Loss of Dact2 alleviates cisplatin-induced nephrotoxicity through regulation of the Igfl-MAPK pathway axis.
Kim C, Kwak W, Won DH, Kim J, Hwang DB, Kim N, Kang M, Jeon Y, Park YI, Park JW, Yun JW.
Kim C, et al. Among authors: jeon y.
Cell Biol Toxicol. 2023 Dec;39(6):3197-3217. doi: 10.1007/s10565-023-09827-4. Epub 2023 Aug 21.
Cell Biol Toxicol. 2023.
PMID: 37603122
The injury was alleviated in Dact2 KO mice, which showed lower levels of blood urea nitrogen and creatinine. ...In RNA-seq analysis comparing WT and Dact2 KO mice after cisplatin treatment, genes related to "Apoptosis" and "Activation of mitogen-activated protein ki …
The injury was alleviated in Dact2 KO mice, which showed lower levels of blood urea nitrogen and creatinine. ...In RNA-seq analysis c …