULTS: A total of 7050 eligible patients (mean age, 43 …
Restoration of fertility in vasectomized men using percutaneous vasal or epididymal sperm aspiration.
Qiu Y, Yang DT, Wang SM. Qiu Y, et al. Contraception. 2004 Jun;69(6):497-500. doi: 10.1016/j.contraception.2004.01.008. Contraception. 2004. PMID: 15157796
OBJECTIVE: To restore fertility of vasectomized men using percutaneous epididymal sperm aspiration (PESA) and percutaneous vasal sperm aspiration (PVSA) via intrauterine insemination (IUI). PATIENTS: Twenty-eight vasectomized men who required restoration of their fe …
OBJECTIVE: To restore fertility of vasectomized men using percutaneous epididymal sperm aspiration (PESA) and percutaneous vasal sper …
Scrotal heat stress causes sperm chromatin damage and cysteinyl aspartate-spicific proteinases 3 changes in fertile men.
Zhang MH, Shi ZD, Yu JC, Zhang YP, Wang LG, Qiu Y. Zhang MH, et al. J Assist Reprod Genet. 2015 May;32(5):747-55. doi: 10.1007/s10815-015-0451-0. Epub 2015 Feb 22. J Assist Reprod Genet. 2015. PMID: 25702164 Free PMC article.
PURPOSE: To observe changes in semen parameters, sperm DNA integrity, chromatin condensation and cysteinyl aspartate-spicific proteinases (Caspase-3) in adult healthy men after scrotal heat stress (SHS). METHODS: The scrotums of 19 healthy male volunteers were exposed to t …
PURPOSE: To observe changes in semen parameters, sperm DNA integrity, chromatin condensation and cysteinyl aspartate-spicific proteinases (C …
Quality of sperm obtained by penile vibratory stimulation and percutaneous vasal sperm aspiration in men with spinal cord injury.
Qiu Y, Wang LG, Zhang LH, Zhang AD, Wang ZY. Qiu Y, et al. J Androl. 2012 Sep-Oct;33(5):1036-46. doi: 10.2164/jandrol.111.014902. Epub 2012 Mar 22. J Androl. 2012. PMID: 22441760
The aim of this study was to explore sperm chromosomal aneuploidy and DNA integrity in infertile patients with spinal cord injury (SCI). Semen samples were collected from 12 infertile men with SCI by percutaneous vasal sperm aspiration (PVSA) and from 14 male SCI patients …
The aim of this study was to explore sperm chromosomal aneuploidy and DNA integrity in infertile patients with spinal cord injury (SCI). Sem …
Comparing Non-Communicable Disease Risk Factors in Asian Migrants and Native Koreans among the Asian Population.
Piao H, Yun JM, Shin A, Cho B, Kang D. Piao H, et al. Biomol Ther (Seoul). 2022 Nov 1;30(6):603-615. doi: 10.4062/biomolther.2022.036. Epub 2022 Aug 31. Biomol Ther (Seoul). 2022. PMID: 36041857 Free PMC article.
Among the participants aged 20, the age-adjusted prevalence of current smoking was higher among Chinese and other Asian migrant men than among Korean men and women (p<0.001 and p<0.001, respectively). ...
Among the participants aged 20, the age-adjusted prevalence of current smoking was higher among Chinese and other Asian migrant men t …
Machine Learning Prediction for the Recurrence After Electrical Cardioversion of Patients With Persistent Atrial Fibrillation.
Kwon S, Lee E, Ju H, Ahn HJ, Lee SR, Choi EK, Suh J, Oh S, Rhee W. Kwon S, et al. Korean Circ J. 2023 Oct;53(10):677-689. doi: 10.4070/kcj.2023.0012. Epub 2023 Jul 24. Korean Circ J. 2023. PMID: 37653713 Free PMC article.
The performance was compared to the C-statistics of the selected clinical features. RESULTS: Among 718 patients (mean age 63.59.3 years, men 78.8%), AF recurred in 435 (60.6%) patients after 1 month. With the XGBoost-based model, the areas under the receiver operating char …
The performance was compared to the C-statistics of the selected clinical features. RESULTS: Among 718 patients (mean age 63.59.3 years, …
21 results